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Dietary polyunsaturated fatty acids and the Pro12Ala polymorphisms of PPARG regulate serum lipids through divergent pathways: a randomized crossover clinical trial

yazar

Johanna Kuusisto

1959 -

Jyrki Ågren

2000 -

Jussi Pihlajamäki

2000 -

Marjukka Kolehmainen

1968 -

Jussi Paananen

Dorota Kaminska

Markku Laakso

1949 -

yayınlandığı: Genes & Nutrition

yayımlanma tarihi: 2015-10-07

main subject: Yağ asidi

Cites articles 33

Date

Başlık

Yazarlar

2012-12-23

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion

Gonçalo Abecasis, Johanna Kuusisto, Alena Stančáková, Francis Collins, Christian Fuchsberger, Karen L Mohlke, Markku Laakso, Michael Boehnke, Anne U Jackson, Heather M Stringham, Mark Joseph Daly, Tanya M Teslovich, Benjamin M. Neale, Roxann Ingersoll, Peter S Chines, Martin L Buchkovich, Jeroen R Huyghe, Richard M Watanabe, Henna Cederberg, Laura Scott, Marie P Fogarty, Xueling Sim
2012

Beyond the fourth wave of genome-wide obesity association studies
2012-09

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Alena Stančáková, Johanna Kuusisto, Eric Boerwinkle, Eleftheria Zeggini, Unnur Þorsteinsdóttir, Stavroula Kanoni, Claudia Langenberg, Valgerdur Steinthorsdottir, Martina Müller-Nurasyid, Andres Metspalu, Tõnu Esko, Panos Deloukas, Samuli Ripatti, Ann-Christine Syvänen, Tiinamaija Tuomi, Valeriya Lyssenko, Bo Isomaa, Soumya Raychaudhuri, Jouko Saramies, George Dedoussis, Josée Dupuis, André Uitterlinden, Ulf de Faire, Harald Grallert, Jaakko Tuomilehto, Rafn Benediktsson, Veikko Salomaa, Bengt Sennblad, Candace Guiducci, Markku Laakso, Karl-Heinz Jöckel, Sonali Pechlivanis, Raimund Erbel, Inga Prokopenko, Kathleen Stirrups, Inger Njølstad, Stéphane Lobbens, Sailaja Vedantam, Valur Emilsson, Leena Kinnunen, Satu Männistö, Leena Peltonen-Palotie, Cordelia Langford, Thomas Illig, David Altshuler, Barbara Thorand, Christian Gieger, Philippe Froguel, Beverley Balkau, Christian Dina, Danish Saleheen, Anders Hamsten, Albert Hofman, Erik Ingelsson, Gudmar Thorleifsson, Kári Stefánsson, Augustine Kong, Wolfgang Rathmann, Rainer Rauramaa, Christian Herder, Denis Rybin, Eric Sijbrands, Olle Melander, Rob M. van Dam, Gonçalo Abecasis, Cecilia Lindgren, Alan R. Shuldiner, James S. Pankow, Wendy Winckler, Melissa Parkin, Bruna Gigante, Kristian Hveem, Francis Collins, Damiano Baldassarre, Karl Gertow, Pierre Fontanillas, Karin Leander, Han Chen, Ross M. Fraser, Ashish Kumar, Loic Yengo, Sarah E. Hunt, Rona J Strawbridge, Andrew Tym Hattersley, Nita G. Forouhi, Timo A. Lakka, Markus M Nöthen, Johan G. Eriksson, Eeva Korpi-Hyövälti, Sirkka Keinänen-Kiukaanniemi, Kaarel Krjutškov, Eero Lindholm, Anna E Jonsson, Anubha Mahajan, Stephen E Humphries, Julia Meyer, John Beilby, Karen L Mohlke, Inês Barroso, Krista Fischer, Man Li, Peter Donnelly, Mark McCarthy, Kay-Tee Khaw, Nicholas J. Wareham, Michael Boehnke, Anne U Jackson, Ruth J. Loos, Cornelia M. van Duijn, Sekar Kathiresan, Heather M Stringham, Lori L Bonnycastle, Lars Lind, James B. Meigs, David J. Hunter, Lu Qi, Annette Peters, Jian'an Luan, Delilah Zabaneh, Benjamin F. Voight, Norman Klopp, Tim Frayling, Peter Almgren, Tanya M Teslovich, Richard N. Bergman, Tom Wilsgaard, James F. Wilson, Frank Hu, Michael Roden, John Danesh, Caroline S Fox, Nancy Pedersen, Alexander S Doney, Colin Palmer, Simon C Potter, Peter S Chines, Elizabeth J Rossin, Antigone S. Dimas, Marilyn C Cornelis, Oddgeir L Holmen, Andrew R Wood, Mieke D Trip, G Kees Hovingh, Jackie F Price, Laura Scott, Leif Groop, Ayellet V Segrè, Hyun Min Kang, Vasiliki Lagou, Wen Hong Linda Kao, Emil Rehnberg, Suthesh Sivapalaratnam, Mustafa Atalay, Guillaume Charpentier, Mozhgan Dorkhan, Elodie Eury, Tom Forsen, Astradur B Hreidarsson, Jennie Hui, Jasmina Kravic, Ghazala K. Mirza, Thomas W Mühleisen, Arthur William Bill Musk, Loukianos S Rallidis, Angela Silveira, Gerald Steinbach, Joseph Trakalo, Fabrizio Veglia, Roman Wennauer, Timo E Saaristo, Juha Saltevo, Stephane Cauchi, Harry Campbell, Emmi Tikkanen, Bernhard Otto Boehm, Sonia Shah, Peter Kraft, Andrew D Morris, Andrew P Morris, Teresa Ferreira
2012-05-02

Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men

Johanna Kuusisto, Mika Ala-Korpela, Francis Collins, Jussi Pihlajamäki, Jussi Paananen, Mete Civelek, Aldons Jake Lusis, Markku Laakso, Antti J Kangas, Michael Boehnke, Lori L Bonnycastle, Päivi Pajukanta, Alena Stančáková, Mario A. Morken, Henna Cederberg, Niyas K Saleem, Pasi Soininen
2012-04-23

Gene-environment interactions in the development of type 2 diabetes: recent progress and continuing challenges

Frank Hu
2011-11-21

PPARγ Pro12Ala interacts with fat intake for obesity and weight loss in a behavioural treatment based on the Mediterranean diet

José María Ordovás, Marta Garaulet
2011-09-23

Interaction of PPARG Pro12Ala with dietary fat influences plasma lipids in subjects at cardiometabolic risk

Julie A Lovegrove, Susan Jebb, Gary S Frost, Aseel Alsaleh, RISCK Study investigators
2011-04-11

Effects of peroxisome proliferator-activated receptors, dietary fat intakes and gene-diet interactions on peak particle diameters of low-density lipoproteins

Benoît Lamarche, Louis Pérusse, Marie-Claude Vohl, Annie Bouchard-Mercier
2011-11-01

Effect of interaction between PPARG, PPARA and ADIPOQ gene variants and dietary fatty acids on plasma lipid profile and adiponectin concentration in a large intervention study

Tom A. Sanders
2010-12-08

Effects of peroxisome proliferator activated receptor-gamma 2 gene Pro12Ala polymorphism on fasting blood lipids: a meta-analysis.
2009-10-08

Finding the missing heritability of complex diseases

Elaine Mardis, Montgomery Slatkin, Francis Collins, Michael Boehnke, Augustine Kong, Evan E. Eichler, Steven A McCarroll, Peter M. Visscher, Charles Rotimi, Mark McCarthy, Nancy J Cox, Jonathan L Haines, David J. Hunter, Teri Manolio, Lucia A Hindorff, Alice S. Whittemore, Trudy Mackay, Judy H. Cho, Andrew G. Clark, David B. Goldstein
2009-02-17

Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men

Johanna Kuusisto, Markku Laakso, Steven M. Haffner, Alena Stančáková, Teemu Kuulasmaa
2009-01-01

The Pro12Ala PPARgamma2 variant determines metabolism at the gene-environment interface.

Nassim Dali-youcef, Johan Auwerx, Marie-France Champy, Markku Laakso, Eric E Schadt
2005-06-01

Gene-diet interaction in relation to the prevention of obesity and type 2 diabetes: evidence from the Finnish Diabetes Prevention Study

Matti Uusitupa
2005-06-01

The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform

Tuulikki Seppänen-Laakso, William H. Colledge, Mikko Kettunen, Jaswinder K. Sethi, Matej Orešič, Antonio Vidal-Puig, Stephen O'Rahilly, Saverio Cinti, Kevin Brindle, Christopher J. Lelliott, Constantinos Christodoulides, Gema Medina-Gómez, Sam Virtue, Romina Boiani
2005-12-17

The in vivo effects of the Pro12Ala PPARgamma2 polymorphism on adipose tissue NEFA metabolism: the first use of the Oxford Biobank.

Fredrik Karpe
2004-02-01

The Pro12Ala polymorphism of the PPAR gamma 2 gene regulates weight from birth to adulthood.

Jussi Pihlajamäki, Markku Laakso, Mauno Vanhala
2003-04-01

Effect of the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor (PPAR) gamma2 gene on the expression of PPARgamma target genes in adipose tissue of massively obese subjects

Hubert Vidal, Markku Laakso
2003-02-01

The PPAR-gamma P12A polymorphism modulates the relationship between dietary fat intake and components of the metabolic syndrome: results from the Québec Family Study

Julie Robitaille, Louis Pérusse, Marie-Claude Vohl
2002-10-01

Effect of alpha-linolenic acid-rich Camelina sativa oil on serum fatty acid composition and serum lipids in hypercholesterolemic subjects
2002-02-07

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin,Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin

Elizabeth Barrett-Connor, John M. Lachin, William C. Knowler, Richard F. Hamman
2002-08-01

Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study

Virpi Lindi, Jaana Lindström, Sirkka Keinänen-Kiukaanniemi, Jaakko Tuomilehto, Markku Laakso, Pirjo Ilanne-Parikka, Johan G. Eriksson, Timo T. Valle, Helena Hämäläinen, Anne Louheranta, Finnish Diabetes Prevention Study
2001-05-03

Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

Jaana Lindström, Markku Laakso, Jaakko Tuomilehto, Per Eriksson, Sirkka Keinänen-Kiukaanniemi
2001-03-01

Evidence for gene-nutrient interaction at the PPARgamma locus.

Nicholas J. Wareham
2000-09

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

Eric Lander, Tiinamaija Tuomi, Leif Groop, Mark Joseph Daly, David Altshuler, Mia M. Gaudet, Thomas J. Hudson
1999-03

Molecular recognition of fatty acids by peroxisome proliferator-activated receptors
1999-09-01

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

Masafumi Matsuda, Ralph A. DeFronzo
1999-07-01

Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-gamma2 (PPAR-gamma2): divergent modulating effects on body mass index in obese and lean Caucasian men.
1998-11-01

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

Johan Auwerx, Markku Laakso
1997-04-01

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma

Peter J. Brown
1997-07-01

Incorporation of n-3 fatty acids into plasma lipid fractions, and erythrocyte membranes and platelets during dietary supplementation with fish, fish oil, and docosahexaenoic acid-rich oil among healthy young men

Osmo Hänninen
1992-12-01

Rapid separation of serum lipids for fatty acid analysis by a single aminopropyl column

Makale - wd:Q41189446

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