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An emerging role of mTOR in lipid biosynthesis.

author

David M. Sabatini

1968 -

published in: Current Biology

date of publication: 2009-12-01

language: English

Cites articles 48

Date

Title

Authors

2009-07-10

Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway
2009-06-03

mTOR complex 2 in adipose tissue negatively controls whole-body growth

Johan Auwerx
2009-06-12

Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

Alexander Gray, Dario Alessi
2009-03-03

Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1
2009-02-01

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans

Justine A Melo, Christopher E Carr, Gary Ruvkun
2009-02-10

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

Robbie Loewith, Zachary A Knight
2009-03-20

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
2009-02-01

A new player in the orchestra of cell growth: SREBP activity is regulated by mTORC1 and contributes to the regulation of cell and organ size

Almut Schulze
2009-04-21

New insights into mTOR signaling: mTORC2 and beyond.

Dario Alessi, Laura R Pearce
2008-09-12

Thematic Review Series: Glycerolipids. Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism

Karen Reue
2008-09

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

Almut Schulze, Megan Cully
2008

Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice

Shen Yon Toh, Yinxin Zhang, Zilong Wen, Hongyuan Yang
2008-02-23

Thematic review series: sphingolipids. New insights into sphingolipid metabolism and function in budding yeast
2008-02-01

Regulation of ceramide biosynthesis by TOR complex 2.
2008-10-16

Lipin1 is a key factor for the maturation and maintenance of adipocytes in the regulatory network with CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma 2

Yong Ho Ahn
2008-11-01

Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration

Johan Auwerx
2007-10-01

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

Javier A Menendez
2007-07-01

Defining the role of mTOR in cancer

David M. Sabatini
2007-06-29

AKT/PKB signaling: navigating downstream

Lewis C. Cantley
2007-03-05

SREBP-1c transcription factor and lipid homeostasis: clinical perspective

Pascal Ferré, Fabienne Foufelle
2007-02-01

Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2

Nahum Sonenberg, Katherine Cianflone
2007-09-01

Role of the PI3-kinase/mTor pathway in the regulation of the stearoyl CoA desaturase (SCD1) gene expression by insulin in liver

Daniel Mauvoisin, Catherine Mounier
2007-11-01

The mammalian target of rapamycin regulates lipid metabolism in primary cultures of rat hepatocytes

German Perdomo
2006-12

Adipocyte differentiation from the inside out
2006-10-01

(Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms
2006-04-06

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

David M. Sabatini
2005-05-01

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
2005-01-06

Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c

Pascal Ferré, Fabienne Foufelle
2005-09-01

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP.

Julian Downward, Almut Schulze
2004-11-01

Obesity and hepatocellular carcinoma
2004-08-11

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

M Joaquin, George Thomas
2004-06

Adipose tissue as an endocrine organ

Jeffrey Scott Flier

Article - wd:Q37641438

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