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The potential of clusterin inhibiting antisense oligodeoxynucleotide therapy for prostate cancer

この作品が含まれる作品: Expert Opinion on Investigational Drugs

出版日: 2006-05-01

言語: 英語

main subject: 前立腺癌

Cites articles 74

Date

タイトル

著者

2005-07-01

Androgen deprivation therapy for prostate cancer.

James L. Gulley, William Dahut
2005-01-27

Mechanisms of the development of androgen independence in prostate cancer

Colleen Nelson
2005-11-01

A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells
2005-08-21

Clusterin inhibits apoptosis by interacting with activated Bax

Russell S. Taichman
2005-01-26

Use of antisense oligonucleotides targeting the cytoprotective gene, clusterin, to enhance androgen- and chemo-sensitivity in prostate cancer
2005-09-01

Antisense oligodeoxynucleotide therapy targeting clusterin gene for prostate cancer: Vancouver experience from discovery to clinic
2005-02-01

Therapeutic efficacy of adenoviral-mediated p53 gene transfer is synergistically enhanced by combined use of antisense oligodeoxynucleotide targeting clusterin gene in a human bladder cancer model
2005-06-01

Antisense therapy for cancer.
2005-04-30

Efficacy of an intratumoral controlled release formulation of clusterin antisense oligonucleotide complexed with chitosan containing paclitaxel or docetaxel in prostate cancer xenograft models

Helen M. Burt
2005-11-25

The inhibition of angiogenesis by antisense oligonucleotides to clusterin

Helen M. Burt
2005-09-01

A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer
2005-01-01

Antisense oligonucleotides: the state of the art.
2005-01-01

Peptide nucleic acids (PNAs), a chemical overview

Andrea Porcheddu
2005-10-01

Expression of the secreted form of clusterin protein in renal cell carcinoma as a predictor of disease extension
2004-10-07

Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer

Ian F. Tannock
2004-10-07

Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
2004-03-01

Osteoblast-derived factors induce androgen-independent proliferation and expression of prostate-specific antigen in human prostate cancer cells

Bassam Masri, Marianne Sadar, Nicholas Bruchovsky
2004-12-01

Protection of androgen-dependent human prostate cancer cells from oxidative stress-induced DNA damage by overexpression of clusterin and its modulation by androgen
2004-01-01

Clusterin as a possible predictor for biochemical recurrence of prostate cancer following radical prostatectomy with intermediate Gleason scores: a preliminary report
2004-10-01

Clusterin-mediated apoptosis is regulated by adenomatous polyposis coli and is p21 dependent but p53 independent

Saverio Bettuzzi
2004-11-01

Clusterin overexpression in both malignant and nonmalignant prostate epithelial cells induces cell cycle arrest and apoptosis

Norman Maitland
2004-09-01

Intracellular clusterin induces G2-M phase arrest and cell death in PC-3 prostate cancer cells1

Saverio Bettuzzi
2004-03-01

Modulation of different clusterin isoforms in human colon tumorigenesis

Luigi Giusto Spagnoli
2004-03-01

Silencing expression of the clusterin/apolipoprotein j gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress

Efstathios S. Gonos
2004-06-01

Synergistic antitumor activity by combined treatment with gemcitabine and antisense oligodeoxynucleotide targeting clusterin gene in an intravesical administration model against human bladder cancer kotcc-1 cells
2004-09-01

Heat shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer
2004-02-01

Glycobiology and cancer: meeting summary and future diections
2003-03-01

Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases

Isaiah J. Fidler
2003-09-01

Overexpression of the cytoprotective protein clusterin decreases radiosensitivity in the human LNCaP prostate tumour model
2003-07-01

Repression of IR-inducible clusterin expression by the p53 tumor suppressor protein,Repression of IR-Inducible Clusterin Expression by the p53 Tumor Suppressor Protein

Dmitry Klokov
2003-07-25

Essential requirement of apolipoprotein J (clusterin) signaling for IkappaB expression and regulation of NF-kappaB activity.

Bruce J Aronow
2003-01-24

Synthesis and functional analyses of nuclear clusterin, a cell death protein

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