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LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.

auteur·ice

Hee-Woong Lim

Vasumathi Kameswaran

Kyoung-Jae Won

Klaus H. Kaestner

publié dans: Journal of Clinical Investigation

date de publication: 2016-12-12

langue: anglais

Articles cités 83

Date

Titre

Auteur·ices

2016-03-16

PDX1 and ISL1 differentially coordinate with epigenetic modifications to regulate insulin gene expression in varied glucose concentrations.
2015-12-29

Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes

Domenico Accili, Lorella Marselli
2015-11-01

Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells
2015-10-23

SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic β-Cell Target Genes
2015-09-02

Postnatal β-cell maturation is associated with islet-specific microRNA changes induced by nutrient shifts at weaning

Scot J Matkovich, Romano Regazzi, Cécile Jacovetti, Claudiane Guay
2015-07-15

ISL-1 promotes pancreatic islet cell proliferation by forming an ISL-1/Set7/9/PDX-1 complex
2015-06-27

Active promoters give rise to false positive 'Phantom Peaks' in ChIP-seq experiments

Peter B Becker, Dhawal S Jain, Tobias Straub
2015-04-27

Tshz1 Regulates Pancreatic β-Cell Maturation
2015-01-20

Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program
2015-03-01

Pancreatic β-cell identity, glucose sensing and the control of insulin secretion

David J Hodson, Guy A. Rutter, Timothy J Pullen, Aida Martinez-Sanchez
2015-08-27

Aging-Dependent Demethylation of Regulatory Elements Correlates with Chromatin State and Improved β Cell Function

Benjamin Glaser, Dirk Schübeler
2015-08-27

The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors

Mario Looso, Wilfred F J van IJcken, Eric Soler, Luca Caputo, Petros Kolovos, Thomas Braun, Gergana Dobreva
2014-01-01

Characterization of mice expressing Ins1 gene promoter driven CreERT recombinase for conditional gene deletion in pancreatic β-cells
2014-10-01

Generation of functional human pancreatic β cells in vitro

Jeffrey R Millman, Quinn P Peterson, Douglas Melton, Felicia W. Pagliuca
2014-11

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

Jennifer E Bruin, Yu Hsuan Carol Yang, James D Johnson
2014-09-08

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

Jones K Ofori, Francesca Finotello, Joao Fadista, Rashmi B Prasad, Inês G Mollet, Jonathan Lou S Esguerra, Ola Hansson, Lena Eliasson, Leif Groop
2014-08-01

Reactivation of developmentally silenced globin genes by forced chromatin looping

Ivan Krivega, Laura Breda, Irene Motta, Philip D Gregory, Stefano Rivella
2014-07-15

Islet-1 Is essential for pancreatic β-cell function

Chad S. Hunter
2014-06-23

LIM-homeodomain transcription factor Isl-1 mediates kisspeptin's effect on insulin secretion in mice
2014-05-29

Role of LDB1 in the transition from chromatin looping to transcription activation

Ivan Krivega, Ryan K Dale
2014-04

Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes

Anthony P Barnes
2014-02-10

Differentiated human stem cells resemble fetal, not adult, β cells

Sinisa Hrvatin, Colm O'Donnell, Francis Deng, Jeffrey R Millman, Douglas Melton
2014-02-01

Pdx1 maintains β cell identity and function by repressing an α cell program

Tarjinder Singh, Helena Edlund
2014-01-12

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

Lorenzo Pasquali, Kyle J Gaulton, Santiago A Rodríguez-Seguí, Loris Mularoni, Irene Miguel-Escalada, İldem Akerman, Juan J Tena, Carlos Gómez-Marín, Martijn van de Bunt, François Pattou, Lorenzo Piemonti, Anna Gloyn, Philippe Ravassard, José Luis Gómez-Skarmeta, Mark McCarthy, Jorge Ferrer
2014-04-17

Pancreatic β cell dedifferentiation in diabetes and redifferentiation following insulin therapy
2013-11-27

Ldb1 complexes: the new master regulators of erythroid gene transcription
2013-10

The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells

Andhira Vieira, Noémie Druelle, Patrick Collombat, Damien Ambrosetti, Philippe Ravassard
2013-09-12

Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells
2013-07-21

Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity

Esteban O. Mazzoni, Shaun Mahony, Stéphane Nédélec
2013-07-01

Inactivation of specific β cell transcription factors in type 2 diabetes
2013-07-11

Structural Basis for LMO2-Driven Recruitment of the SCL:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets

Olga Platonova, Erika J Mancini, Kamel El Omari, Paresh Vyas
2013-04-24

No evidence for β cell neogenesis in murine adult pancreas

Xiangwei Xiao, Krishna Prasadan

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