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PTEN: a new guardian of the genome.

author

Wen Hong Shen

published in: Oncogene

date of publication: 2008-09-01

language: English

Cites articles 105

Date

Title

Authors

2008-05-01

PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression
2008-02-11

PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a).
2008-04-07

PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex
2007-01-01

PTEN enters the nuclear age.
2007-03

A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis
2007-01-18

PTEN down regulates AP-1 and targets c-fos in human glioma cells via PI3-kinase/Akt pathway
2007-01-01

TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer

Anne-Lise Børresen-Dale, Anita Langerød, Rolf Kåresen, Stefanie S Jeffrey, Jahn M. Nesland, Ida R K Bukholm, Hongjuan Zhao
2007-01-23

PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration
2007-12-09

Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair

Johan Vallon-Christersson, Lao H Saal, Sofia Gruvberger, Håkan Olsson, Göran Jönsson, Johan Staaf, Karolina Holm, Åke Borg, Kristina Lövgren, Susan Koujak, Lorenzo Memeo, Stephen P Ethier, Isola Jorma, Hanina Hibshoosh, Ramon Parsons
2007-01-01

Essential role for nuclear PTEN in maintaining chromosomal integrity

Wen Hong Shen, Charis Eng
2007-01-12

Ubiquitination regulates PTEN nuclear import and tumor suppression

Hediye Erdjument-Bromage, Paul Tempst, Pier Paolo Pandolfi, Carlos Cordon-Cardo, Julie Teruya-Feldstein, Tom Misteli, Andrea Alimonti, Xinjiang Wang, Lloyd Trotman, Zhenbang Chen, Brett S Carver
2007-06-01

Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.

Igor Vivanco, Stephen P. Finn, Nicolaos Palaskas, Massimo Loda, Gad Getz, Todd Golub
2007-01-12

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

Hediye Erdjument-Bromage, Paul Tempst, Pier Paolo Pandolfi, Carlos Cordon-Cardo, Andrea Alimonti, Xinjiang Wang, Lloyd Trotman, Zhenbang Chen
2006-06-01

p18 Ink4c and Pten constrain a positive regulatory loop between cell growth and cell cycle control

Pier Paolo Pandolfi
2006-03-01

Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

Megan Cully
2006-12-01

Nuclear localization of PTEN is regulated by Ca(2+) through a tyrosil phosphorylation-independent conformational modification in major vault protein

Charis Eng
2006-05-07

Identification of a tumour suppressor network opposing nuclear Akt function

Pier Paolo Pandolfi, Carlos Cordon-Cardo, Andrea Alimonti, Lloyd Trotman, Jason A Koutcher, Pier Paolo Scaglioni
2006-01-01

PTEN autoregulates its expression by stabilization of p53 in a phosphatase-independent manner

Charis Eng
2006-08-01

The relationship between microsatellite instability and PTEN gene mutations in endometrial cancer

Juan Carlos Díaz-Chico, Manuel Perucho
2005-08-04

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Carlos Cordon-Cardo, Pier Paolo Pandolfi, Lloyd Trotman, Zhenbang Chen, Hui-Kuan Lin, David W. Shaffer, Zohar A Dotan, Masaru Niki, Jason A Koutcher
2005-05-01

Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) has nuclear localization signal-like sequences for nuclear import mediated by major vault protein

Charis Eng
2005-10-01

PTEN enters the nucleus by diffusion
2005-07-01

Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation
2005-04-21

PTEN: a novel anti-oncogenic function independent of phosphatase activity

Frank B Furnari, Ronald A. DePinho
2005-02-01

Lack of PTEN sequesters CHK1 and initiates genetic instability

Atish D Choudhury, Zbigniew Gaciong, Megan Keniry
2005-07-01

Life, death, and ubiquitin: taming the mule

Moshe Oren
2005-07-13

Different splicing defects lead to differential effects downstream of the lipid and protein phosphatase activities of PTEN

Charis Eng
2005-07-03

PTEN loss inhibits CHK1 to cause double stranded-DNA breaks in cells
2004-01-27

Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten

Vuk Stambolic, Lothar Hennighausen, Ming-Sound Tsao
2004-04-16

PTEN regulates Mdm2 expression through the P1 promoter
2004-09-01

PTEN can inhibit in vitro organotypic and in vivo orthotopic invasion of human bladder cancer cells even in the absence of its lipid phosphatase activity

Michael A Harding, Christopher Moskaluk
2004-08-15

PTEN function: how normal cells control it and tumour cells lose it

Nick R. Leslie

Article - wd:Q37270432

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