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Cellular and molecular mechanisms of liver injury

author

Gregory J Gores

published in: Gastroenterology

date of publication: 2008-05-01

language: English

Cites articles 118

Date

Title

Authors

2007-11-01

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

John W Blankenship
2007-11-01

Innate immune response and hepatic inflammation
2007-10-29

Celecoxib and a novel COX-2 inhibitor ON09310 upregulate death receptor 5 expression via GADD153/CHOP.
2007-08-16

Serum cytokeratin-18 fragments as quantitative markers of epithelial apoptosis in liver and intestinal graft-versus-host disease
2007-08-08

Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins

Gregory J Gores
2007-07-11

Transcriptional regulation of Bim by FoxO3A mediates hepatocyte lipoapoptosis

Gregory J Gores
2007-06-01

ER stress triggers apoptosis by activating BH3-only protein Bim

Hamsa Puthalakath, Ewa Michalak, Jennifer McKimm-Breschkin, Philippe Bouillet, Andreas Strasser, Nicholas D Huntington, Priscilla Gunn, Lorraine A O'Reilly, Priscilla Kelly
2007-07

Signal integration in the endoplasmic reticulum unfolded protein response

David Ron
2007-06-01

TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death
2007-03-12

Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage

David Adams, Abhishek Das, Elizabeth Humphreys, Pietro Lampertico, Antonio Bertoletti, Maurizia R Brunetto, Mala K Maini, Persephone Borrow
2007-01-01

Hepatitis B virus sensitizes hepatocytes to TRAIL-induced apoptosis through Bax.

Yugang Liu
2007-04-30

Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity

Gregory J Gores
2007-10-29

Serum apoptosis markers in acute liver failure: a pilot study.

Linda S. Hynan, K. Rajender Reddy
2007-01-01

Caspase-cleaved cytokeratin 18 and 20 S proteasome in liver degeneration

Stefan Hacker, Bernhard Moser, Georg A. Roth, Michael Lichtenauer, Hendrik J Ankersmit, Konrad Hoetzenecker, Peter Faybik, Wolfram Hoetzenecker
2007-11-01

Increased hepatotoxicity of tumor necrosis factor-related apoptosis-inducing ligand in diseased human liver

Michael Manns
2007-11-01

Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis.

David A. Brenner
2007-10-01

A lipidomic analysis of nonalcoholic fatty liver disease

Rebecca Baillie
2007-08-01

Oral IDN-6556, an antiapoptotic caspase inhibitor, may lower aminotransferase activity in patients with chronic hepatitis C.

Robert Gish, David A. Hecht, Nezam Afdhal
2007-09-01

Increased susceptibility to liver injury in hepatitis B virus transgenic mice involves NKG2D-ligand interaction and natural killer cells
2007-05-01

NIM811, a mitochondrial permeability transition inhibitor, prevents mitochondrial depolarization in small-for-size rat liver grafts
2007-01-17

Elevated apoptosis-associated cytokeratin 18 fragments (CK18Asp386) in serum of patients with chronic liver diseases indicate hepatic and biliary inflammation
2006-09-01

TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality

Christoph Mueller, Pascal Schneider
2006-04-06

Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis
2006-03-29

Tumor necrosis factor-induced toxic liver injury results from JNK2-dependent activation of caspase-8 and the mitochondrial death pathway

Jay H. Lefkowitch
2006-02-10

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

Michael Karin, Giovanni Solinas
2006-02-01

Apoptosis and necrosis in the liver: a tale of two deaths?

Gregory J Gores
2006-02-01

Proteasome inhibition induces hepatic stellate cell apoptosis

Gregory J Gores
2006-12-21

Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure

Richard Flavell, Roger John Davis
2006-07-01

c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity
2006-01-01

JNK1 but not JNK2 promotes the development of steatohepatitis in mice.

Jörn M Schattenberg
2006-07-01

In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease
2006-02-27

Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis

Gregory J Gores

Article - wd:Q36908855

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