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Pharmacogenetics of Gilbert's syndrome

published in: Pharmacogenomics

date of publication: 2008-06-01

Cites articles 54

Date

Title

Authors

2008-03-01

Gilbert's Syndrome and irinotecan toxicity: combination with UDP-glucuronosyltransferase 1A7 variants increases risk

Michael Manns
2007-12-01

Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substrates

Benjamin C Lewis, Peter I Mackenzie
2007-03-23

Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice
2006-09-01

Gilbert's syndrome: an overview for clinical biochemists
2006-04-01

Gilbert's syndrome: High frequency of the (TA)7 TAA allele in India and its interaction with a novel CAT insertion in promoter of the gene for bilirubin UDP-glucuronosyltransferase 1 gene

Partha P Majumder
2005-12-28

Hematologically important mutations: bilirubin UDP-glucuronosyltransferase gene mutations in Gilbert and Crigler-Najjar syndromes

Elísio Costa
2005-01-01

Molecular genetics of unconjugated hyperbilirubinemia in Taiwanese
2005-02-16

Identification and characterization of a functional TATA box polymorphism of the UDP glucuronosyltransferase 1A7 gene

Anette Fiebeler, Michael Manns
2005-06-01

Link between colorectal cancer and polymorphisms in the uridine-diphosphoglucuronosyltransferase 1A7 and 1A1 genes
2005-04-20

Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes

John Potter, Johanna W. Lampe
2005-11-18

Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: implications for drug-drug interactions.
2005-09-09

Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia.

Huldrych F Günthard, Swiss HIV Cohort Study, Enos Bernasconi, Hansjakob Furrer, Amalio Telenti
2005-08-23

In vitro inhibition of UDP glucuronosyltransferases by atazanavir and other HIV protease inhibitors and the relationship of this property to in vivo bilirubin glucuronidation
2005-12-19

Proximal HNF1 element is essential for the induction of human UDP-glucuronosyltransferase 1A1 by glucocorticoid receptor
2004-04-01

Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.

Michael Manns
2004-01-01

Correlation between the UDP-glucuronosyltransferase (UGT1A1) TATAA box polymorphism and carcinogen detoxification phenotype: significantly decreased glucuronidating activity against benzo(a)pyrene-7,8-dihydrodiol(-) in liver microsomes from subjects
2004-06-01

UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer

Atsushi Ohtsu, Kuniaki Shirao
2004

UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients

Rachel Ballard-Barbash, Shelley S. Tworoger, Peggy L. Porter, Frank Z. Stanczyk, Anne McTiernan, Cornelia M Ulrich, Kumar B. Rajan, Yutaka Yasui, Lynda McVarish, Erin J Aiello Bowles
2004-06-01

Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 (UGT1A1) and risk of breast cancer

Qiuyin Cai, Yu-Tang Gao
2004-03-01

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).
2004-01-01

The role of new agents in the treatment of colorectal cancer.

Claus-Henning Köhne
2004-04-15

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

Everett E Vokes, Mark J Ratain
2004-08-01

Relevance of different UGT1A1 polymorphisms in irinotecan-induced toxicity: a molecular and clinical study of 75 patients

Erick Gamelin, Michèle Boisdron-Celle
2003-05-01

Frequent co-occurrence of the TATA box mutation associated with Gilbert's syndrome (UGT1A1*28) with other polymorphisms of the UDP-glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians,Frequent co-occurrence of the TATA box mutation associated with Gilbert’s syndrome (UGT1A1*28) with other polymorphisms of the UDP-glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians

Matthias Schwab
2002-02

Developmental aspects of human hepatic drug glucuronidation in young children and adults
2002-06-01

Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 gene in colorectal cancer
2002-03-01

Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia
2002-12-01

Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups

Mark J Ratain, Federico Innocenti
2002-05-01

Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization
2002-09

Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
2002-09-01

Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38).

Chantal Guillemette
2001-06

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus

Ida Stephens Owens

Article - wd:Q37179528

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