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Genome-wide association studies identify genetic loci for low von Willebrand factor levels

author

Abbas Dehghan

2000 -

Caroline Hayward

2000 -

Pim van der Harst

Lorna M. Lopez

Ian Deary

1954 -

Stella Trompet

Aaron R. Folsom

Albert Hofman

1951 -

Bruce M. Psaty

Wendy L McArdle

Jacqueline C M Witteman

J Wouter Jukema

David J Stott

published in: European Journal of Human Genetics

date of publication: 2015-10-21

main subject: genome-wide association study

Cites articles 45

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CLEC4M and STXBP5 gene variations contribute to von Willebrand factor level variation in von Willebrand disease

Aaron Isaacs, Jeroen C J Eikenboom
2014-06-11

The ufm1 cascade
2012-12-24

Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association

Anjali A Sharathkumar, David Ginsburg, Anne M. Molloy, Joan Bailey-Wilson, James L. Mills, Alexander F Wilson, Caitlin P McHugh, Daniel B Mirel
2012-07-06

Effect of genetic variation in STXBP5 and STX2 on von Willebrand factor and bleeding phenotype in type 1 von Willebrand disease patients

Yvonne V Sanders
2012-04-01

Genetic determinants of von Willebrand factor plasma levels and the risk of stroke: the Rotterdam Study

M. Arfan Ikram, Albert Hofman, Jacqueline C M Witteman, Monique Breteler
2011-10-06

Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses

Naveed Sattar, Stella Trompet, Eline Slagboom, Rudi Westendorp, J Wouter Jukema, David J Stott, Anton J M de Craen, Iris Postmus, Frank M Sacks, PROSPER Study Group, Ian Ford
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Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort

Eric Boerwinkle, Aaron R. Folsom, Christie M. Ballantyne
2011-05-01

Genetic determinants of von Willebrand factor levels and activity in relation to the risk of cardiovascular disease: a review
2010-12-01

Effect of genetic variations in syntaxin-binding protein-5 and syntaxin-2 on von Willebrand factor concentration and cardiovascular risk

Don Poldermans
2010-03-18

Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time

Peter M. Visscher, Lorna M. Lopez, Alan J. Gow, David J. Porteous, Ian Deary, Dave Liewald, John M Starr, Sarah E Harris, Gordon Matthew Lowe
2010-03-15

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium

Abbas Dehghan, Nicole Soranzo, Caroline Hayward, Frances M. Williams, James S. Pankow, André Uitterlinden, Igor Rudan, Veronique Vitart, Eric Boerwinkle, Anders Mälarstig, James F. Wilson, Maria Sabater-Lleal, Mary Cushman, Martin G Larson, Jerome I Rotter, Albert Hofman, Sekar Kathiresan, Anders Hamsten, James B. Meigs, Wolfgang Koenig, Annette Peters, Bruce M. Psaty, Wendy L McArdle, Joshua C Bis, Thomas Lumley, Jacqueline C M Witteman, Harry Campbell, Tim Spector, David P Strachan, Kerri L Wiggins, Geoffrey H Tofler, John G Peden, Aaron R. Folsom, Christopher J O'Donnell, Ming-Huei Chen, Barbara McKnight, Nena Aleksic, Edwin G Bovill
2010-10-12

Variation in the von Willebrand factor gene is associated with von Willebrand factor levels and with the risk for cardiovascular disease

Aaron Isaacs, Cornelia M. van Duijn
2009-02

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts

Vilmundur Gudnason, André Uitterlinden, Bruce M. Psaty, Eric Boerwinkle, Kathryn L. Lunetta, Jerome I Rotter, Tamara B. Harris, Aaron R. Folsom, Jacqueline C M Witteman
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Low von Willebrand factor: sometimes a risk factor and sometimes a disease
2008-09

Runs of homozygosity in European populations

Igor Rudan, Veronique Vitart, Ozren Polašek, Caroline Hayward, Albert Tenesa, Andrew K MacLeod, James F. Wilson, Anne-Louise Leutenegger, Malcolm G. Dunlop, Harry Campbell, Susan M Farrington, Sarah H Wild, Ruth McQuillan, Christopher Franklin, Marijana Peričić Salihović, Lovorka Barac-Lauc, Nina Smolej-Narancic, Branka Janićijević, Pavao Rudan, Alan F Wright
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Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women

Mark D. Kellogg, Guillaume Paré, Nader Rifai, Paul Ridker, Daniel I Chasman
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The ligand-binding profile of HARE: hyaluronan and chondroitin sulfates A, C, and D bind to overlapping sites distinct from the sites for heparin, acetylated low-density lipoprotein, dermatan sulfate, and CS-E.
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von Willebrand factor in cardiovascular disease: focus on acute coronary syndromes

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The Rotterdam Study: objectives and design update

Henning Tiemeier, Cornelia M. van Duijn, André Uitterlinden, Albert Hofman, Jacqueline C M Witteman, Monique Breteler
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Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study

Sekar Kathiresan, Qiong Yang
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Imputation-based analysis of association studies: candidate regions and quantitative traits

Bertrand Servin
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A new multipoint method for genome-wide association studies by imputation of genotypes
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The mutational spectrum of type 1 von Willebrand disease: Results from a Canadian cohort study
2007-01-25

Lifecourse influences on health among British adults: effects of region of residence in childhood and adulthood

Meena Kumari, Gary J. Macfarlane, Jugnoo S. Rahi, Alicja R Rudnicka, Bryan Rodgers
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Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor

Dominique Meyer, J. Evan Sadler
2006-04-14

Activation of endoplasmic reticulum stress response during the development of ischemic heart disease
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The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study
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Phenotype and genotype of a cohort of families historically diagnosed with type 1 von Willebrand disease in the European study, Molecular and Clinical Markers for the Diagnosis and Management of Type 1 von Willebrand Disease (MCMDM-1VWD)

Anne C Goodeve, Jeroen C J Eikenboom, Javier Batlle, Mohammad Hashemi Soteh, Reinhard Schneppenheim
2005-11-01

Regulation of Weibel-Palade body exocytosis

Article - wd:Q37351431

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