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Protein dynamics and the allosteric transitions of pentameric receptor channels

author

Jean-Pierre Changeux

1936 -

published in: Biophysical Reviews

date of publication: 2014-11-29

Cites articles 91

Date

Title

Authors

2014-12-18

The nicotinic acetylcholine receptor and its prokaryotic homologues: Structure, conformational transitions & allosteric modulation

Marco Cecchini, Jean-Pierre Changeux
2014-01-01

Allosteric regulation of pentameric ligand-gated ion channels: an emerging mechanistic perspective

Jean-Pierre Changeux, Jérôme Hénin, Marco Cecchini
2014-08-01

X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors

Thorsten Althoff, Surajit Banerjee
2014-08-21

X-ray structure of the mouse serotonin 5-HT3 receptor

Henning Stahlberg, Christophe Moreau, Hugues Nury
2014-10-01

International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands

Arthur Christopoulos, Thomas Burris, John A Cidlowski, Richard Neubig, Jean-Philippe Pin, Patrick M. Sexton, Michael Spedding, Christopher J Langmead, Jean-Pierre Changeux, John A Peters, Doriano Fabbro
2014-07-22

Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein

Jean-Pierre Changeux, M. G. Finn, Katarzyna Kaczanowska
2014-06-08

Crystal structure of a human GABAA receptor

Paul S Miller
2014-05-14

Crystallographic studies of pharmacological sites in pentameric ligand-gated ion channels
2014-04-17

The ensemble nature of allostery

Hesam N Motlagh
2014-02

A unified view of "how allostery works"

Ruth Nussinov, Chung-Jung Tsai
2014-07-12

Analysis of γ-aminobutyric acid (GABA) type A receptor subtypes using isosteric and allosteric ligands.
2013-12-23

Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation

Ahmed Haouz, Marc Delarue, Pierre-Jean Corringer, Jean-Pierre Changeux, Azadeh Shahsavar
2013-01-01

Functional anatomy of an allosteric protein
2013-10-01

Intermediate closed state for glycine receptor function revealed by cysteine cross-linking

Jean-Pierre Changeux
2013-09-20

Nicotinic acetylcholine receptor and the structural basis of neuromuscular transmission: insights from Torpedo postsynaptic membranes
2013-09-16

A gating mechanism of pentameric ligand-gated ion channels

Martin Karplus, Marco Cecchini, Antoine Taly, Jean-Pierre Changeux
2013-08-01

Gating of pentameric ligand-gated ion channels: structural insights and ambiguities
2013-09-20

The concept of allosteric interaction and its consequences for the chemistry of the brain

Jean-Pierre Changeux
2013

Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel

Marc Delarue, Pierre-Jean Corringer, Rebecca J Howard
2013-03-11

Loop C and the mechanism of acetylcholine receptor-channel gating
2013-10-23

50 years of allosteric interactions: the twists and turns of the models.

Jean-Pierre Changeux
2013-09-08

A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors

John Baenziger
2013-06-11

Entropic mechanism of allosteric communication in conformational transitions of dihydrofolate reductase

Tomoki P Terada
2013-05-01

Unraveling the structural basis of GPCR activation and inactivation.

Michel Bouvier
2012-11-23

The nicotinic acetylcholine receptor: the founding father of the pentameric ligand-gated ion channel superfamily
2012-09-13

Conformational transitions underlying pore opening and desensitization in membrane-embedded Gloeobacter violaceus ligand-gated ion channel (GLIC)
2012-05-13

A locally closed conformation of a bacterial pentameric proton-gated ion channel

Marc Delarue, Pierre-Jean Corringer, Marc Baaden, Hugues Nury
2012-04-02

Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals

Giovanni Gonzalez-Gutierrez, Tiit Lukk
2012-01-06

Allostery and the Monod-Wyman-Changeux model after 50 years

Jean-Pierre Changeux
2011-06-02

Principles of activation and permeation in an anion-selective Cys-loop receptor

Eric Gouaux
2011

Decrypting the sequence of structural events during the gating transition of pentameric ligand-gated ion channels based on an interpolated elastic network model

Wenjun Zheng
2011-01-20

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

Marc Delarue, Pierre-Jean Corringer, Jean-Pierre Changeux, Marc Baaden, Hugues Nury

Article - wd:Q41692617

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