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DNA damage signalling guards against activated oncogenes and tumour progression

published in: Oncogene

date of publication: 2007-12-01

language: English

main subject: DNA damage, Tumor progression

Cites articles 32

Date

Title

Authors

2007-02-15

DNA damage checkpoints: from initiation to recovery or adaptation

Jiří Lukáš, Jiří Bártek
2007-11-22

DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours

Jiří Lukáš, Jiří Bártek, Niels E. Skakkebæk, Jahn M. Nesland, Ewa Rajpert-De Meyts, Zuzana Hořejší
2007-09-01

Cellular senescence: when bad things happen to good cells

Fabrizio Daddadifagagna
2007-08-01

The common biology of cancer and ageing

Manuel Serrano, Maria A Blasco
2007-05-24

The DNA damage signaling pathway connects oncogenic stress to cellular senescence

Frédérick A Mallette, Gerardo Ferbeyre
2007-01-01

The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence

Frédérick A Mallette, Gerardo Ferbeyre
2007-05-22

Complex engagement of DNA damage response pathways in human cancer and in lung tumor progression

Paolo Nuciforo, Fabrizio Daddadifagagna
2007-06-11

The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.

Clemens A Schmitt
2007-04-22

Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.
2007-04-01

p53 in health and disease

David P. Lane, Karen Vousden
2006-11-01

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

Panagiotis Karakaidos, Evangelos Kolettas, Frederic Tort, Kasper Fugger, Claus Lindbjerg Andersen, Lars Dyrskjøt, Jiří Lukáš, Thomas Helleday, Jiří Bártek, Natalia Issaeva
2006-11-01

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

Raffaella Di Micco, Marzia Fumagalli, Patrizia Gasparini, Paolo Nuciforo, Roberta Maestro, Fabrizio Daddadifagagna
2006-08-24

ATM activation is accompanied with earlier stages of prostate tumorigenesis.
2006-01-23

E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts

Fiona M Frame
2006-02-01

Rb inactivation leads to E2F1-mediated DNA double-strand break accumulation
2006-01-23

ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.
2006-11-01

Retinoblastoma pathway defects show differential ability to activate the constitutive DNA damage response in human tumorigenesis

Jiří Lukáš, Jiří Bártek, Frederic Tort, Jiřina Bártková
2005-06-13

ATM activation in normal human tissues and testicular cancer

Jiří Lukáš, Jiří Bártek, Ewa Rajpert-De Meyts, Niels E. Skakkebæk, Jiřina Bártková
2005-04-01

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

Zuzana Hořejší, Frederic Tort, Jiří Bártek, Jahn M. Nesland
2005-10-13

The DNA damage response during DNA replication

Dana Branzei, Marco Foiani
2005-04-01

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Thomas Helleday, Nicola Curtin
2005-04-14

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Alan Ashworth, Manuela Santarosa, Ian Hickson, Christopher J Lord, Stephen P Jackson, Nuala McCabe
2005-04-01

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Panagiotis Karakaidos
2004-08-01

Functional links between telomeres and proteins of the DNA-damage response

Fabrizio d'Adda di Fagagna, Stephen P Jackson
2004-11-18

Cell-cycle checkpoints and cancer

Jiří Bártek
2004-08-01

Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time

Claudia Lukas, Jiří Lukáš, Jiří Bártek
2003-11-05

A DNA damage checkpoint response in telomere-initiated senescence

Fabrizio Daddadifagagna, Thomas von Zglinicki, Gabriele Saretzki, Stephen P Jackson
2003-03

ATM and related protein kinases: safeguarding genome integrity
2003-09-01

DNA damage foci at dysfunctional telomeres

Titia de Lange, Agata Smogorzewska
2002-12-01

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

Jiří Bártek, Jiřina Bártková
2002-05-01

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability
2001-05-17

Genome maintenance mechanisms for preventing cancer

Jan Hoeijmakers

Article - wd:Q37027188

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