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NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink

author

Benjamin Cravatt

1970 -

published in: Nature Chemical Biology

date of publication: 2013-03-03

Cites articles 56

Date

Title

Authors

2012-11-01

Influence of threonine metabolism on S-adenosylmethionine and histone methylation

Lewis C. Cantley, George Q. Daley, Ng Shyh-Chang, Hao Zhu, Jason W. Locasale
2012-09-10

Epigenetic regulation of cell adhesion and communication by enhancer of zeste homolog 2 in human endothelial cells
2012-08-31

IKK-ε coordinates invasion and metastasis of ovarian cancer

Anne M Noonan
2012-07-01

Cancer epigenetics: from mechanism to therapy

Mark A. Dawson, Tony Kouzarides
2012-03-07

A two-way street: reciprocal regulation of metabolism and signalling

Kathryn E Wellen, Craig B. Thompson
2012-02-15

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

Carl Campos
2012-03-16

Current chemical biology approaches to interrogate protein methyltransferases
2011-12

N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

Tomas Lindahl, Chengqi Yi
2011-09-13

Structural Basis of Substrate Recognition in Human Nicotinamide N -Methyltransferase
2011-07-01

Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer

Benjamin Cravatt
2011-08-18

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

Mari Mino-Kenudson, Nada Y Kalaany, Walter W Chen, Richard Possemato, Jordi Barretina Ginesta, Levi A Garraway, David E Root, Glenn S Cowley, David M. Sabatini, Kıvanç Birsoy
2011-03

Hallmarks of Cancer: The Next Generation

Douglas Hanahan, Robert Weinberg
2011-01-01

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

Qun-Ying Lei
2011-03-16

Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation

En-Pei Isabel Chiang
2010-11-02

Nicotinamide N-methyltransferase induces cellular invasion through activating matrix metalloproteinase-2 expression in clear cell renal cell carcinoma cells
2010-11-15

Characterization of nicotinamidases: steady state kinetic parameters, classwide inhibition by nicotinaldehydes, and catalytic mechanism

Jarrod French, Yana Cen
2010-10-15

Histone lysine methylation and demethylation pathways in cancer
2010-08-12

Activity-based protein profiling for biochemical pathway discovery in cancer

Benjamin Cravatt
2010-07-01

Fatty liver and fibrosis in glycine N-methyltransferase knockout mice is prevented by nicotinamide

Manel Esteller, David Fernández-Ramos, Josep Julve, José M Mato
2010-06-17

SNAI2/Slug promotes growth and invasion in human gliomas
2010-01-01

Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis

Benjamin Cravatt
2009-12-01

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Robert M. Prins, Patrick S. Ward, Linda Liau, Lewis C. Cantley
2009-06-09

DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation

Gangning Liang
2009-04-02

A molecular signature for Epithelial to Mesenchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis

Claudio Isella
2009-04-01

PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma

Jukka Westermarck, Kirsi Ketola, Melissa Hector-Greene, Anna Sablina, William C Hahn
2009-02-16

Expression of nicotinamide N-methyltransferase in hepatocellular carcinoma is associated with poor prognosis

Jae-Won Joh
2009-02-26

Serum levels of nicotinamide N-methyltransferase in patients with lung cancer.
2009-08

A combined experimental and theoretical study of the pH-dependent binding mode of NAD+by water-soluble molecular clips
2008-09-05

Cancer cell metabolism: Warburg and beyond

David M. Sabatini
2008-08-25

Overlapping gene expression profiles of cell migration and tumor invasion in human bladder cancer identify metallothionein 1E and nicotinamide N-methyltransferase as novel regulators of cell migration
2008-06-03

Protein phosphatase 2A regulatory subunits and cancer

Pieter J Eichhorn, René Bernards
2008-02

Brick by brick: metabolism and tumor cell growth

Ralph J DeBerardinis

Article - wd:Q39968449

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