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Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination

author

John Miles

David A Price

published in: Immunology & Cell Biology

date of publication: 2011-02-08

main subject: pathogenesis, bias

Cites articles 139

Date

Title

Authors

2010-07-05

Allelic polymorphism in the T cell receptor and its impact on immune responses

Jamie Rossjohn, Lars Kjer-Nielsen, Stephanie Gras, James McCluskey, Rebekah M Brennan, Michelle A Neller, Lucy C. Sullivan, Scott R Burrows, Andrew G Brooks, Rajiv Khanna, Anthony W. Purcell, John J Miles, Zhenjun Chen, Melissa E Bell
2010-07-16

Human T-cell memory consists mainly of unexpanded clones

Rene van Lier, Frank Baas, Niek de Vries, Barbera D.C. van Schaik, Paul P Tak, Aeilko H Zwinderman, Marja E Jakobs, Antoine van Kampen, Paul L Klarenbeek
2010-01-04

High throughput sequencing reveals a complex pattern of dynamic interrelationships among human T cell subsets
2010-09-01

Overlap and effective size of the human CD8+ T cell receptor repertoire
2010-02-05

Public TCR use by herpes simplex virus-2-specific human CD8 CTLs

David M Koelle
2010-08-16

IL-10 restricts memory T cell inflation during cytomegalovirus infection

Ian R. Humphreys, Kristin Ladell, David A Price, Emma Gostick
2010-12-06

Persistent survival of prevalent clonotypes within an immunodominant HIV gag-specific CD8+ T cell response

Kristin Ladell, David A Price, Cynthia Mee Ling Munier, Miles Davenport
2010-05-03

Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion

Peter C. Doherty, Nicole L La Gruta, Sophie A Valkenburg, Katherine Kedzierska, Paul G. Thomas, Stephen J. Turner
2010-10-25

Convergent recombination shapes the clonotypic landscape of the naive T-cell repertoire

Kylie M. Quinn, Miles Davenport, David A Price
2010-07-16

Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition

David K. Cole, Emily Edwards, John Miles, Kristin Ladell, Mark Peakman, David A Price, Andrew K Sewell, Emma Gostick
2010-08-12

Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska, Carole Guillonneau, Paul G. Thomas, Stephen J. Turner, Anthony W. Purcell, Peter C. Doherty, Nicole L La Gruta, Sophie A Valkenburg
2010-02-01

Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity

Martin Rowe
2009-06-18

Profiling the T-cell receptor beta-chain repertoire by massively parallel sequencing

Brad H Nelson
2009-04-06

Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection

Pratip K. Chattopadhyay, Miles Davenport, David A Price, David I Watkins, Mario Roederer, Martha Nason, Emma Gostick
2009-09-28

Fine structural variations of alphabetaTCRs selected by vaccination with natural versus altered self-antigen in melanoma patients
2009-03-24

Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients

Luigi Caimi
2009-04-23

Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection

Philippa Marrack, Laurent Gapin, James P Scott-Browne, John Kappler, Janice White
2009-10-02

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

George F. Gao, David K. Cole, Andrew K Sewell, John J Miles, David A Price, Emma Gostick
2009-07-01

Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope

Bernard Malissen, Stephanie Gras, Adrien Kissenpfennig, Nicole Thielens
2009-12-11

The immune response during acute HIV-1 infection: clues for vaccine development

Barton Haynes, Andrew James McMichael, Georgia D. Tomaras, Persephone Borrow
2008-03-01

The molecular basis for public T-cell responses?

Miles Davenport, David A Price
2008-04-15

Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection

Jamie Rossjohn, Stephanie Gras, James McCluskey, Julia K Archbold, Scott R Burrows, Rajiv Khanna, John Miles, Fleur E Tynan
2008-08-01

The role of production frequency in the sharing of simian immunodeficiency virus-specific CD8+ TCRs between macaques
2008-11-01

Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+ T cells with peptide-major histocompatibility complex class I tetramers

Kristin Ladell, Phillip Scheinberg, Pratip K. Chattopadhyay, Andrew K Sewell, David A Price, Mario Roederer, Emma Gostick
2008-09-22

Distinct sets of alphabeta TCRs confer similar recognition of tumor antigen NY-ESO-1157-165 by interacting with its central Met/Trp residues

Laurent Derré, Olivier Michielin
2008-01-01

Public T cell receptor beta-chains are not advantaged during positive selection.

Freda K. Stevenson, Elizabeth Simpson, Anna Furmanski
2008-02

The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domain

Andrew James McMichael, Guillaume Stewart-Jones, Yvonne Jones
2008-12-09

Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy

Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska, Carole Guillonneau, Peter C. Doherty, Anthony W. Purcell, Stephen J. Turner, Richard Webby
2008-12-01

TCR beta-chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV

Kristin Ladell
2008-10-01

Despite biased TRBV gene usage against a dominant HLA B57-restricted epitope, TCR diversity can provide recognition of circulating epitope variants
2008-05-01

Contribution of TCR-beta locus and HLA to the shape of the mature human Vbeta repertoire
2008-01-01

Cytomegalovirus immune evasion

Article - wd:Q37837483

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