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Absence of TRAM restricts Toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway

författare

James K. Liao

publicerad i: Circulation Research

utgivningsår: 2006-03-30

huvudämne: endotel, Toll-like receptors

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Datum

Titel

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2005-04-01

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Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

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Inferences, questions and possibilities in Toll-like receptor signalling

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The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

Shizuo Akira, Katsuaki Hoshino
2004-05

Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors
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Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP

Claudia Monaco, Serafim Kiriakidis
2004-02-01

IFN-alpha sensitizes human umbilical vein endothelial cells to apoptosis induced by double-stranded RNA.
2004-09-14

The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades

Harry Björkbacka, Douglas T Golenbock
2004-05-07

Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: roles of LBP and sCD14 in mediating LPS responses.
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Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways.

Kathryn J. Moore, Harry Björkbacka, Douglas T Golenbock, Kristen A Halmen
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Identification of a TLR4- and TRIF-dependent activation program of dendritic cells.

Roland Lang, Kasper Hoebe, Bruce Beutler
2004-02-05

Hyaluronan fragments stimulate endothelial recognition of injury through TLR4.

Richard Gallo
2004-08-01

Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction

Per Eriksson, Johan Frostegard
2003-11-01

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

Shizuo Akira
2003-10-01

The interferon in TLR signaling: more than just antiviral

Luke A. J. O'Neill, John A. Hamilton
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TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta

Miwa Sasai
2003-10-06

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

Eicke Latz, Douglas T Golenbock, Paula Pitha-Rowe, Katherine A. Fitzgerald, Betsy J Barnes, Daniel R Caffrey, Alberto Visintin, Brian G Monks
2003-08-01

Therapeutic targeting of Toll-like receptors for inflammatory and infectious diseases

Luke A. J. O'Neill
2003-08-14

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

Karine Crozat, Kasper Hoebe, Bruce Beutler, S. Harvey Mudd
2003-08-01

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

Eicke Latz, Tom Maniatis, Douglas T Golenbock, Anthony J Coyle
2003-04-01

Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs.

Claudine S. Bonder
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Recognition of pathogen-associated molecular patterns by TLR family
2003-05-30

Receptors involved in the oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine-mediated synthesis of interleukin-8. A role for Toll-like receptor 4 and a glycosylphosphatidylinositol-anchored protein
2003-12-29

Toll-like receptor 4 is involved in outward arterial remodeling

Paul Quax, Aryan Vink, Gerard Pasterkamp
2002-10-01

TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS.

Hugo A. Katus
2002-07-01

Toll-like receptor 4 polymorphisms and atherogenesis

Markus Reindl, Enzo Bonora
2002-10-01

In vivo evidence for a role of toll-like receptor 4 in the development of intimal lesions

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2001-12-01

Inflammation and atherothrombosis
2001-08-01

Immunopathogenesis of atherosclerosis: endotoxin accelerates atherosclerosis in rabbits on hypercholesterolemic diet

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