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p21 promotes sustained liver regeneration and hepatocarcinogenesis in chronic cholestatic liver injury

author

Karl Lenhard Rudolph

1969 -

Sarah-Fee Katz

published in: Gut

date of publication: 2013-10-03

language: English

Cites articles 23

Date

Title

Authors

2013-08-07

The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice

Bruno Guigas, Michael Manns
2012-09-06

Liver failure after extended hepatectomy in mice is mediated by a p21-dependent barrier to liver regeneration.

Rolf Graf, Oliver Tschopp, Kuno Lehmann, Pierre-Alain Clavien, Bostjan Humar
2012-04-26

HSCs play a distinct role in different phases of oval cell-mediated liver regeneration
2012-02-15

Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation.

Daniel Hartmann, Hans A Kestler, Michael R. Speicher, Karl Lenhard Rudolph, Sarah-Fee Katz, Yvonne Begus-Nahrmann, Birgit Liß, Parisa Eshraghi, André Lechel
2012-01-10

Comparison of hepatocellular carcinoma in American and Asian patients by tissue array analysis

Mithat Gönen, Yuman Fong, David S Klimstra, William R Jarnagin, Michael Hezel, Scott Tuorto
2011-06-01

Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice

Markus Grompe
2011-11-21

Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration

Bruce Wang, Dirk Grimm
2010-01-25

Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks

Eithan Galun
2010-03-01

Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation

Markus Peck-Radosavljevic, Michael Karin, Vladislav Temkin
2010-02-26

Signal transducer and activator of transcription 3 protects from liver injury and fibrosis in a mouse model of sclerosing cholangitis

Gernot Zollner, Monica Musteanu, Peter Fickert, Martin Bilban, Lukas Kenner, Valeria Poli, Leander Blaas, Jan-Wilhelm Kornfeld, Emilio Casanova, Wolfgang Mikulits, Robert Eferl, Michael Trauner, Judith Gumhold, Doris Schneller, Harald Esterbauer, Andrea Fuchsbichler
2009-06-12

Enrichment and clonal culture of progenitor cells during mouse postnatal liver development in mice.

Akihide Kamiya
2008-07-01

Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis

Zhongya Wang, Markus Grompe
2008-11-06

Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

Erwin F. Wagner, Kurt Zatloukal
2007-11-14

Somatic cell type specific gene transfer reveals a tumor-promoting function for p21(Waf1/Cip1)

Eric C Holland
2007-04-01

Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis

Massimo Roncalli, Karl Lenhard Rudolph, Young Nyun Park
2006-02-06

Tumorigenic activity of p21Waf1/Cip1 in thymic lymphoma.

Manuel Serrano
2006-04-01

Multiple adaptive mechanisms to chronic liver disease revealed at early stages of liver carcinogenesis in the Mdr2-knockout mice.

Eithan Galun, Jasmine Jacob-Hirsch, Mark Katzenellenbogen, Ninette Amariglio, Gidi Rechavi, Eytan Domany, Orit Pappo, Naama Klopstock, Lina Mizrahi, Devorah Olam, Daniel S Goldenberg
2005-07-01

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis.

Michael Karin
2004-07-01

Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.

Gernot Zollner, Kurt Zatloukal, Michael Trauner, Arthur Kaser, Helmut Denk
2002-04-01

High expression of p21WAF1/CIP1 is correlated with human hepatocellular carcinoma in patients with hepatitis C virus-associated chronic liver diseases
2001-09-01

A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liver

George C Yeoh
1996-03-01

Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I

Markus Grompe
1993-11-05

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

Article - wd:Q39087205

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