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The challenge of finding a cure for HIV infection

author

David M. Margolis

Roger J. Pomerantz

published in: Science

date of publication: 2009-03-01

language: English

main subject: HIV

Cites articles 38

Date

Title

Authors

2008-01-01

Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system

Ronald Ellis, Scott Letendre, Igor Grant, Susan Morgello, Charter Group, John Allen McCutchan, Benjamin B Gelman, Justin C McArthur, Jennifer Marquie-Beck, Brookie M Best, Edmund Capparelli, Ann C Collier
2008-03-10

Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy

Frank Maldarelli, John Coffin, John W Mellors, Sarah Palmer, Ann Wiegand
2008-04-01

Hexamethylbisacetamide and disruption of human immunodeficiency virus type 1 latency in CD4(+) T cells.

David M. Margolis
2008-01-15

Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice

Daniel A Powell, Paul W. Denton, Jacob D Estes, Florence A Othieno, Deborah A Payne, Ashley T Haase
2008-06-01

Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells

David M. Margolis, Joseph J Eron, John Coffin, Sarah Palmer, Ann Wiegand
2007-01-01

Cardiovascular risks of antiretroviral therapies

Pablo Tebas
2007-04-01

ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia

Michael A. Polis, Frank Maldarelli, John Coffin, John W Mellors, Sarah Palmer, Catherine Rehm, Ann Wiegand
2007-07-20

Regulation of HIV-1 latency by T-cell activation

Samuel A Williams
2007-08-01

c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter

David M. Margolis
2007-11-15

CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency
2007-09-30

Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes
2007-07-30

HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR

Fatah Kashanchi
2007-02-01

Experimental approaches to the study of HIV-1 latency

Megan Wind-Rotolo, Robert F. Siliciano, Janet D Siliciano
2006-06-01

The survival benefits of AIDS treatment in the United States

Rochelle P. Walensky, Elena Losina, Milton Weinstein, Kenneth A. Freedberg, A. David Paltiel, Paul E Sax, Bruce R Schackman
2006-08-01

Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study.

Caroline Sabin, Nina Friis-Møller, Antonella d'Arminio Monforte, Stéphane De Wit, François Dabis, Wafaa El-Sadr, Bruno Ledergerber, Andrew N Phillips, Jens Lundgren, Ole Kirk, Peter Reiss
2006-07

Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells

Megan Wind-Rotolo, Yi Liu-Chittenden, Claus O. Wilke, Stuart C. Ray, Thomas C. Quinn, Robert F. Siliciano, Janet D Siliciano, Deborah Persaud
2006-08-01

Controlling the elongation phase of transcription with P-TEFb

David H Price
2006-05-01

Hexamethylbisacetamide remodels the human immunodeficiency virus type 1 (HIV-1) promoter and induces Tat-independent HIV-1 expression but blunts cell activation

David M. Margolis
2006-07-01

Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells

Robert F. Siliciano
2006-10-22

Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.

Paul W. Denton
2005-12-01

NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation

Eric Verdin
2005-10-01

Molecular mechanisms of HIV-1 proviral latency
2005-01-01

IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART.

Giuseppe Nunnari, Roger J. Pomerantz
2005-03-29

Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1.

Huldrych F Günthard, Diane Havlir, Susan J Little
2004-07-28

Prostratin antagonizes HIV latency by activating NF-kappaB

David Fenard, Eric Verdin, Samuel A Williams
2003-04-08

Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence

Huldrych F Günthard, Davey Smith, Andrew J Leigh Brown
2003-04-01

Resting CD4+ T lymphocytes but not thymocytes provide a latent viral reservoir in a simian immunodeficiency virus-Macaca nemestrina model of human immunodeficiency virus type 1-infected patients on highly active antiretroviral therapy

Robert F. Siliciano, Joseph B Margolick, Lucy M Carruth
2002-10-29

Intensification and stimulation therapy for human immunodeficiency virus type 1 reservoirs in infected persons receiving virally suppressive highly active antiretroviral therapy

Joseph DeSimone, Roger J. Pomerantz
2001-07-01

Prevalence and predictive value of intermittent viremia with combination hiv therapy

Huldrych F Günthard, Ann C Collier
2001-11-01

Prostratin: activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART.
2000-08-01

Residual HIV-RNA levels persist for up to 2.5 years in peripheral blood mononuclear cells of patients on potent antiretroviral therapy

Huldrych F Günthard
2000-08-01

The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1.

Article - wd:Q37407598

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