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The pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia.

author

Christine J Harrison

published in: Leukemia

date of publication: 2015-05-06

main subject: leukemia

Cites articles 115

Date

Title

Authors

2015-03-01

Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia

Markus Müschen, Janetta J Bijl, Natalya Goloviznina, Dirk Baumjohann, Bill H. Chang, Thomas A Milne, Brian Druker, Elisabeth Paietta, Stephen P Hunger
2015-01-29

Signaling mechanisms regulating B-lymphocyte activation and tolerance
2015-01-16

X-linked agammaglobulinemia associated with B-precursor acute lymphoblastic leukemia

Osamu Ohara, Yusuke Okuno, Hirokazu Kanegane
2015-03-01

The pre-BCR to the rescue: therapeutic targeting of pre-B cell ALL.

Iannis Aifantis
2015-01-28

CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk.
2015-02-20

The BAFFling function of Syk in B-cell homeostasis

Friedemann Kiefer
2015-03-23

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

Markus Müschen, Thomas Graeber, Elisabeth Paietta, Stephen P Hunger, Arthur Weiss, Cheryl L. Willman, Mignon L Loh, Seyedmehdi Shojaee, Maike Buchner, Huimin Geng, Ari M Melnick
2015-03-08

CD19: A multifunctional immunological target molecule and its implications for Blineage acute lymphoblastic leukemia

Steffen Koschmieder
2015-01-29

Are patients with X-linked agammaglobulinemia at increased risk of developing acute lymphoblastic leukemia?
2014-06-23

A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia

Christine J Harrison, Anthony V. Moorman, Lucy Chilton
2014-02

Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling

Harinder Singh
2014-03-18

Haematological cancer: idelalisib-targeting PI3Kδ in patients with B-cell malignancies

Klaus Okkenhaug
2014-01-01

SYK as a New Therapeutic Target in B-Cell Precursor Acute Lymphoblastic Leukemia

Fatih M. Uckun
2014-02-14

Interference with pre-B-cell receptor signaling offers a therapeutic option for TCF3-rearranged childhood acute lymphoblastic leukemia
2014-04-07

IGH@ translocations are prevalent in teenagers and young adults with acute lymphoblastic leukemia and are associated with a poor outcome.

Anthony V. Moorman, Christine J Harrison, Anthony H. Goldstone, Adele K Fielding, Lisa Russell, Dino Masic, Amir Enshaei, Ajay Vora
2014-09-01

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

Elaine Mardis, Kelly McCastlain, Andrew S Moore, Richard C Harvey, Sarah K. Tasian, Deborah L. White, Charles G. Mullighan, John Easton, Malcolm A Smith, Guido Marcucci, Ilaria Iacobucci, Marina Konopleva, Ching-Hon Pui, Clara D. Bloomfield, Krzysztof Mrózek, Jessica Kohlschmidt, Elisabeth Paietta, Stephen P Hunger, Nyla A Heerema, Cheryl L. Willman, Julie Gastier-Foster, Meenakshi Devidas, Mignon L Loh, Naomi Winick, Mary V Relling, Debbie Payne-Turner, Deqing Pei, Guangchun Song, Michael Rusch, Kristy Boggs, Shalini C Reshmi, Bhavin Vadodaria, Heather Mulder, Elizabeth A Raetz, Wendy Stock, Steven M Kornblau, Sima Jeha, Daniela S Gerhard, Donald Yergeau, Frank G Keller, Jared B Becksfort, Erin Hedlund, Steven W Paugh, James Whitlock, Shann-Ching Chen, Jinjun Cheng
2014-04-11

Pediatric posttransplant relapsed/refractory B-precursor acute lymphoblastic leukemia shows durable remission by therapy with the T-cell engaging bispecific antibody blinatumomab

Martin Ebinger, Matthias Pfeiffer
2014-09-24

Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition

Christina Halsey, Renate Kirschner-Schwabe, Stefanie Groeneveld-Krentz, Christine J Harrison
2014-09-01

Outcomes of children with BCR-ABL1–like acute lymphoblastic leukemia treated with risk-directed therapy based on the levels of minimal residual disease

Charles G. Mullighan, Ching-Hon Pui, Mary V Relling
2013-08-01

New insights into pre-BCR and BCR signalling with relevance to B cell malignancies
2013-03-01

Targeting pathological B cell receptor signalling in lymphoid malignancies
2013-06-19

Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia

Ian W. Flinn, Nyla A Heerema, Kristie A Blum, Jeffrey A Jones, Jan A Burger, Jeff P Sharman, William G Wierda, Danelle F James, Susan M O'Brien, John C Byrd, Steven Coutre, Weiqiang Zhao, Juthamas Sukbuntherng, Fong Clow
2013-07-24

VPREB1 deletions occur independent of lambda light chain rearrangement in childhood acute lymphoblastic leukemia

Jonathan M Downie, John Kimble Frazer, Richard C Harvey, Charles G. Mullighan, Cheryl L. Willman
2013-07-14

BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint

Markus Müschen, Richard C Harvey, Thomas Graeber, Kazuhiko Igarashi, Cheryl L. Willman
2013-08-28

Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765).
2012-03-20

The clinical relevance of chromosomal and genomic abnormalities in B-cell precursor acute lymphoblastic leukaemia
2012-06-22

Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?

Ching-Hon Pui
2012-12-11

Acute B lymphoblastic leukaemia-propagating cells are present at high frequency in diverse lymphoblast populations

Martin Schrappe, Monique L den Boer, Martin Stanulla
2012-08-12

Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics

Jan Delabie, Martin Rowe, Elaine Jaffe, Elías Campo, Daniel J. Hodson, Erlend B. Smeland, Sam Mbulaiteye, Hans Konrad Müller-Hermelink, Randy D Gascoyne, Wing C Chan, Dennis D Weisenburger, Joseph M Connors, Andreas Rosenwald, Stefania Pittaluga, Wyndham H. Wilson, Thomas Waldmann, Holger Kohlhammer, Arthur L Shaffer, Lisa M Rimsza, Rita M. Braziel, Michele Ceribelli, Xuelu Liu, Philip Kluin, Martin D Ogwang, Alan Bernard Rickinson, Sameer Jhavar
2012-09-21

Homozygous deletions of CDKN2A are present in all dic(9;20)(p13·2;q11·2)-positive B-cell precursor acute lymphoblastic leukaemias and may be important for leukaemic transformation.

Magnus Nordenskjöld, Ann Nordgren
2012-01-22

A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation
2012-10-29

Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia

Thomas A Milne, Markus Müschen, Martin S. Tallman, Elisabeth Paietta, Hillard M. Lazarus, Wei-Yi Chen, Charles David Allis, Selina Luger, Mark R Litzow

Article - wd:Q38460308

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