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Mutations driving CLL and their evolution in progression and relapse

author

Stacey Gabriel

Eric Lander

1957 -

Stephan Stilgenbauer

Johannes G Reiter

Mara Rosenberg

Daniel Mertens

Ivana Bozic

Hartmut Döhner

1957 -

Michael Hallek

1959 -

Gad Getz

Dan A Landau

Μάρτιν Νόβακ

1965 -

Jasmin Bahlo

Chip Stewart

Donna Neuberg

δημοσιεύθηκε στο: Nature

date of publication: 2015-10-14

language: Αγγλικά

Cites articles 40

Date

Title

Authors

2015-05

Chronic lymphocytic leukemia: 2015 Update on diagnosis, risk stratification, and treatment

Michael Hallek
2015-02-20

Low frequency mutations independently predict poor treatment-free survival in early stage chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis

Matthew J Rose-Zerilli, Nicholas Cross
2014-12-11

Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia

Raúl Rabadán, Hossein Khiabanian, Laura Pasqualucci, Robin Foà, Gianluca Gaidano, Giulia Fabbri, Valter Gattei, Roberto Marasca, Jiguang Wang, Giovanni Del Poeta
2014-10-23

Integrated genomic characterization of papillary thyroid carcinoma
2014-09-05

Critical role of SHP2 (PTPN11) signaling in germinal center-derived lymphoma
2014-06-11

Acquired initiating mutations in early hematopoietic cells of CLL patients

Kenichi Yoshida, Satoru Miyano, Daniel Gautheret, Hélène Merle-Béral, Eric Solary, William Vainchenker, Thomas Mercher, Nathalie Droin, Florence Nguyen-Khac, Olivier Bernard, Veronique Della-Valle, M'boyba Diop, Philippe Dessen, Seishi Ogawa, Laurianne Scourzic, Yuichi Shiraishi, Elena Mylonas
2014-02

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

Amaro Taylor-Weiner, Gad Getz, Nick Shillingford, Priscilla K Brastianos, Maria Martinez-Lage, Mark W. Kieran, Adam C Resnick, William C Hahn, Sandro Santagata, Dora Dias-Santagata, Chip Stewart, Edward R. Laws
2014-01-23

Discovery and saturation analysis of cancer genes across 21 tumour types

Eric Lander, Gad Getz, Petar Stojanov, Matthew Meyerson, Craig H Mermel, Stacey Gabriel, Levi A Garraway, Todd Golub
2014-03-20

Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.

Konstanze Döhner, Hartmut Döhner, Thorsten Zenz, Michael Hallek, Peter Lichter, Stephan Stilgenbauer
2013-09-12

Clinical and biological implications of driver mutations in myelodysplastic syndromes

Elli Papaemmanuil, Eva Hellström-Lindberg, Carlo Gambacorti-Passerini, Sarah O'Meara, Moritz Gerstung, Andrea Pellagatti, David C. Wedge, Peter Van Loo, Jacqueline Boultwood, Paresh Vyas, Anthony R Green, Keiran Raine, Jon Teague, Michael Stratton, Calli Latimer, Luca Malcovati, Lynn Quek
2013-08-22

Signatures of mutational processes in human cancer

Jessica Zucman-Rossi, Stian Knappskog, Anne-Lise Børresen-Dale, Marcin Imielinski, Keiran Raine, Carlos Caldas, Elli Papaemmanuil, Jon Teague, Anne Vincent-Salomon, Michael Stratton, P. Andrew Futreal, Sunil R Lakhani, Matthew Meyerson, Barbara Hutter, Marcel Kool, Stefan M. Pfister, Paul A Northcott, Serena Nik-Zainal, David T. W. Jones, Peter F. Stadler, Ralf Küppers, David Langenberger, Helen Davies, Xose S. Puente, Rafael Valdés-Mas
2013-07-11

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Eric Lander, Carrie Sougnez, Gad Getz, Kristian Cibulskis, Wendy Winckler, Daniel Auclair, Lauren Ambrogio, Gordon Saksena, Eran Hodis, Nicolas Stransky, Douglas Voet, Kristin Ardlie, Elizabeth Nickerson, Marcin Imielinski, Aaron McKenna, Melissa Parkin, Adam Kiezun, Petar Stojanov, Yotam Drier, Alfredo Hidalgo-Miranda, Trevor J Pugh, Matthew Meyerson, Jaume Mora, Dmitry A. Gordenin, Kimberly Stegmaier, Craig H Mermel, Stacey Gabriel, Levi A Garraway, Todd Golub, Andrey Sivachenko, Charles W Roberts, Jens G. Lohr, Chip Stewart, Alex H Ramos
2013-05-29

Chronic lymphocytic leukemia: molecular heterogeneity revealed by high-throughput genomics

Dan A Landau
2013-03-29

Cancer genome landscapes

Bert Vogelstein, Kenneth W Kinzler, Βίκτωρ Βελκουλέσκου, Luis Alberto Diaz Jr, Nickolas Papadopoulos, Shibin Zhou
2013-02-01

Evolution and impact of subclonal mutations in chronic lymphocytic leukemia

Carrie Sougnez, Kristian Cibulskis, Gad Getz, Gordon Saksena, Stacey Gabriel, Eric Lander, Nir Hacohen, Alexander R. Vartanov, Matthew Meyerson, Andrey Sivachenko, Dan A Landau, Aaron McKenna, Chip Stewart, Donna Neuberg
2013-02-21

Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

Gianluca Gaidano, Laura Pasqualucci, Riccardo Dalla-Favera, Silvia Rasi, Francesco Forconi, Valeria Spina, Valter Gattei, Hossein Khiabanian, Roberto Marasca, Raúl Rabadán, Giovanni Del Poeta, Josep Nomdedeu, Francesco Bertoni, Robin Foà, Michele Dal Bo, Gianluca Gaidano, Francesca Maria Rossi, Pietro Bulian, Alessio Bruscaggin, Carmela Ciardullo, Clara Deambrogi
2013-10-31

Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome

Teresa Davoli
2013-02-24

The evolutionary biography of chronic lymphocytic leukemia

Carlos López Otín, Xose S. Puente
2013-01-09

Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation

Anna Terry, Mikhail Spivakov, Matthias Merkenschlager, Benjamin Taylor, Amanda Fisher, Enrico Petretto
2012-08-27

Far upstream element binding protein 1: a commander of transcription, translation and beyond
2012-08-22

Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns
2012-05-01

Absolute quantification of somatic DNA alterations in human cancer

Kristian Cibulskis, Gad Getz, Wendy Winckler, Eric Lander, Matthew Meyerson, Barbara A Weir, Rameen Beroukhim, Aaron McKenna
2012-11-20

BRAF mutations in chronic lymphocytic leukemia

Stephan Stilgenbauer, Hartmut Döhner, Thorsten Zenz
2012-11-12

MGA, a suppressor of MYC, is recurrently inactivated in high risk chronic lymphocytic leukemia.

Rossana Maffei, Maurizio Martini, Francesco Forconi, Roberto Marasca, Luigi Maria Larocca, Francesco Bertoni, Lorenzo De Paoli, Marco Ladetto, Gianluca Gaidano, Alessio Bruscaggin, Rosella Famà, Michaela Cerri, Valeria Spina
2012-10-09

High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations

Daniel Mertens, Jan Korbel, Stanley Pounds
2011-12-11

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

Xavier Estivill i Pallejà, Víctor Quesada, Pedro Jares, Laia Bassaganyas, Sílvia Beà, Dolors Colomer, Alba Navarro, María Rozman, Julio Delgado, Jesus Maria Hernandez Rivas, Marcos González Díaz, Gloria Velasco, Jose M Freije, Romina Royo, Josep Lluís Gelpí, David G. Pisano, Miguel Vazquez, Heinz Himmelbauer, Elías Campo, Carlos López Otín, Marta Aymerich, Modesto Orozco, Xose S. Puente, Tycho Baumann, Eva Giné, Armando López-Guillermo, Gonzalo Ordonez, Diana Puente, Laura Conde de la Rosa, Neus Villamor, Magda Pinyol, Alejandra Martínez-Trillos, Mónica López-Guerra
2011-06-16

BRAF mutations in hairy-cell leukemia

Laura Pasqualucci, Francesco Forconi, Giorgio Inghirami, Gianluca Schiavoni, Paolo Sportoletti, Luca Arcaini, Raúl Rabadán, Francesco Di Raimondo, Livio Trentin, Brunangelo Falini, Pellegrino Musto, Gianpietro Semenzato, Torsten Haferlach, Claudia Haferlach, Susanne Schnittger, Robin Foà, Stefano A Pileri, Enrico Tiacci, Maria Paola Martelli, Arcangelo Liso, Laurent Farinelli, Valentina Pettirossi
2011-06-05

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

Cristian Tornador, Manel Juan, Keiran Raine, Alfonso Valencia, Michael Stratton, P. Andrew Futreal
2010-10-01

Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial
2010-09-27

Accumulation of driver and passenger mutations during tumor progression

Bert Vogelstein, Ivana Bozic, Kenneth W Kinzler, Μάρτιν Νόβακ, Tibor Antal, Rachel Karchin
2010-08-09

Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells

Yohan Oh
2010-06-15

RG7204 (PLX4032), a selective BRAFV600E inhibitor, displays potent antitumor activity in preclinical melanoma models

Gideon Bollag

Article - wd:Q39714436

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