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Recent genetic findings in schizophrenia and their therapeutic relevance

publicat în: Journal of Psychopharmacology

Data de publicare: 2014-10-14

Limbă: limba engleză

Subiectul principal: schizofrenie, Neuroleptic

Citează articole 165

Dată

Title

Autori

2014-09-16

What causes aberrant salience in schizophrenia? A role for impaired short-term habituation and the GRIA1 (GluA1) AMPA receptor subunit

David J. Sanderson, Christopher Barkus, Mark E Walton, David M Bannerman
2014-07-24

Biological insights from 108 schizophrenia-associated genetic loci

Hannelore Ehrenreich, Richard Bruggeman, Ingrid Agartz, Tune H Pers
2014-07-01

Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases

Klaus-Armin Nave
2014-09-01

Effects of schizophrenia risk variation in the NRG1 gene on NRG1-IV splicing during fetal and early postnatal human neocortical development

Clare Paterson, Amanda J Law
2014-05-27

Large-scale genomics unveils the genetic architecture of psychiatric disorders

Peter M Visscher, Jacob Gratten, Matthew C Keller, Naomi R. Wray
2014-04-24

Guidelines for investigating causality of sequence variants in human disease

David Dimmock, Heidi L. Rehm, Jay Shendure, Russ Altman, Stilianos Antonarakis, Jeffrey C Barrett, Chris Gunter, Suzanne M. Leal
2014-06-01

Differential effects of common variants in SCN2A on general cognitive ability, brain physiology, and messenger RNA expression in schizophrenia cases and control individuals

Joseph H Callicott, Daniel R. Weinberger, Richard E Straub, Bhaskar Kolachana, Dan Rujescu
2014-04-01

The synapse in schizophrenia

Michael C O'Donovan, Andrew Pocklington
2014-03-27

Unlocking the treasure trove: from genes to schizophrenia biology

W. Richard McCombie, Aiden Corvin
2014-03-01

The emerging roles of TCF4 in disease and development

Marc P Forrest, Matthew J Hill
2014-02-26

Genetic modifiers and subtypes in schizophrenia: investigations of age at onset, severity, sex and family history

Patrick F Sullivan, Sarah E Bergen, Douglas M. Ruderfer, Aiden Corvin, Jordan W Smoller, Stephan Ripke
2014-02-28

Calcium signalling and psychiatric disease: bipolar disorder and schizophrenia
2014-06-01

Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome

Erik Boot, Stephan Eliez, Maria Niarchou, Linda E Campbell, Martin Debbané, Marianne Bernadette van den Bree, Kieran Murphy, Declan Murphy, Raquel E Gur, Abraham Weizman, Donna M McDonald-McGinn, Therese van Amelsvoort, Maude Schneider, Carrie E Bearden, Stephen R. Hooper, Wendy R Kates
2014-02-19

Risk genes for schizophrenia: translational opportunities for drug discovery

Catherine Winchester
2014-02-13

Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity

Klara Spalek, Christian Vogler, David Coynel, Angela Heck, Annette Milnik, Hanna Kaduszkiewicz, Horst Bickel, Michael Pentzek, Siegfried Weyerer, Steffi G. Riedel-Heller, Patrick F. Sullivan, Stephan Ripke, Andreas Papassotiropoulos, Wolfgang Maier, Steffen Wolfsgruber, Frank Jessen, Michael Wagner
2014-02-02

A general framework for estimating the relative pathogenicity of human genetic variants

Martin Kircher, Brian J O'Roak, Gregory M Cooper, Jay Shendure, Daniela Witten
2014-02

PI3K and cancer: lessons, challenges and opportunities
2014-01-22

A polygenic burden of rare disruptive mutations in schizophrenia

Steven A McCarroll, Stacey Gabriel, Eric Lander, Stephen J Haggarty, Sarah E Bergen, Douglas M. Ruderfer, Jennifer L. Moran, Jyoti Choudhary, Patrik K E Magnusson, Christina M. Hultman, Patrick F. Sullivan, Pamela Sklar
2014-01-22

De novo mutations in schizophrenia implicate synaptic networks

George Kirov, Steven A McCarroll, Michael C O'Donovan, Eilis Hannon, Jessica Johnson, Priit Palta, Elliott Rees, Padhraig Gormley, Douglas M. Ruderfer, Jennifer L. Moran, Peter Holmans, Seth G. Grant, Andrew Pocklington, Samuel A Rose, Aarno Palotie, Pamela Sklar, Edward M Scolnick, Shaun M Purcell, Kimberly Chambert, Sarah L Dwyer, Vihra Milanova, Isla Humphreys, Noa Carrera, Panos Roussos
2014-01-17

The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for GxE research

Desmond Campbell, Olesya Ajnakina
2014-01-14

Analysis of schizophrenia-related genes and electrophysiological measures reveals ZNF804A association with amplitude of P300b elicited by novel sounds

Sarah E Bergen, Robert McCarley, Tracey L Petryshen
2014-01-14

Effects of ZNF804A on auditory P300 response in schizophrenia

Daniela Tropea, Michael Gill, Derek W. Morris, John J. Foxe, Aiden Corvin, Gary J. Donohoe
2014-01-02

Transcriptome-wide discovery of microRNA binding sites in human brain

Ryan L. Boudreau
2014-01-01

Revitalizing psychiatric therapeutics
2014-01

Epistasis and quantitative traits: using model organisms to study gene-gene interactions

Trudy Mackay
2014-03-30

Synapse elimination and learning rules co-regulated by MHC class I H2-Db

Jaimie D Adelson, Carla J. Shatz
2014-10-01

Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: a novel transcript fetally regulated by the psychosis risk variant rs1344706.

Brady Maher, Andrew E Jaffe, Daniel R. Weinberger, Helena Cousijn
2014-08-01

Schizophrenia genetics comes of age.
2014-02-01

DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan

William Hennah, Dinesh C. Soares, W. Richard McCombie, Andrew McIntosh, Kathryn L Evans, Nicholas J Brandon, Stephen M Lawrie, Douglas Blackwood, David St Clair
2014-02-01

Is there a flame in the brain in psychosis?

Edward T. Bullmore
2013-12-25

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Andres Metspalu, Tõnu Esko, Harm-Jan Westra, Soumya Raychaudhuri, Jane Worthington, Mark Lathrop, Pilar Galan, Gosia Trynka, Solbritt Rantapää-Dahlqvist, Barbara E. Stranger, Tushar Bhangale, Corinne Miceli-Richard, Luis Rodriguez-Rodriguez, Niek de Vries, Alexandra Zhernakova, Jian Yang, Philippe Dieudé, Matthew A. Brown, Lude Franke, Leonid Padyukov, Sang-Cheol Bae, Javier Martin, Anne Barton, Lars Klareskog, Peter M Visscher, Henk-Jan Guchelaar, Peter K. Gregersen, Hisashi Yamanaka, Paul P Tak, Tom Huizinga, Elizabeth W Karlson, Xavier Mariette, Philip L De Jager, Lindsey A. Criswell, Joshua C. Denny, Michiaki Kubo, Rene E Toes, Robert M Plenge, Eli A Stahl, Marieke J H Coenen, Piet L C M van Riel, Katherine A Siminovitch, Dorothée Diogo, Katherine P Liao, Jeffrey D Greenberg, Joel M Kremer, Ward Ortmann, Towfique Raj, Chikashi Terao, Anne E Eyler, Namrata Gupta, Daniel B Mirel, Mart Afj van de Laar, S Louis Bridges, Hye-Soon Lee, Miguel Angel Gonzalez-Gay, Hyon K Choi, Yoichiro Kamatani, Larry Moreland, Yuta Kochi, Akari Suzuki, Keiko Myouzen, Tsuneyo Mimori, Fumihiko Matsuda, Atsushi Takahashi
2013-12-07

Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex

Huda Akil

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