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The translational landscape of mTOR signalling steers cancer initiation and metastasis

author

Jonathan Weissman

1950 -

published in: Nature

date of publication: 2012-02-22

language: English

Cites articles 40

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2011-02

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
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Translation initiation factors and active sites of protein synthesis co-localize at the leading edge of migrating fibroblasts
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eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

Pier Paolo Pandolfi, Nahum Sonenberg, Nathaniel Robichaud, Luc Furic, Ola Larsson, Fred Saad, Liwei Rong
2010-06-24

Integrative genomic profiling of human prostate cancer

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Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies,Retracted: Vimentin Is a Novel Anti-Cancer Therapeutic Target; Insights from In Vitro and In Vivo Mice Xenograft Studies

Kai-Lieh Huang, Alexander J. Lazar, Mien-Chie Hung
2010-03-25

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Devon A Lawson, Andrew S Goldstein
2010-03-01

Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E
2010-01-25

Basal epithelial stem cells are efficient targets for prostate cancer initiation

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2009-11-03

Lin-Sca-1+CD49fhigh stem/progenitors are tumor-initiating cells in the Pten-null prostate cancer model
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Marianna Kruithof-de Julio, Michael M. Shen
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Inhibitor hijacking of Akt activation

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2009-05-01

Translational activation of snail1 and other developmentally regulated transcription factors by YB-1 promotes an epithelial-mesenchymal transition

Elai Davicioni
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Jonathan Weissman
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Robbie Loewith, Zachary A Knight
2009-02-01

mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice

Mark Magnuson, David M. Sabatini
2009-01-27

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The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis

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Article - wd:Q36873513

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