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mTOR, translation initiation and cancer

published in: Oncogene

date of publication: 2006-10-01

language: English

Cites articles 76

Date

Title

Authors

2006-03-13

Decreased expression of eukaryotic initiation factor 3f deregulates translation and apoptosis in tumor cells

Jiaqi Shi
2006-03-09

The TOR signalling network from yeast to man.

Robbie Loewith
2006-03-16

mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin

Jeffrey Shabanowitz
2006-05-01

Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53
2006-01-16

Translational regulation of TRAIL sensitivity.
2006-01-01

mTOR signaling: implications for cancer and anticancer therapy.
2006-06-21

The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

Nahum Sonenberg, Virginie Mieulet, Philippe P. Roux
2006-02-01

Vascular endothelial growth factor-regulated ovarian cancer invasion and migration involves expression and activation of matrix metalloproteinases
2006-02-01

Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis
2006-02-09

Activation of p70S6K induces expression of matrix metalloproteinase 9 associated with hepatocyte growth factor-mediated invasion in human ovarian cancer cells
2005-12

Exploiting the PI3K/AKT pathway for cancer drug discovery
2005-11-18

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

Steven P. Gygi
2005-03-23

Growth inhibition of head and neck squamous carcinoma cells by small interfering RNAs targeting eIF4E or cyclin D1 alone or combined with cisplatin
2005-10-01

mTOR controls FLIPS translation and TRAIL sensitivity in glioblastoma multiforme cells
2005-12-01

eIF3: a connecTOR of S6K1 to the translation preinitiation complex

David M. Sabatini
2005-06-01

The eukaryotic initiation factor 4E-binding proteins and apoptosis

Christopher G. Proud
2005-08-01

Phosphoinositide 3-kinases as drug targets in cancer

Roger L. Williams, Leonard R. Stephens, Phillip Thomas Hawkins
2005-08-01

mTOR--beyond transplantation
2004-06-01

Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells

Nahum Sonenberg, David M. Perlman, Douglas Yee, Peter B Bitterman, Svetlana V Avdulov, David Burrichter, J Carlos Manivel, Vitaly A Polunovsky
2004-01

mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E

Andrew R. Tee
2004-08-15

Upstream and downstream of mTOR

Nahum Sonenberg
2004-01-01

Raptor and mTOR: subunits of a nutrient-sensitive complex,Raptor and mTOR: Subunits of a Nutrient-Sensitive Complex
2004-02-27

Translation initiation factor 4E blocks endoplasmic reticulum-mediated apoptosis
2004-04-01

eIF4E--from translation to transformation

Nahum Sonenberg
2004-04

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

Virginie Mieulet, George Thomas
2004-01-01

Role of mTOR signalling in the control of translation initiation and elongation by nutrients,Role of mTOR Signalling in the Control of Translation Initiation and Elongation by Nutrients
2004-11-01

Targeting the molecular target of rapamycin (mTOR).
2004-04-18

The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis

Pier Paolo Pandolfi, Carlos Cordon-Cardo, Davide Ruggero
2004-03-01

Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer

Outi Saramäki, Tapio Visakorpi
2004-04-01

The role of c-myc in regulation of translation initiation
2004-08-26

Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling

Heath D Skinner, Bing-Hua Jiang
2004-12-01

Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities

Ivan Topisirovic

Article - wd:Q36623679

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