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The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing

pengarang

Victor M Bolanos-Garcia

Jakob Nilsson

Tiziana Lischetti

Gang Zhang

diterbitkan dalam: Nature Communications

tanggal publikasi: 2014-12-08

bahasa: Inggris

Cites articles 42

Date

Judul

Pengarang

2014-01-25

Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint

Jamin B Hein, Jakob Nilsson
2013-06-20

Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20

Daniele Fachinetti, Don Cleveland
2013-03-25

BUBR1 recruits PP2A via the B56 family of targeting subunits to promote chromosome congression
2013-01-23

Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression

Jakob Nilsson, Thomas Kruse, Marie Sofie Yoo Larsen, Gang Zhang
2013-01-23

Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex

Mercedes Pardo, Jakob Nilsson, Jonathon Noe Joseph Pines
2012-11-01

The spindle assembly checkpoint

Pablo Lara-Gonzalez, Fred Westhorpe, Stephen S. Taylor
2012-03-21

Structure of the mitotic checkpoint complex

Ziguo Zhang
2012-11-06

Structural analysis of human Cdc20 supports multisite degron recognition by APC/C

Diana R. Tomchick
2012-11-27

Kinetochore localized Mad2 and Cdc20 is itself insufficient for triggering the mitotic checkpoint when Mps1 is low in Drosophila melanogaster neuroblasts

Michael J Taggart
2012-10-01

Integration of kinase and phosphatase activities by BUBR1 ensures formation of stable kinetochore-microtubule attachments.

Saskia J E Suijkerbuijk, Mathijs Vleugel
2011-12-01

Spindle assembly checkpoint: the third decade

Andrea Musacchio
2011-06-02

Cubism and the cell cycle: the many faces of the APC/C.

Jonathon Noe Joseph Pines
2011-12-22

BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner

Pablo Lara-Gonzalez, Onur Sen, Stephen S. Taylor
2011-04-27

BUBR1 and closed MAD2 (C-MAD2) interact directly to assemble a functional mitotic checkpoint complex

Tim J. Yen
2011-11-18

p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit

Fred Westhorpe, Pablo Lara-Gonzalez, Stephen S. Taylor
2010-01-01

Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1.

Zhen Dou, Erich Nigg
2010-06-01

Molecular causes for BUBR1 dysfunction in the human cancer predisposition syndrome mosaic variegated aneuploidy

Nazneen Rahman, Saskia J E Suijkerbuijk, Geert Kops
2010-04-26

Recruitment of Cdc20 to the kinetochore requires BubR1 but not Mad2 in Drosophila melanogaster
2010-12-01

Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase

Manuel Eguren, Marcos Malumbres, Guillermo de Cárcer
2009-01-01

Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding
2009-01-01

BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase
2008-11-09

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

Jonathon Noe Joseph Pines, Jakob Nilsson
2008-06-13

The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C).

Kevin G Hardwick, Kathleen L. Gould
2008-11-07

Structure and Substrate Recruitment of the Human Spindle Checkpoint Kinase Bub1

Mischa Machius, Maojun Yang, Diana R. Tomchick, Wei Qi
2007-04-04

Mad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpoint

Kevin G Hardwick
2007-03-01

Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint
2006-04-04

Spindle checkpoint function requires Mad2-dependent Cdc20 binding to the Mad3 homology domain of BubR1.
2004-07-01

Timing and checkpoints in the regulation of mitotic progression

Patrick Meraldi, Peter K. Sorger
2004-06-01

Spindle checkpoint protein dynamics at kinetochores in living cells

Ben Moree
2004-06-01

Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing

Frank B Furnari, Don Cleveland
2004-08-22

The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpoint

Jonathon Noe Joseph Pines, Claudine Kraft
2002-03

Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex

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