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FLASH assembly of TALENs for high-throughput genome editing

লেখক

J. Keith Joung

এতে প্রকাশিত: Nature Biotechnology

তারিখে প্রকাশিত: 2012-05-01

Cites articles 33

তারিখ

শিরোনাম

লেখকগণ

2011-10-20

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

Elena Miranda, Stefan Marciniak, Ignacio Varela, James P Di Santo, Ludovic Vallier, Helene Strick-Marchand, David E Paschon, Pei-Qi Liu
2011-09-01

TAL effectors: customizable proteins for DNA targeting

Adam Bogdanove
2011-08-07

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

J. Keith Joung
2011-08-07

An unbiased genome-wide analysis of zinc-finger nuclease specificity

Christof von Kalle, Luigi Naldini, Pietro Genovese, Angelo Leone Lombardo, Philip D Gregory, Manfred Schmidt
2011-08-03

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity

Toni Cathomen
2011-07-07

Genetic engineering of human pluripotent cells using TALE nucleases

Dirk Hockemeyer, Gregory J Cost, Philip D Gregory, Rudolf Jaenisch, Edward Rebar, Fyodor Urnov
2011-07-15

Targeted genome editing across species using ZFNs and TALENs

অ্যান্ড্রু জে উড, Philip D Gregory, Lei Zhang, Edward Rebar, Fyodor Urnov, Xiangdong Meng
2011

Transcriptional activators of human genes with programmable DNA-specificity

Ulla Bonas
2011

Assembly of designer TAL effectors by Golden Gate cloning

Sylvestre Marillonnet
2011-07

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
2011-03-31

Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes
2011-03-18

Assembly of custom TALE-type DNA binding domains by modular cloning
2011-01-24

De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks

Magdy M. Mahfouz, Jian-Kang Zhu
2011-02

Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

Simona Lodato, Sriram Kosuri, George M. Church, Paola Arlotta
2011-01-05

TAL effectors are remote controls for gene activation
2011-02

A TALE nuclease architecture for efficient genome editing

Kyle A Barlow, Kevin L Hua, Gregory J Cost, Philip D Gregory, Lei Zhang, Edward Rebar, Fyodor Urnov, David E Paschon, Sarah J Hinkley, Irina Ankoudinova
2011-01

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

Yannick Doyon, Philip D Gregory, Fyodor Urnov
2011-08-05

Heritable gene targeting in zebrafish using customized TALENs.
2011-08-05

Targeted gene disruption in somatic zebrafish cells using engineered TALENs

J. Keith Joung
2011-08-05

Knockout rats generated by embryo microinjection of TALENs.

Philip D Gregory, Gregory J Cost, Lei Zhang
2011-06-01

Human umbilical cord blood cells restore brain damage induced changes in rat somatosensory cortex
2010-11-24

Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors
2010-08-10

TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

Bing Yang
2010-01-01

A rapid and general assay for monitoring endogenous gene modification

Dmitry Guschin, Edward Rebar
2010-10

Targeting DNA double-strand breaks with TAL effector nucleases

Adam Bogdanove
2010-06-01

TAL effectors: finding plant genes for disease and defense

Sebastian Schornack, Adam Bogdanove
2009-12-11

Breaking the code of DNA binding specificity of TAL-type III effectors

Ulla Bonas, Sebastian Schornack
2009-12-11

A simple cipher governs DNA recognition by TAL effectors

Adam Bogdanove
2009-05-21

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

Hyung Joo Lee, Seung Woo Cho
2008-07-01

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

Erica Unger-Wallace, Drena Dobbs, Paul B McCray, Toni Cathomen, Daniel F Voytas, A John Iafrate, J. Keith Joung
2007-07

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

David J. Segal, Toni Cathomen
2007-07

An improved zinc-finger nuclease architecture for highly specific genome editing

Adam J Waite, Philip D Gregory, Edward Rebar

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