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Synthetic lethality between PAXX and XLF in mammalian development

author

Gabriel Balmus

Anneliese O Speak

Ludovic Deriano

Andrew N Blackford

Stephen P Jackson

published in: Genes & Development

date of publication: 2016-10-01

Cites articles 29

Date

Title

Authors

2016-09-06

PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line

Richard Frock
2016-02-02

RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair

Valentine Murigneux, Patrick Revy, Jean-Pierre de Villartay, Ludovic Deriano
2016-01-01

Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome Engineering

Jennifer Doudna
2016-12-17

Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice
2016-09-02

Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination

Hélène Lenden Hasse, Gabriel Balmus, Joy J Bianchi, Bernardo Reina San-Martin, Stephen P Jackson, Ludovic Deriano
2015-06

XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair
2015

Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

Dongyi Xu, Shan Zha
2015-01-09

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

Satpal Jhujh, Qian Wu, Viji M. Draviam, Carol V. Robinson, Stephen P Jackson
2014-12-31

A high-throughput in vivo micronucleus assay for genome instability screening in mice

Natasha A Karp, Stephen P Jackson
2014-03-26

One ring to bring them all--the role of Ku in mammalian non-homologous end joining
2014-03-11

The spatial organization of non-homologous end joining: from bridging to end joining

Qian Wu, Tom Blundell
2014-03-11

The clinical impact of deficiency in DNA non-homologous end-joining

Andrew R Gennery
2012-07-01

Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase

Alexander Loewer, Ran Kafri
2012-02-21

Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development

Shan Zha
2012-01-30

Functional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair

Valentyn Oksenych
2011-01-13

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks

Valentyn Oksenych, Shan Zha
2009-10-22

The DNA-damage response in human biology and disease

Stephen P Jackson, Jiří Bártek
2009-11-04

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
2008-09-05

Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination

Shan Zha
2006-01-27

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

Stephen P Jackson
2006-01-27

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

Jean-Pierre de Villartay, Alain Fischer, Laurent Malivert, Patrick Revy, Anne Durandy
2002-12-05

The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants
2000-03-14

Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice
1998-12-23

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis
1998-11-12

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV
1997-09-01

Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo

Michel C. Nussenzweig
1996-08-01

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

Dae-Sik Lim
1996-08-01

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

Michel C. Nussenzweig
1996-07-12

Atm-deficient mice: a paradigm of ataxia telangiectasia

Francis Collins

Article - wd:Q37383233

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