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Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemia.

автор

Maria Teresa Scupoli

опубліковано в: Expert Review of Hematology

дата публікації: 2012-06-01

основна тема: лімфоцити, лейкоз

Cites articles 63

Дата

Заголовок

Автори

2012-01-01

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks
2012-03-01

Inhibiting B-cell receptor signaling pathways in chronic lymphocytic leukemia
2011-08-03

B-cell receptor signaling in chronic lymphocytic leukemia

Freda K. Stevenson, Graham Packham, Andrew Davies
2011-11-15

Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells

Freda K. Stevenson, Graham Packham
2011-06

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
2011-03-21

Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765.

John C Byrd, Kristie A Blum, Jeffrey A Jones, Samantha M Jaglowski, Asha Ramanunni, Sarah E M Herman, Erin Hertlein
2011-12-16

The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo

William G Wierda, Susan O'Brien, Michael J. Keating, Jan A Burger, Kumudha Balakrishnan, Nicholas Chiorazzi
2011-07-29

The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia

Hagop Kantarjian, William G Wierda, Susan O'Brien, Michael J. Keating, Jan A Burger, Julia Hoellenriegel, Mariela Sivina, Neill A Giese, Langdon L Miller, Brian J Lannutti
2010-10-12

The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia

Maryalice Stetler-Stevenson, Stefania Pittaluga, Wyndham H. Wilson
2010-09-09

The role of the B-cell receptor in the pathogenesis of chronic lymphocytic leukaemia

Freda K. Stevenson
2010-04-01

Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia

Julie M Vose, Ann S LaCasce, Margaret A Shipp
2010-07-06

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

Douglas H Thamm
2010-03-22

Safety, pharmacokinetics, and preliminary clinical activity of inotuzumab ozogamicin, a novel immunoconjugate for the treatment of B-cell non-Hodgkin's lymphoma: results of a phase I study

Gregor Verhoef, Mitchell Smith, Luis E. Fayad, Martin Dreyling
2009-09-01

The lymphatic tissue microenvironments in chronic lymphocytic leukemia: in vitro models and the significance of CD40-CD154 interactions
2009-01-05

Rel a is an independent biomarker of clinical outcome in chronic lymphocytic leukemia.

Robert K Hills
2008-12-18

Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells

Dimitar Efremov, Valeria Berno
2008-01-28

The NF-kappaB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target

Paul Brennan
2008-02-21

Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy

Paolo Ghia, Cristina Scielzo, Marta Muzio
2008-11-02

Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling

Randall J. Brezski
2008-05-16

BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells.

Monica Messina, Francesca Romana Mauro
2008-08-15

Overexpression of TOSO in CLL is triggered by B-cell receptor signaling and associated with progressive disease.

Christian P. Pallasch, Michael Hallek, Alfred Ultsch
2008-11-01

Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial

Rubén Burgos-Vargas, Arthur Kavanaugh
2008-12-01

Microenvironmental influences in chronic lymphocytic leukaemia: the role of antigen stimulation

Paolo Ghia
2007-10-01

Calcium signalling and cell-fate choice in B cells
2007-08-22

Src family kinases: regulation of their activities, levels and identification of new pathways

Evan Ingley
2007-10-10

The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

Giuseppe Leone, Dimitar Efremov
2007-01-01

Bruton's tyrosine kinase and phospholipase Cgamma2 mediate chemokine-controlled B cell migration and homing

Sabine Middendorp, Janine M van Gils, Marcel Spaargaren
2006-04-17

Silencing of autoreactive B cells by anergy: a fresh perspective

John Cambier
2006-07-01

Survival response to B-cell receptor ligation is restricted to progressive chronic lymphocytic leukemia cells irrespective of Zap70 expression

Rémi Letestu, Nathalie Chevallier
2006-08-31

R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation
2005-01-18

Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells
2005-02-22

Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells.

Giuseppe Leone, Dimitar Efremov

Стаття - wd:Q38025162

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