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Developing mRNA-vaccine technologies

author

Mariola Fotin-Mleczek

1967 -

Karl-Josef Kallen

published in: RNA Biology

date of publication: 2012-10-12

language: English

main subject: RNA vaccine

Cites articles 152

Date

Title

Authors

2012-04-24

In vivo gene delivery by nonviral vectors: overcoming hurdles?

Yuan Zhang, Andrew Satterlee, Leaf Huang
2012-04-08

Systematic discovery of structural elements governing stability of mammalian messenger RNAs
2012-02-14

Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin

Katalin Karikó, Drew Weissman, Hiromi Muramatsu
2012-06-01

Highly potent mRNA based cancer vaccines represent an attractive platform for combination therapies supporting an improved therapeutic effect

Mariola Fotin-Mleczek, Karl-Josef Kallen, Regina Heidenreich
2012-01-03

Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection

Juliana M Chan, Zeyu Xiao, Omid C. Farokhzad, Juliana Chung-ngor Chan, Robert S. Langer, Jr., Jinjun Shi, Benjamin A Teply, Etgar Levy-Nissenbaum
2012-02-01

Enhancement of Helicobacter pylori outer inflammatory protein DNA vaccine efficacy by co-delivery of interleukin-2 and B subunit heat-labile toxin gene encoded plasmids.
2012-01-20

Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety--fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis

Anna M Rydzik, Joanna Kowalska, Jacek Jemielity
2011-12-04

Soluble multi-trimeric TNF superfamily ligand adjuvants enhance immune responses to a HIV-1 Gag DNA vaccine

Richard S Kornbluth
2011-11-08

Activation of RIG-I-like receptor signal transduction
2011-09-02

Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA.

Katalin Karikó, Drew Weissman, Hiromi Muramatsu
2011-08-03

Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L

Babal Kant Jha, Robert H. Silverman, Katalin Karikó, Drew Weissman, Hiromi Muramatsu
2011-07-01

Protein expression from exogenous mRNA: uptake by receptor-mediated endocytosis and trafficking via the lysosomal pathway

Wouter P R Verdurmen, Mariola Fotin-Mleczek
2011-03-22

The impact of miRNA target sites in coding sequences and in 3'UTRs

Nikolaus Rajewsky
2011-01-09

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

Benjamin W. Neuman, Winfried Barchet, Michael S. Diamond, Luisa Cervantes-Barragán, Matthias Habjan, Roland Züst, Stuart G Siddell, Kristy J Szretter, Volker Thiel, Burkhard Ludewig, Susan C. Baker
2011-12-19

Multicomponent synthetic polymers with viral-mimetic chemistry for nucleic acid delivery

Martyn Davies, Cameron Alexander, Rujikan Nasanit, Samer R Abulateefeh, Stephanie Allen, Jon A Preece
2011-08-04

FLT3 ligand enhances the cancer therapeutic potency of naked RNA vaccines.

Uğur Şahin, Özlem Türeci, Sebastian Kreiter, Sebastian Attig, Mustafa Diken, Christoph Huber, Abderraouf Selmi, Michael Koslowski, Yves Hüsemann, Jan Diekmann
2011-03-03

Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation.

Uğur Şahin, Özlem Türeci
2011-01-09

Expression of therapeutic proteins after delivery of chemically modified mRNA in mice
2011-01-01

Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity.

Mariola Fotin-Mleczek, Karl-Josef Kallen
2011-04-04

The form of NY-ESO-1 antigen has an impact on the clinical efficacy of anti-tumor vaccination
2010-12-28

Intradermal vaccinations with RNA coding for TAA generate CD8+ and CD4+ immune responses and induce clinical benefit in vaccinated patients

Hans-Georg Rammensee, Ingmar Hoerr
2010-11-02

Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity

Uğur Şahin, Sebastian Kreiter, Mustafa Diken, Christoph Huber, Özlem Türeci, Abderraouf Selmi, Michael Koslowski, Cedrik M Britten
2010-10-01

Immunologic basis of vaccine vectors
2010-10-05

Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor

Carl H. June, Bruce L. Levine
2010-09-30

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

George Q. Daley, Alexander Meissner, James J. Collins, Chad A. Cowan, Derrick Rossi, Yuin-Han Loh, Philip D Manos, Tim Ahfeldt
2010-08-12

Mammalian microRNAs predominantly act to decrease target mRNA levels

Jonathan Weissman, David P. Bartel
2010-06-08

GM-CSF increases mucosal and systemic immunogenicity of an H1N1 influenza DNA vaccine administered into the epidermis of non-human primates

Eric Yager, Deborah H Fuller
2010-05-13

Increased interstitial pressure improves nucleic acid delivery to skin enabling a comparative analysis of constitutive promoters
2010-05-10

Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation

Katalin Karikó, Drew Weissman, Hiromi Muramatsu, Bart R Anderson, Philip C Bevilacqua, Lauren Sansing
2010-02-01

RIG-I detects viral genomic RNA during negative-strand RNA virus infection

Frank T. Vreede, Caetano Reis e Sousa, Jan Rehwinkel, Wendy Barclay, Ervin Fodor
2010-01-12

Recognition of viruses by cytoplasmic sensors

Courtney Wilkins, Michael Gale
2010-01-01

CD40-expressing plasmid induces anti-CD40 antibody and enhances immune responses to DNA vaccination

Yating Cheng, Youmin Kang

Article - wd:Q36684597

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