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The Triggering Receptor Expressed on Myeloid Cells 2 Binds Apolipoprotein E.

pengarang

Michael Farzan

diterbitkan dalam: Journal of Biological Chemistry

tanggal publikasi: 2015-09-15

bahasa: Inggris

Cites articles 39

Date

Judul

Pengarang

2015-04-25

More evidence for association of a rare TREM2 mutation (R47H) with Alzheimer's disease risk

Samantha L Rosenthal, F. Yesim Demirci, M. Ilyas Kamboh
2015-05-08

DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response
2015-04-29

The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease

Wouter van Rheenen, Elisabeth Steinhagen-Thiessen, Frank Faltraco, Christina M Lill, Aleksey Shatunov, Mathias Toft, Andrea Calvo, Ole-Bjørn Tysnes, Robert Perneczky, Adriano Chiò, Vincenzo Silani, Pamela Shaw, Jens Pahnke, Harald Hampel, Stefan J Teipel, Beate Ritz, Ammar Al-Chalabi, Leonard H van den Berg, Gabriella Restagno, Jan H Veldink, SLAGEN Consortium, Ulman Lindenberger, Dan Rujescu, Barbara Castellotti, Hakon Hakonarson, Lars Bertram, Hayrettin Tumani, Cathrin Schnack
2015-04-01

Nuclear receptors license phagocytosis by trem2+ myeloid cells in mouse models of Alzheimer's disease

Tarja Malm, Bruce T Lamb, Richard M Ransohoff
2015-03-02

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models

Paul J Cheng, Daniel R Margevicius, James B Leverenz, Richard M Ransohoff
2015-02-26

TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model

Susan Gilfillan, Marco Colonna, David M. Holtzman
2015-02-01

Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke

Tiina M. Kauppinen, Midori A Yenari
2015-04-20

TREM2 sustains microglial expansion during aging and response to demyelination

Marco Colonna, Susan Gilfillan, Pietro Luigi Poliani
2015-02-24

Disease-Associated Mutations of TREM2 Alter the Processing of N-Linked Oligosaccharides in the Golgi Apparatus.

Hyun Joo An
2014-08-01

More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration

Gary T. Philips
2014-07-22

Upregulation of TREM2 ameliorates neuropathology and rescues spatial cognitive impairment in a transgenic mouse model of Alzheimer's disease

Jin-Tai Yu, Lan Tan, Teng Jiang, Qiao-Quan Zhang
2014-06-04

Coding variants in TREM2 increase risk for Alzheimer's disease

Celeste M Karch, Bruno A Benitez, Carlos Cruchaga, Alison Goate, Sheng Chih Jin, Joanne B Norton, David S Carrell, Oscar Harari, Sarah Bertelsen, Yefei Cai, Breanna Cooper, Tara Skorupa, Simon Hsu
2014-06-03

Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.

Thomas E. Mahan, Laura Piccio, Marco Colonna, David M. Holtzman
2014-04-01

TREM2 variant p.R47H as a risk factor for sporadic amyotrophic lateral sclerosis

Bruno A Benitez, Carlos Cruchaga, Alison Goate, Stanley H Appel, Timothy M Miller, Robert H Baloh, Janet Cady, Craig Zaidman, Peggy Allred, John Ravits, Alan Pestronk
2013-10-16

Heterozygous TREM2 mutations in frontotemporal dementia

Irene Piaceri, Cristian Bonvicini, Massimo Gennarelli, Daniela Galimberti, Benedetta Nacmias, Sandro Sorbi, Elio Scarpini, Barbara Borroni, Chiara Fenoglio, Silvia Bagnoli, Silvana Archetti, Cinzia Barone, Marinella Turla
2013-06-21

TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease

Dennis W. Dickson, Nilüfer Ertekin-Taner, Sruti Rayaprolu, Elizabeth Finger, Charles L White, Maria Barcikowska, Catherine Lomen-Hoerth, Ryan J Uitti, Zbigniew K Wszolek, Rosa Rademakers, Ronald C. Petersen, Bruce L. Miller, Owen A. Ross, William Seeley, David S Knopman, Bradley F Boeve, Grzegorz Opala, Anna Krygowska-Wajs, James F Meschia, Neill R Graff-Radford, Keith A Josephs, Kevin B Boylan, Matt Baker, Carol F Lippa, Eileen H Bigio, Bianca Mullen, Kimmo Hatanpaa, Magdalena Boczarska-Jedynak, Timothy Lynch
2013-01-01

Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement

Jose Bras, Jonathan D Rohrer, Basar Bilgic
2013-01-10

TREM2 variants in Alzheimer's disease

Andrew Singleton, Julie Williams, John Anthony Hardy, Jean-Charles Lambert, Ekaterina Rogaeva, Peter Henry St George-Hyslop, Philippe Amouyel, Carlos Cruchaga, Jose Bras, Kevin Morgan, Alison Goate, Rita Guerreiro, Rosa Rademakers, Tammaryn Lashley, Minerva M Carrasquillo, Elisa Majounie, Celeste Sassi, John Collinge, Steven G. Younkin
2013-01-10

Variant of TREM2 associated with the risk of Alzheimer's disease

Kári Stefánsson, Knut Engedal, Dan Rujescu, Augustine Kong, Hreinn Stefansson, Unnur Þorsteinsdóttir, Cornelia M. van Duijn, Albert Hofman, Ingileif Jonsdottir, M. Arfan Ikram, Ole A. Andreassen, Srdjan Djurovic, Carla Ibrahim-Verbaas, Harald Hampel, Ina Giegling, James J Lah, Stacy Steinberg, Jon Snaedal, Johanna Huttenlocher, Thorlakur Jonsson, Allan Levey, Ingun D. Ulstein
2013-09-27

Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and γ-secretase-dependent intramembranous cleavage

Konstantin Glebov, Harald Neumann, Jochen Walter
2013-10-09

Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia.

Rik Vandenberghe, Sebastiaan Engelborghs, Christine Van Broeckhoven, Julie van der Zee, Peter Paul De Deyn, Marc Cruts, Maria Mattheijssens, Patrick Cras, Tim Van Langenhove, Stéphanie Philtjens, Mathieu Vandenbulcke, Githa Maes, Karolien Bettens, Nathalie Geerts, Elise Cuyvers, Jasper Van Dongen, Kristel Sleegers, Ilse Gijselinck, BELNEU consortium
2011-07-29

Specific lipid recognition is a general feature of CD300 and TREM molecules.
2009-03-19

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

Midori A Yenari
2008-09-01

Mutations in TREM2 lead to pure early-onset dementia without bone cysts.
2007-12-01

TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells

Piia Karisola, Manish J. Butte, Irene Chernova, Gordon J. Freeman, Arlene Sharpe, Masahisa Jinushi
2007-04-01

TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis

Massimiliano Stagi, Harald Neumann, Marco Prinz
2005-02-01

Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2

Harald Neumann
2004-11-01

Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia

Marco Colonna, Roberto Spreafico
2004-11-01

Apolipoprotein E modulates clearance of apoptotic bodies in vitro and in vivo, resulting in a systemic proinflammatory state in apolipoprotein E-deficient mice

Jill Reckless
2003-07-15

Pattern recognition by TREM-2: binding of anionic ligands
2002-09

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

Leena Peltonen-Palotie, Juha Paloneva, Rolf Adolfsson, Yrjö Konttinen
2001-03-01

Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family

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