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Iron neurochemistry in Alzheimer's disease and Parkinson's disease: targets for therapeutics

author

Abdel A. Belaidi

Ashley I. Bush

published in: Journal of Neurochemistry

date of publication: 2015-11-06

language: English

main subject: Alzheimer's disease, Parkinson's disease, neurochemistry

Cites articles 191

Date

Title

Authors

2015-05-19

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Alzheimer's Disease Neuroimaging Initiative, Scott Ayton, Noel G Faux, Ashley I. Bush
2015-01-01

Biometals and their therapeutic implications in Alzheimer's disease

Scott Ayton, Ashley I. Bush
2015-02-01

Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein

Dominic J. Hare, Scott Ayton, Peng Lei, James A. Duce, Catriona A. McLean, Jack T Rogers, David I Finkelstein, Ashley I. Bush
2015-07-22

Decrease in APP and CP mRNA expression supports impairment of iron export in Alzheimer's disease patients

Bruno Silva, Ângela C Crespo, Liliana Marques, Carolina Maruta, Arminda Vilares, Paula Faustino, Ana Verdelho, Madalena Martins
2015-06-02

Intranasal deferoxamine attenuates synapse loss via up-regulating the P38/HIF-1α pathway on the brain of APP/PS1 transgenic mice
2015-06-23

Is early-life iron exposure critical in neurodegeneration?

Dominic J. Hare, Philip A. Doble, David I Finkelstein, Ashley I. Bush
2015-01-23

Decreased plasma iron in Alzheimer's disease is due to transferrin desaturation.

Dominic J. Hare, Philip A. Doble, Ashley I. Bush, James Doecke, Colin L. Masters, Blaine R Roberts, Noel G Faux, Irene Volitakis, Alan Rembach, Rudolf Grimm
2015-03-18

Ferroptosis as a p53-mediated activity during tumour suppression
2015-03-18

Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse

Peng Lei, Scott Ayton, David I Finkelstein, Ashley I. Bush
2015-06-23

Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism

Ruslan Rafikov
2015-05-22

High nigral iron deposition in LRRK2 and Parkin mutation carriers using R2* relaxometry.

Jean-Christophe Corvol, Hartwig R. Siebner, Marie Vidailhet
2014-07-10

Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson's disease

Scott Ayton, Peng Lei, Ashley I. Bush, David I Finkelstein
2014-03-13

Labile iron in cells and body fluids: physiology, pathology, and pharmacology

Zvi Ioav Cabantchik
2014-02-15

Widespread age-related differences in the human brain microstructure revealed by quantitative magnetic resonance imaging

Martina F. Callaghan, Patrick Freund, Antoine Lutti, Gunther Helms, Bogdan Draganski, Nikolaus Weiskopf, Marinella Cappelletti
2014-02-06

Targeting chelatable iron as a therapeutic modality in Parkinson's disease

Jérome Kluza, Philippe Marchetti, David Devos, Jean-Christophe Corvol, Marcel Leist, Luc Defebvre
2014-01-01

The role of iron and reactive oxygen species in cell death
2014-01-14

An anemia of Alzheimer's disease

Noel G Faux, Ashley I. Bush, James S Wiley, Ralph Martins
2014-12

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Frauke Neff, Jose Pedro Friedmann Angeli, Nadja Herbach, Rüdiger Wanke, Marcus Conrad, Vladimir Tyurin, Devaraj Basavarajappa, Valerie O'Donnell, Olof Rådmark, Irene Esposito, Georg W Bornkamm, Yulia Y. Tyurina, Valerian E. Kagan
2014-09-19

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

Dieter Adam, David William Andrews, Klas Blomgren, Jerry E. Chipuk, Klaus-Michael Debatin, Richard Flavell, Simone Fulda, Hinrich Gronemeyer, Hidenori Ichijō, Sharad Kumar, Andreas Linkermann, Carlos López Otín, Jean-Christophe Marine, Cristina Muñoz-Pinedo, Theocharis Panaretakis, Josef M Penninger, Paolo Pinton, Rosario Rizzuto, Erwin F. Wagner, Boris Zhivotovsky, José Manuel Bravo-San Pedro, Ilio Vitale, Mathieu Jm Bertrand, Katiuscia Bianchi, Francesco Cecconi, John A Cidlowski, Vincenzo De Laurenzi, Wafik El-Deiry, Gian Maria Fimia, Douglas R. Green, Michael Otmar Hengartner, Thomas Kaufmann, Walter Malorni, Seamus J. Martin, Jean-Claude Martinou, Pascal Meier, Marcus E. Peter, Jochen Prehn, Hamsa Puthalakath, Kodi Ravichandran, Cecilia Rodrigues, Yufang Shi, Hans-Uwe Simon, Stephen Tait, Nektarios Tavernarakis, Tom Vanden Berghe, Peter Vandenabeele, Eileen White, Oliver Kepp, Mikhail Blagosklonny, Henning Walczak, Aaron Ciechanover, Beth Levine, Lorenzo Galluzzi, Nicola Di Daniele, Mizushima Noboru, Mauro Piacentini, Gerry Melino, Guido Kroemer
2014-09-19

R2* mapping for brain iron: associations with cognition in normal aging.

Eric Jouvent, Franz Fazekas, Martin Dichgans, Hugues Chabriat, Marco Duering, Jean-Francois Mangin
2014-08-27

Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases
2014-08-14

Motor and cognitive deficits in aged tau knockout mice in two background strains

Scott Ayton, David I Finkelstein, Ashley I. Bush
2014-07

sAPP modulates iron efflux from brain microvascular endothelial cells by stabilizing the ferrous iron exporter ferroportin
2014-10-15

A novel model for brain iron uptake: introducing the concept of regulation

Kavi Devraj
2014-10-01

The role of iron in brain ageing and neurodegenerative disorders

Roberta J Ward, Fabio A Zucca
2014-01-01

The molecular biology of human iron metabolism
2014-08-23

A comparison of ceruloplasmin to biological polyanions in promoting the oxidation of Fe(2+) under physiologically relevant conditions

Bruce X. Wong, Ashley I. Bush, James A. Duce, Scott Ayton
2014-12-02

β-Amyloid precursor protein does not possess ferroxidase activity but does stabilize the cell surface ferrous iron exporter ferroportin

Bruce X. Wong, James A. Duce, Ashley I. Bush
2014-06-13

The physiological functions of iron regulatory proteins in iron homeostasis - an update

De-liang Zhang
2014

An iron–dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta

Gawain McColl, Colin L. Masters
2013-12-25

H63D mutation in hemochromatosis alters cholesterol metabolism and induces memory impairment

Patricia S Grigson
2013-02-19

Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease.

James A. Duce, Bruce X. Wong, Ashley I. Bush, David I Finkelstein

Article - wd:Q38627193

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