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Exploring the performance of Multifactor Dimensionality Reduction in large scale SNP studies and in the presence of genetic heterogeneity among epistatic disease models

автор

Marylyn D. Ritchie

Digna R. Velez Edwards

Todd L. Edwards

опубликовано в: Human Heredity

дата публикации: 2008-12-15

язык: английский язык

главная тема: снижение размерности

Cites articles 35

Дата

Заголовок

Авторы

2008-05-16

Alternative contingency table measures improve the power and detection of multifactor dimensionality reduction

William S Bush, Marylyn D. Ritchie, Todd L. Edwards
2008-12-01

A comparison of analytical methods for genetic association studies.

David M. Reif, Alison Motsinger-Reif, Marylyn D. Ritchie
2007-04-25

A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence
2007-05-01

A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction.

Jason H. Moore, William S Bush, Marylyn D. Ritchie, Digna R. Velez Edwards, Alison Motsinger-Reif
2007-11-01

Genetic heterogeneity is not as threatening as you might think

Marylyn D. Ritchie, Todd L. Edwards, Alison Motsinger-Reif
2006-01-01

Data simulation software for whole-genome association and other studies in human genetics

Scott M Williams, Digna R. Velez Edwards, Alison Motsinger-Reif, Marylyn D. Ritchie
2006-09-01

The effect of reduction in cross-validation intervals on the performance of multifactor dimensionality reduction.

Marylyn D. Ritchie, Alison Motsinger-Reif
2006-04-20

Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans

Jonathan L Haines, Henry A. Erlich, Stacy J. Caillier, Bruce A C Cree, Lisa F Barcellos, Jorge R. Oksenberg, Stephen L. Hauser, Alison Motsinger-Reif, Marylyn D. Ritchie
2006-07-21

A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility

Chia-Ti Tsai, Fu-Tien Chiang, Jason H. Moore, Nate Barney
2006-01-26

Single-nucleotide polymorphisms for diagnosis of salt-sensitive hypertension

Jason H. Moore, Marylyn D. Ritchie
2006-02-01

A novel method to identify gene-gene effects in nuclear families: the MDR-PDT.

Jason H. Moore, Marylyn D. Ritchie
2006-05-01

An analysis paradigm for investigating multi-locus effects in complex disease: examination of three GABA receptor subunit genes on 15q11-q13 as risk factors for autistic disorder.

Allison Ashley-Koch
2006

Epistatic and pleiotropic effects of polymorphisms in the fibrinogen and coagulation factor XIII genes on plasma fibrinogen concentration, fibrin gel structure and risk of myocardial infarction

Per Eriksson, Anders Hamsten, Angela Silveira, Carl-Göran Ericsson
2005-11-11

A testing framework for identifying susceptibility genes in the presence of epistasis

David V Conti, Frank D Gilliland
2005-11-01

The interaction of four genes in the inflammation pathway significantly predicts prostate cancer risk

Jason H. Moore, Hans-Olov Adami, Henrik Grönberg, Jianfeng Xu, William B Isaacs, Jeffrey Trent, S Lilly Zheng, Baoli Chang, Aubrey R Turner, Fang-Chi Hsu, Jielin Sun, Fredrik Wiklund, James Lowey, Latchezar Dimitrov
2005-09

Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism

Marylyn D. Ritchie
2005-06-01

Traversing the conceptual divide between biological and statistical epistasis: systems biology and a more modern synthesis

Jason H. Moore
2005-11-25

Concordance of multiple analytical approaches demonstrates a complex relationship between DNA repair gene SNPs, smoking and bladder cancer susceptibility.

Heather H. Nelson, Jason H. Moore
2005-07-01

An association study of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA microarray
2005-01-13

Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: complexity in a single-gene disease

Miguel Luz Soares, Alda Sousa, Sergey Batalov, Isabel Conceição, Caroline M Nievergelt, Maria João Saraiva, Joel N Buxbaum, Marylyn D. Ritchie
2005-12-02

Gene-gene interactions for asthma and plasma total IgE concentration in Chinese children

Nelson Leung-Sang Tang
2004-02-01

Routine Discovery of Complex Genetic Models using Genetic Algorithms

Jason H. Moore, Marylyn D. Ritchie
2004-11-01

Computational analysis of gene-gene interactions using multifactor dimensionality reduction

Jason H. Moore
2004-03-15

Renin-angiotensin system gene polymorphisms and atrial fibrillation

Jason H. Moore, Juey-jen Hwang, Chia-Ti Tsai, Ling-Ping Lai, Fu-Tien Chiang, Marylyn D. Ritchie, Jiunn-Lee Lin, Chuen-Den Tseng, Yung-Che Tseng, Kuan-Lih Hsu, Chiau-Suong Liau
2004-03-02

A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other

Dale R Nyholt
2004-01-01

Reporting of model validation procedures in human studies of genetic interactions

Jason H. Moore, Harlan M. Krumholz
2004-01-01

Ideal discrimination of discrete clinical endpoints using multilocus genotypes
2004-01-17

Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus.,Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus

Jason H. Moore, Marylyn D. Ritchie
2004-01-01

Multilocus analysis of hypertension: a hierarchical approach

Scott M Williams, Marshall Summar, Jason H. Moore, Marylyn D. Ritchie
2003-01-01

Confounding, ascertainment bias, and the blind quest for a genetic 'fountain of youth'.
2003-06-01

False discovery rate in linkage and association genome screens for complex disorders.
2003-02-01

Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity

Jason H. Moore, Marylyn D. Ritchie

Статья - wd:Q41972953

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