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Dysregulation of Brain Stress Systems Mediates Compulsive Alcohol Drinking

author

Brendan Tunstall

George Koob

1947 -

published in: Current Opinion in Behavioral Sciences

date of publication: 2016-11-19

Cites articles 47

Date

Title

Authors

2017-02-01

Differences Between Treatment-Seeking and Nontreatment-Seeking Alcohol-Dependent Research Participants: An Exploratory Analysis
2016-04-25

The CRF1 Antagonist Verucerfont in Anxious Alcohol-Dependent Women: Translation of Neuroendocrine, But not of Anti-Craving Effects

Reza Momenan
2016-03-10

An Animal Model of Alcohol Dependence to Screen Medications for Treating Alcoholism
2016-03-15

11β-hydroxysteroid dehydrogenase inhibition as a new potential therapeutic target for alcohol abuse
2016-02-01

Does Acamprosate Really Produce its Anti-Relapse Effects via Calcium? No Support from the PREDICT Study in Human Alcoholics
2015-10-22

Existing and Future Drugs for the Treatment of the Dark Side of Addiction

George Koob
2015-09-16

Endocannabinoid signalling in reward and addiction.

Yasmin Hurd
2015-06-26

Roles for the endocannabinoid system in ethanol-motivated behavior

Daniel Morgan
2015-06-29

Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals

Marian L. Logrip, M Adrienne McGinn, Olivier George, George Koob, Leandro F Vendruscolo, Joel E Schlosburg
2015-06-24

Dissociating Motivational From Physiological Withdrawal in Alcohol Dependence: Role of Central Amygdala κ-Opioid Receptors
2015-06-02

Role of the α1 blocker doxazosin in alcoholism: a proof-of-concept randomized controlled trial
2015-04-30

Divergent regulation of distinct glucocorticoid systems in alcohol dependence
2015-02-02

Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks

Andrea Califano, George Koob
2015-03-13

The corticotropin releasing hormone-1 (CRH1) receptor antagonist pexacerfont in alcohol dependence: a randomized controlled experimental medicine study

Marilyn Huestis, Markus Heilig
2014-05-01

Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis
2014-01-01

Gabapentin treatment for alcohol dependence: a randomized clinical trial
2014-03

Acamprosate produces its anti-relapse effects via calcium
2014-08-20

Memantine reduces alcohol drinking but not relapse in alcohol-dependent rats

Jerome Jeanblanc, Mickael Naassila
2013-11-01

Operant alcohol self-administration in dependent rats: focus on the vapor model
2012

Stress and the HPA axis: role of glucocorticoids in alcohol dependence
2012-05-01

Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats

Marian L. Logrip, George Koob, Leandro F Vendruscolo, Joel E Schlosburg, Eric Zorrilla
2011-02-11

Evidence that vasopressin V1b receptors mediate the transition to excessive drinking in ethanol-dependent rats

George Koob
2011-01-01

Systemic κ-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats

George Koob
2011-02-19

κ-opioid receptors are implicated in the increased potency of intra-accumbens nalmefene in ethanol-dependent rats

Alexander C W Smith
2010-07-31

Effects of β-adrenoceptor antagonists on alcohol drinking by alcohol-dependent rats

Nicholas W Gilpin, George Koob
2009-05

The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking

Valentina Sabino, Pietro Cottone, Bruno Conti, Luca Steardo, George Koob
2008-05-01

Cellular and behavioral interactions of gabapentin with alcohol dependence

George Koob
2008-03-01

alpha1-noradrenergic receptor antagonism blocks dependence-induced increases in responding for ethanol

George Koob
2008-02-14

Neurokinin 1 receptor antagonism as a possible therapy for alcoholism

Annika Thorsell
2008-02

Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence

George Koob
2007-09-01

Acamprosate in alcohol dependence: implications of a unique mechanism of action
2007-04-10

A CRF(2) agonist administered into the central nucleus of the amygdala decreases ethanol self-administration in ethanol-dependent rats

George Koob

Article - wd:Q39365977

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