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Genomic instability and colon carcinogenesis: from the perspective of genes

published in: Frontiers in Oncology

date of publication: 2013-05-21

main subject: carcinogenesis

Cites articles 144

Date

Title

Authors

2013-02-01

Replication stress links structural and numerical cancer chromosomal instability

Jiří Bártek, Eva Gronroos, Axel Behrens, Enric Domingo, Charles Swanton, Thomas Helleday, Ian Tomlinson, Sally M Dewhurst, David Endesfelder, Nnennaya Kanu, Rebecca Burrell, Maik Kschischo, Sarah E McClelland
2013-01-15

SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer

Robert N Jorissen, Oliver Sieber, Peter Gibbs, Nicholas J. Hawkins, Jayesh Desai, Robyn Ward, John M Mariadason, Antony W Burgess, Dmitri Mouradov, Nicholas Fleming, Anuratha Sakthianandeswaren, Michelle Palmieri, Cary Tsui, Lara Lipton, Robert L. Strausberg
2012-12-27

Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation

Tobias Wijshake
2012-12-19

Qualitative and quantitative expression status of the human chromosome 20 genes in cancer tissues and the representative cell lines

Zhe Ren, Cheng Chang
2012-12-07

Aneuploidy causes proteotoxic stress in yeast

Angelika Amon
2012-12-03

Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression

Andrew M. Harrison, Jan M van Deursen
2012-11-25

Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function

Lewis C. Cantley, Jason W. Locasale
2012

HSP90 inhibitors for cancer therapy and overcoming drug resistance,HSP90 Inhibitors for Cancer Therapy and Overcoming Drug Resistance

Shanu Modi
2012-02-01

Haploinsufficiency of SGO1 results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis

Yixin Yao, Wei Dai
2012-01-01

Hsp90 molecular chaperone inhibitors: are we there yet?

Paul Workman, Len Neckers
2012-01-01

Beyond trastuzumab: novel therapeutic strategies in HER2-positive metastatic breast cancer
2012-01-18

DNA breaks and chromosome pulverization from errors in mitosis
2012-04-30

Chromosomal instability (CIN) phenotype, CIN high or CIN low, predicts survival for colorectal cancer

Soichiro Ishihara
2011-12-14

Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction

James D. Orth, Alexander Loewer
2011-11-04

p53 dependent centrosome clustering prevents multipolar mitosis in tetraploid cells

Dr Mian Wu
2011-11-02

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

Tobias Wijshake, Nathan K. LeBrasseur
2011-06-06

Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation
2011-02-01

Identification of aneuploidy-selective antiproliferation compounds

Angelika Amon
2011-09-01

Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations

René H. Medema, Aniek Janssen, Karoly Szuhai
2011-07-10

Cleavage of cohesin rings coordinates the separation of centrioles and chromatids

Laura Schöckel, Martin M Möckel, Dominik Boos
2010-10-01

A 12-gene genomic instability signature predicts clinical outcomes in multiple cancer types
2010-12-01

Getting through anaphase: splitting the sisters and beyond

Kim Nasmyth, Raquel A. Oliveira
2010-10-01

Destabilizing aneuploidy by targeting cell cycle and mitotic checkpoint proteins in cancer cells
2010-08-13

Gene dysregulations driven by somatic copy number aberrations-biological and clinical implications in colon tumors: a paper from the 2009 William Beaumont Hospital Symposium on Molecular Pathology
2010-06-08

Low molecular weight cyclin E overexpression shortens mitosis, leading to chromosome missegregation and centrosome amplification

Khandan Keyomarsi, Kelly K Hunt
2010-05-27

Chromosome missegregation causes colon cancer by APC loss of heterozygosity

Jan M van Deursen, Darren J Baker
2010-03-01

Mechanisms of chromosomal instability

Samuel F Bakhoum, Duane A Compton
2010-02-25

Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos.

Laura Senovilla, Guido Kroemer, Lorenzo Galluzzi, Mickaël Michaud, Oliver Kepp, Ilio Vitale, Alfredo Criollo, Gwenola Manic, Sonia Vivet, Lisa Nanty, Maria Castedo, Mohamed Jemaà, Santiago Rello-Varona, Didier Métivier, Nicolas Tajeddine, Nicholas Joza, Alexander Valent
2010-02-01

Proliferation of aneuploid human cells is limited by a p53-dependent mechanism

Duane A Compton
2010-02-01

Mitotic chromosomal instability and cancer: mouse modelling of the human disease

Rocio Sotillo, Juan Manuel Schvartzman
2010-02-21

Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal

Rocio Sotillo
2010-06-01

Molecular causes for BUBR1 dysfunction in the human cancer predisposition syndrome mosaic variegated aneuploidy

Nazneen Rahman, Saskia J E Suijkerbuijk, Geert Kops

Article - wd:Q38111773

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