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Preventing Alzheimer's disease

author

Dennis J. Selkoe

1943 -

published in: Science

date of publication: 2012-09-01

language: English

main subject: Alzheimer's disease

Cites articles 32

Date

Title

Authors

2012-02-03

Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis

Nick C. Fox, David J. Brooks, Reisa Sperling, Lawrence S Honig, Jerome Barakos, Enchi Liu, Michael Grundman, Stephen Salloway
2012-08-01

Reversal of paralysis and reduced inflammation from peripheral administration of β-amyloid in TH1 and TH17 versions of experimental autoimmune encephalomyelitis

Leonard Herzenberg, Leonore Herzenberg
2012-03-04

Cognitive activity, education and socioeconomic status as preventive factors for mild cognitive impairment and Alzheimer's disease
2011-01-01

National estimates of the prevalence of Alzheimer's disease in the United States

Kenneth M Langa, Walter A. Kukull, Steven G. Heeringa, Ron Brookmeyer
2011-04-01

Alzheimer's disease: the challenge of the second century

Alison Goate, David M. Holtzman, John C. Morris
2011-12-01

Recommendations for the incorporation of biomarkers into Alzheimer clinical trials: an overview.

Dennis J. Selkoe, John C. Morris
2011-05

Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

Laurel A. Beckett, Clifford Jack, Jeffrey Kaye, Yaakov Stern, David A Bennett, Maria C Carrillo, Anne M Fagan, Eric M. Reiman, Kristine Yaffe, Paul S. Aisen, Reisa Sperling, Eric R Siemers, Suzanne Craft, Marcelle Morrison-Bogorad, Creighton H Phelps, Thomas J Montine
2011-10-10

Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab.

David J. Brooks, William E. Klunk, Frederik Barkhof
2011-01-01

Anti-aβ therapeutics in Alzheimer's disease: the need for a paradigm shift
2011-11-30

Testing the right target and right drug at the right stage
2011-01-06

Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease

Randall J. Bateman, Nick C. Fox, Paul S. Aisen, Bart De Strooper
2011-03-18

Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

Dennis J. Selkoe
2011-06-01

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

Joseph M Castellano, Jungsu Kim, Randall J. Bateman, Carlos Cruchaga, Alison Goate, David M. Holtzman, John C. Morris, Anne M Fagan, Bruce W Patterson, Kwasi G. Mawuenyega, Kelly R Bales, Ronald B DeMattos
2011-09-07

Resolving controversies on the path to Alzheimer's therapeutics

Dennis J. Selkoe
2010-01

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

David S Knopman, Ronald C. Petersen, John Q. Trojanowski, Paul S. Aisen
2010-02-01

The secretases: enzymes with therapeutic potential in Alzheimer disease

Bart De Strooper
2010-02-26

11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

William E. Klunk, Nick C. Fox, David J. Brooks, Kaj Blennow, Martin Rossor, Juha O. Rinne, Aren A Okello, Jerome Barakos, Enchi Liu, Michael Grundman
2009-04-01

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

Alzheimer's Disease Neuroimaging Initiative, Malgorzata Knapik-Czajka, Kaj Blennow, John Q. Trojanowski, Ronald C. Petersen, Paul S. Aisen, Leslie M. Shaw, Hugo Vanderstichele, Holly D Soares, Eric R Siemers, Piotr Lewczuk
2009-02-01

Decreased cerebrospinal fluid Abeta(42) correlates with brain atrophy in cognitively normal elderly

David M. Holtzman, John C. Morris, Anne M Fagan, Daniel S. Marcus, Mark A. Mintun
2009-06-01

Alzheimer disease: multiple causes, multiple effects of apolipoprotein E4, and multiple therapeutic approaches.
2008-09-01

Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial

Kathryn R. Greenop, Osvaldo P. Almeida, Leon Flicker, Nicola T Lautenschlager, Kay L Cox, Frank M van Bockxmeer
2007-01-08

Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults

Mark A. Mintun, David M. Holtzman, John C. Morris, Anne M Fagan, Catherine M Roe
2007-02

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

Christian Haass, Dennis J. Selkoe
2007-06

A beta oligomers - a decade of discovery
2007-05-01

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

Erik D. Roberson, Lennart Mucke
2006-06-27

Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease.

Susanne Wolf, Golo Kronenberg, Rupert Overall, Gerd Kempermann, Matthias Staufenbiel
2006-05-26

Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms

Adam D Bachstetter
2006-02-08

Leisure activities and the risk of amnestic mild cognitive impairment in the elderly

Richard B. Lipton, J. Verghese
2004-01-21

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

William E. Klunk, Bengt Långström, Agneta Nordberg, Sergio Cerdeira
2002-06-01

Late-life engagement in social and leisure activities is associated with a decreased risk of dementia: a longitudinal study from the Kungsholmen project.

Hui-Xin Wang, Bengt Winblad
1995-10-01

Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease.
1993-08-13

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Jonathan L Haines

Article - wd:Q39549596

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