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Revisiting STAT3 signalling in cancer: new and unexpected biological functions

published in: Nature Reviews Cancer

date of publication: 2014-11-01

language: English

Cites articles 157

Date

Title

Authors

2014-07-21

TLR9 is critical for glioma stem cell maintenance and targeting

Christoph Lahtz, Christine E Brown, Michael Lim, Marcin Kortylewski, Piotr Swiderski
2014-03-13

S1PR1 is crucial for accumulation of regulatory T cells in tumors via STAT3.

Jiehui Deng
2014-01-02

Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal

Charles M. Perou, C. Ryan Miller, David B Darr, Kelly J. Clark
2014-03-27

Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 promotes cell proliferation and migration by upregulating DNMT1 via STAT3 activation
2014-01-14

Toward a new STATe: the role of STATs in mitochondrial function
2014-03-01

Intestinal epithelial cells: regulators of barrier function and immune homeostasis

Lance W Peterson
2013-07-22

Regulation of adipose tissue T cell subsets by Stat3 is crucial for diet-induced obesity and insulin resistance

Joanne E Mortimer, Arthur Riggs
2013-10-31

Loss of androgen receptor expression promotes a stem-like cell phenotype in prostate cancer through STAT3 signaling

Gerhard Müller-Newen
2013-10-29

Leukemia cell-targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity

Anna Kozlowska, Marcin Kortylewski, Qifang Zhang, Piotr Swiderski, Dayson Moreira
2013-01-14

Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition
2013-04-02

G-protein-coupled receptor agonist BV8/prokineticin-2 and STAT3 protein form a feed-forward loop in both normal and malignant myeloid cells

Jiehui Deng, K-U Wagner
2013-08-01

Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically

Oliver Sieber, Joan K. Heath, Florian Greten, Alex Boussioutas, Matthias Ernst, Benjamin T. Kile, Rodney B Luwor
2013-08-01

IL-11: a prominent pro-tumorigenic member of the IL-6 family
2013-07-01

The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis

Elisa de Stanchina, Claudio Ceccarelli, Larry Norton, Mario Taffurelli
2013-05-21

Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer

Samuel Huber, Till Strowig, Eran Elinav, Richard Flavell, Anja Hafemann, Chengcheng Jin, Liming Hao, Stephanie Eisenbarth
2013-11-25

Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance

Chuen Hsueh
2013-06-05

MicroRNA-26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting interleukin-6-Stat3 pathway
2013-05-24

Myeloid clusters are associated with a pro-metastatic environment and poor prognosis in smoking-related early stage non-small cell lung cancer

Karen L. Reckamp
2013-08-02

Metformin therapy and risk of cancer in patients with type 2 diabetes: systematic review

Antonio Nicolucci, Giovanni Strippoli
2013-06-01

Stem cells: bad seeds

Cassandra Willyard
2013-06-10

Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells

Eunhee Kim, Jeremy N Rich
2013-07-03

JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells

Norman Maitland
2013-10-27

Differential regulation of myeloid leukemias by the bone marrow microenvironment

André Catic, Paola Divieti Pajevic, David T Scadden
2013-05-08

Acylglycerol kinase augments JAK2/STAT3 signaling in esophageal squamous cells
2013-04-22

STAT3 acetylation-induced promoter methylation is associated with downregulation of the ARHI tumor-suppressor gene in ovarian cancer
2013-08-05

Histone deacetylase 3 as a novel therapeutic target in multiple myeloma

Balaram Ghosh, Yiguo Hu
2013-09-09

Mitochondrial localized Stat3 promotes breast cancer growth via phosphorylation of serine 727

Vidisha Raje, Paul Dent, Edward J Lesnefsky, Karol Szczepanek, Vasily A Yakovlev, Qifang Zhang
2013

Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice

Panayiotis P. Constantinides
2013-01-03

TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo

Andrew Raubitschek, Marcin Kortylewski, Qifang Zhang, Piotr Swiderski
2012-05-01

S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites

Jiehui Deng, Dave S. Hoon, Andreas Herrmann
2012-10-01

STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation

Brendan J. Jenkins, Chia Huey Ooi
2012-07-30

Let-7 expression is a significant determinant of response to chemotherapy through the regulation of IL-6/STAT3 pathway in esophageal squamous cell carcinoma

Masaki Mori, Yuichiro Doki, Yukinori Kurokawa, Shuji Takiguchi, Kiyokazu Nakajima, Hiroshi Miyata, Rie Hamano, Keijiro Sugimura

Article - wd:Q38262473

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