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Effects of a novel Nodal-targeting monoclonal antibody in melanoma

author

Antonio Leonardi

published in: Oncotarget

date of publication: 2015-10-09

language: English

Cites articles 52

Date

Title

Authors

2015-09-07

New Anti-Nodal Monoclonal Antibodies Targeting the Nodal Pre-Helix Loop Involved in Cripto-1 Binding

Rosanna Palumbo, Antonio Leonardi
2015-03-12

Targeting nodal in conjunction with dacarbazine induces synergistic anticancer effects in metastatic melanoma

Richard Scolyer
2015-02-13

Phenotype switching in melanoma: implications for progression and therapy

Grant McArthur, Robin L Anderson
2015-02-12

Increased expression of Nodal correlates with reduced patient survival in pancreatic cancer

Helmut Friess, Irene Esposito
2015-01-01

Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway
2015-01-01

Improved overall survival in melanoma with combined dabrafenib and trametinib

Dirk Schadendorf, Paul Lorigan, Antoni Ribas, Axel Hauschild, Reinhard Dummer, Caroline Robert, Kamil Drucis, Piotr Rutkowski, Georgina V. Long, Keith Flaherty, Andrzej Mackiewicz, Jacob Schachter
2015-03-18

Overall survival in patients with metastatic melanoma
2015-01-15

Conformational features and binding affinities to Cripto, ALK7 and ALK4 of Nodal synthetic fragments

Luisa Calvanese, Andrea Caporale
2015-03-01

Essential dynamics analysis captures the concerted motion of the integrin-binding site in jerdostatin, an RTS disintegrin

Luisa Calvanese
2014-11-01

The melanoma revolution: from UV carcinogenesis to a new era in therapeutics

Jennifer A Lo, David E. Fisher
2014-09-25

Internalization by multiple endocytic pathways and lysosomal processing impact maspin-based therapeutics
2014-08-11

Tumor heterogeneity and plasticity as elusive drivers for resistance to MAPK pathway inhibition in melanoma
2014-12

Nodal signaling promotes a tumorigenic phenotype in human breast cancer
2014-10

Stem cells and targeted approaches to melanoma cure
2014-12-31

Immunotherapies and novel combinations: the focus of advances in the treatment of melanoma

Paolo Antonio Ascierto
2014-09-29

Divergence(s) in nodal signaling between aggressive melanoma and embryonic stem cells

Andrew P Hinck
2014-12-02

Increased MAPK reactivation in early resistance to dabrafenib/trametinib combination therapy of BRAF-mutant metastatic melanoma

Richard Scolyer, Georgina V. Long, Alexander M Menzies, Peter Johansson, Richard F. Kefford, Helen Rizos, John F Thompson, Varsha Tembe, Gulietta M Pupo, Robyn Saw, Matteo Carlino, Carina Fung, Jessica Hyman, Julie R Howle, Hamideh Shahheydari
2014-05-01

Melanoma, version 4.2014.

National Comprehensive Cancer Network, F Stephen Hodi
2013-08-05

Phase II trial (BREAK-2) of the BRAF inhibitor dabrafenib (GSK2118436) in patients with metastatic melanoma

Jean-Jacques Grob, Dirk Schadendorf, Paolo Antonio Ascierto, Georgina V. Long, Antoni Ribas, Ester Simeone
2013-07-12

Neuroblastoma cells injected into experimental mature teratoma reveal a tropism for embryonic loose mesenchyme
2013-03-19

Advances in personalized targeted treatment of metastatic melanoma and non-invasive tumor monitoring

Mel Ziman, Elin S Gray
2013-01-21

Nodal promotes invasive phenotypes via a mitogen-activated protein kinase-dependent pathway
2013-02-24

Experience in daily practice with ipilimumab for the treatment of patients with metastatic melanoma: an early increase in lymphocyte and eosinophil counts is associated with improved survival

Emilie Lanoy, Caroline Robert
2012-11-21

MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling

Chong Sun, Ultan McDermott, Sjaak Neefjes, René Bernards
2012-07-20

A landscape of driver mutations in melanoma

Eric Lander, Gad Getz, Kristian Cibulskis, Wendy Winckler, Daniel Auclair, Gordon Saksena, Eran Hodis, Nicolas Stransky, Douglas Voet, Kristin Ardlie, Elizabeth Nickerson, Lynda Chin, Jean-Philippe Theurillat, Marcin Imielinski, Dirk Schadendorf, Jennifer Wargo, Donald Morton, John E. Ladbury, Gregory Kryukov, Katherine Stemke-Hale, Stefan T Arold, Stephan N. Wagner, Matthew Meyerson, Stacey Gabriel, Levi A Garraway, Andrey Sivachenko, Alex H Ramos
2012-06-04

Improved survival with MEK inhibition in BRAF-mutated melanoma

Claus Garbe, Mohammed Milhem, Piotr Rutkowski, Jochen Utikal, Jürgen C Becker, Reinhard Dummer
2012-06-28

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

Mario Sznol, Charles G. Drake, F Stephen Hodi, Tracee L. McMiller, Suzanne L. Topalian, Drew M Pardoll, Janis M Taube
2012-05-11

Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer

Edith A. Perez, Wilma L Lingle
2011-08-01

Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells

Mitchell G Lawrence, Daniela Loessner, Lynne-Marie Postovit, Judith Clements
2011-06-30

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

Dirk Schadendorf, Antoni Ribas, Paul Lorigan, Claus Garbe, Axel Hauschild, Reinhard Dummer, Michele Maio, Alexander Eggermont, Caroline Robert, Grant McArthur, Keith Flaherty, Paolo Antonio Ascierto, James Larkin, John B A G Haanen, David Hogg, Alessandro Testori, Jeffrey A Sosman, Celeste Lebbe, Thomas Jouary
2011-09-15

Nodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 transcription in ovarian cancer cells
2011-04-04

Embryonic signaling in melanoma: potential for diagnosis and therapy

Article - wd:Q36544020

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