Inventaire - your friends and communities are your best library

The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors as a Paradigm for Cross-Species Comparative Oncogenomics

published in: The American Journal of Pathology

date of publication: 2015-12-28

language: English

main subject: genomics

Cites articles 101

Date

Title

Authors

2015-05-01

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

Andreas von Deimling, Jüri Reimand, Peter van Sluis, Hans-Jörg Warnatz, Karel Zitterbart, Martin Hasselblatt, Marie-Laure Yaspo, Ruth G. Tatevossian, Stephen C Mack, Volker Hovestadt, Ekkehard Hewer, Rogier Versteeg, Matthias A. Karajannis, Nicholas K Foreman, Jan Koster, Gary D. Bader, Stefan M. Pfister, Vijay Ramaswamy, David Capper, Martin Sill, Peter Lichter, Stefan Rutkowski, Marcel Kool, Andrey Korshunov, David T. W. Jones, Andreas E Kulozik, Michael D. Taylor, Richard Gilbertson, Kristian W Pajtler, Kenneth D Aldape, Terri S Armstrong, Katja von Hoff, Marina Ryzhova, Laura Sieber, Richard Volckmann, Olaf Witt, Fabian Kratochwil, Pascal Johann, Leonille Schweizer, Khalida Wani, Nalin Gupta, Chandanamali Punchihewa, Zhiqin Huang, Daniel W Fults, Helen Toledano, Smadar Avigad, Lindsey Hoffman, David Zagzag
2015-06-01

Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells

Nicole M Brossier
2015-05-06

Glioblastoma: pathology, molecular mechanisms and markers

Andreas von Deimling, Guido Reifenberger
2014-09-21

PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors

Deyou Zheng, William Lee, Thomas Wiesner, Samuel Singer, Sewit Teckie
2014-07-19

Methylated RASSF1A in malignant peripheral nerve sheath tumors identifies neurofibromatosis type 1 patients with inferior prognosis

Matthias Kolberg, Piero Picci, Fredrik Mertens, Ragnhild A. Lothe, Stine A Danielsen
2014-09-10

International Society Of Neuropathology--Haarlem consensus guidelines for nervous system tumor classification and grading

Greg N. Fuller, Dominique Figarella-Branger, Andreas von Deimling, Cynthia Hawkins, Guido Reifenberger, Charles G Eberhart, Peter C. Burger, Andrey Korshunov
2014-05-13

Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis

David A Largaespada, Branden S Moriarity, Eric P Rahrmann, Adrienne Watson
2014-03-01

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity

Vincent W. Keng, David A Largaespada
2014-02-19

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

Stephen C Mack, Rosario M. Piro, Xin Wang, Xin Wang, Marco Gallo, Vijay Ramaswamy, David T. W. Jones, Martin Sill, Trevor J Pugh, David J. H. Shih, Marc Remke, Thomas Zichner, Claudia C Faria, Volker Hovestadt, Jan Koster, Till Milde, Sergio L Pereira, Pedro Castelo-Branco, Wiesława Grajkowska, Andreas von Deimling, Stephen W. Scherer, Uri Tabori, Paul N. Kongkham, William A Weiss, Mathieu Lupien, Gary D. Bader, Roland Eils, Stefan M. Pfister, Marcel Kool, Paul A Northcott, Kimberly Bertrand, James Rutka, K. Nethery-Brokx
2014-02-04

Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas

Mark W. Kieran, Frank Balis
2014-01-01

Prevalence and clinical implications of chromothripsis in cancer genomes

Jan Koster
2014-04-01

Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis

Kevin A. Roth, Nicole M Brossier
2014-10-12

Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors

Rajni B. Sharma, Bert Vogelstein, Kenneth W Kinzler, Ralph H. Hruban, Kaisorn L Chaichana, Chetan Bettegowda, Laura D Wood, Nickolas Papadopoulos, Mark Sausen, Gary L Gallia, Greg J Riggins, Ziya L Gokaslan
2013-12-03

Comparative multidimensional molecular analyses of pediatric diffuse intrinsic pontine glioma reveals distinct molecular subtypes

Madhuri Kambhampati, Amanda M. Saratsis, Javad Nazarian, Sridevi Yadavilli, Roger Packer, Eric Raabe, Brian R Rood, Suresh N Magge, Tobey J MacDonald
2013-05-19

Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis

Bernat Gel, Vincent W. Keng, Eduard Serra, Aaron L. Sarver, Branden S Moriarity, David A Largaespada, Eric P Rahrmann, Natalie K Wolf, Adrienne Watson
2013-02-21

CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors

Alexander J. Lazar
2013-01-13

Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis

Steven Carroll, Nicole M Brossier
2013-06-27

Relevance of MPNST cell lines as models for NF1 associated-tumors

Eric Pasmant
2012-12-18

Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST

Vincent W. Keng, Branden S Moriarity, David A Largaespada, Eric P Rahrmann, Adrienne Watson
2012-12-10

MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors

Walter J Jessen, Bruce J Aronow, Timothy P Cripe
2012-11-06

Impaired Pten expression in human malignant peripheral nerve sheath tumours

Andreas von Deimling, Andreas Kurtz, Frank L. Heppner, Nikola Holtkamp
2012-08-02

Dissecting the genomic complexity underlying medulloblastoma

Hans Lehrach, Marie-Laure Yaspo, Hans-Jörg Warnatz, Roland Eils, Benedikt Brors, Christof von Kalle, Guido Reifenberger, Andreas von Deimling, Christel Herold-Mende, Peter van Sluis, Andreas Unterberg, Camelia Monoranu, Ulrich Schüller, Martin Hasselblatt, Nada Jabado, Benjamin Raeder, Barbara Hutter, Thomas Zichner, Joachim Weischenfeldt, Till Milde, Martin McCabe, Simona Coco, Jan Korbel, Dominik Sturm, Tobias Rausch, Marc Zapatka, Volker Hovestadt, Trevor J Pugh, Martin Ebinger, Jochen Rössler, Jan Koster, Marc Remke, Vladimir Benes, Robert B. Russell, Stefan Wiemann, Stefan M. Pfister, Norbert Graf, Jörg Felsberg, Matthew Meyerson, Peter Lichter, Stefan Rutkowski, Manfred Schmidt, Marcel Kool, Paul A Northcott, Andrey Korshunov, David T. W. Jones, David J. H. Shih, Matthew J Betts, Andreas E Kulozik, Martin U Schuhmann, Michael D. Taylor, Scott L Pomeroy, André O von Bueren, Natalie Jäger, Marc Sultan, Yoon-Jae Cho, Adrian M Stütz, Marina Ryzhova, Sabrina V Pleier, Huriye Seker-Cin, Elke Pfaff, Laura Sieber, Sonja Hutter, Theophilos Tzaridis, Vyacheslav Amstislavskiy, Bärbel Lasitschka, Cynthia C Bartholomae, Chris Lawerenz, Jürgen Eils, Rolf Kabbe, Richard Volckmann, Gian Paolo Tonini, Olaf Witt, Eberhard Maass, Michael Christoph Frühwald, Steven Clifford, Wolfram Scheurlen
2012-08-02

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

Inanc Birol, Michelle Fèvre-Montange, Jüri Reimand, Karel Zitterbart, Almos Klekner, Uri Tabori, David Malkin, Marta Perek-Polnik, Nada Jabado, Claudia C Faria, Xin Wang, Samer K Elbabaa, Thomas Zichner, Vijay Ramaswamy, Jan Korbel, Massimo Zollo, William A Weiss, Marc Remke, François Doz, Erwin G. Van Meir, Martine F Roussel, Gary D. Bader, Andrew Mungall, Stefan M. Pfister, Olivier Delattre, Wiesława Grajkowska, Stephen W. Scherer, Maryam Fouladi, Shaun Jackman, Robert A. Holt, Eric Bouffet, Matthew Meyerson, Darell D. Bigner, Roger E McLendon, Charles G Eberhart, Marcel Kool, Richard Ellenbogen, Paul A Northcott, Andrey Korshunov, Rameen Beroukhim, James Rutka, Carlos Gilberto Carlotti, David T. W. Jones, Stephen C Mack, Linda Liau, Livia Garzia, Sorana Morrissy, Adrian M Dubuc, Betty Luu, Adi Rolider, Robert J Wechsler-Reya, Byung-Kyu Cho, Kyu-Chang Wang, Anne Jouvet, Ian F Pollack, G Yancey Gillespie, Concezio Di Rocco, Luca Massimi, Erna M C Michiels, Nanne K Kloosterhof, Johan M Kros, Reid F Thompson, Adam Fontebasso, Janet C Lindsey, Nalin Gupta, Timothy E Van Meter, Toshihiro Kumabe, Teiji Tominaga, Joshua B Rubin, Miklós Garami, Rajeev Vibhakar, Shenandoah Robinson, Scott L Pomeroy, Yoon-Jae Cho, Cynthia Hawkins, Steven Clifford, David J. H. Shih, Michael D. Taylor, Marco Marra, James M Olson, Adrian M Stütz, Wolfram Scheurlen, Daisuke Kawauchi, Christine Haberler, Leonard Jeffrey Medeiros, Eric Chuah, Richard Corbett, Steven E Schumacher, Jenny Qian, Giuseppe Cinalli, Readman Chiu
2012-07-22

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

James Bochicchio, Kristian Cibulskis, Daniel Auclair, Gad Getz, Heidi Greulich, James Meldrim, Carsten Russ, Aaron McKenna, Petar Stojanov, Jill P. Mesirov, David T. W. Jones, Matthew Meyerson, Trevor J Pugh, Stacey Gabriel, Peter Lichter, Andrey Sivachenko, Stefan M. Pfister, Paul A Northcott, Pablo Tamayo, Scott L Pomeroy, Yoon-Jae Cho, Vladimir Amani, Tenley C. Archer, Scott L Carter, Michael D. Taylor, Natalie Jäger
2012-09

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

Alexandre Montpetit, Jeremy Schwartzentruber, Andreas von Deimling, Dong-Anh Khuong-Quang, Nada Jabado, Adam Fleming, Dominik Sturm, Stefan M. Pfister, Guillaume Bourque, Eric Bouffet, Ute Bartels, Cynthia Hawkins, Peter Lichter, Marcel Kool, Andrey Korshunov, Jacek Majewski, David T. W. Jones
2012-02-28

Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas

Felipe Andreiuolo, Pascale Varlet, Jacques Grill, Chris Jones, Gwénaël Le Teuff, Birgit Geoerger
2012-02-23

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

Magnus L Bäcklund, Martin McCabe, Jan Koster, Marc Remke, Stefan M. Pfister, Dannis G van Vuurden, Olivier Delattre, Franck Bourdeaut, Peter Lichter, Stefan Rutkowski, Marcel Kool, Paul A Northcott, Andrey Korshunov, David T. W. Jones, François Doz, Scott L Pomeroy, Yoon-Jae Cho, Christine Haberler, Michael D. Taylor, Richard Gilbertson, Steven Clifford, Antoinette Y N Schouten-van Meeteren, André O von Bueren
2012-02-10

A prognostic gene expression signature in infratentorial ependymoma

Maryam Fouladi, Antonio Omuro, Tom Mikkelsen, Riccardo Soffietti
2012-03

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

Elaine Mardis, Robert Huether, Alberto Broniscer, Charles G. Mullighan, Matthew Parker
2012-01-29

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Jeremy Schwartzentruber, David T. W. Jones, Dominik Sturm, Volker Hovestadt, Anders M Lindroth, Tobias Rausch, Jan Korbel, Martin Ebinger, Magdalena Zakrzewska, Marc Zapatka, Andreas von Deimling, Till Milde, Pedro Castelo-Branco, Uri Tabori, Stefan M. Pfister, Peter Lichter, Marcel Kool, Andrey Korshunov, Jacek Majewski, Paweł P. Liberski, Andreas E Kulozik, Martin U Schuhmann, Natalie Jäger, Marina Ryzhova, Elke Pfaff, Olaf Witt, Michael Christoph Frühwald, Wolfram Scheurlen, Nada Jabado, Christoph Plass, Dong-Anh Khuong-Quang, Adam Fontebasso, Damien Faury, David Malkin, Guido Reifenberger, Karine Jacob, Martje Tönjes, André Nantel, Carolin Konermann, Thomas Hielscher, Miklós Garami, Arnulf Pekrun, Matthias Dürken, Alexandre Montpetit, Krzystof Zakrzewski, Zhifeng Dong, Peter M Siegel, Abhijit Guha Roy, Koichi Ichimura
2012-01-18

The pan erbB inhibitor PD168393 enhances lysosomal dysfunction-induced apoptotic death in malignant peripheral nerve sheath tumor cells

Niroop Kaza, Steven Carroll, Kevin A. Roth
2011-12-11

Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms

Steven Carroll

Article - wd:Q36753692

Welcome to Inventaire

the library of your friends and communities

learn more