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The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales

author

Gur Yaari

1972 -

published in: Philosophical Transactions of the Royal Society B

date of publication: 2015-09-01

language: English

Cites articles 30

Date

Title

Authors

2015-06-10

Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data

Gur Yaari
2014-08-01

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

Gur Yaari, George M. Church, David A. Hafler
2014-04-01

High-resolution antibody dynamics of vaccine-induced immune responses

Uri Laserson, Daphne Koller, William Kelton, Birgitte B Simen, Gur Yaari, George M. Church, Erez Lieberman Aiden
2014-03-10

pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires

Gur Yaari, David A. Hafler
2013-12-27

Integrating B cell lineage information into statistical tests for detecting selection in Ig sequences

George M. Church
2013-11-15

Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data

Gur Yaari, David A. Hafler
2013-09-17

Multi Step Selection in Ig H Chains is Initially Focused on CDR3 and Then on Other CDR Regions

Gilad Liberman
2012-05-27

Quantifying selection in high-throughput Immunoglobulin sequencing data sets

Gur Yaari
2012-03-01

Rep-Seq: uncovering the immunological repertoire through next-generation sequencing

Yoram Louzoun, Sol Efroni
2011-06-10

Detecting selection in immunoglobulin sequences

Gur Yaari, Uri Hershberg
2009-11-16

Taking advantage: high-affinity B cells in the germinal center have lower death rates, but similar rates of division, compared to low-affinity cells

Uri Hershberg
2009-05-14

V-region mutation in vitro, in vivo, and in silico reveal the importance of the enzymatic properties of AID and the sequence environment

Thomas MacCarthy, Matthew D Scharff, Aviv Bergman
2008-04-07

Improved methods for detecting selection by mutation analysis of Ig V region sequences

Uri Hershberg
2007-10

The clonal selection theory: 50 years since the revolution

Philip D Hodgkin, William R Heath
2005-10-01

Problems in using statistical analysis of replacement and silent mutations in antibody genes for determining antigen-driven affinity selection

Biplab Bose
2003-11-01

Estimating hypermutation rates from clonal tree data,Estimating Hypermutation Rates from Clonal Tree Data
2003-01-01

IMGT unique numbering for immunoglobulin and T cell receptor variable domains and Ig superfamily V-like domains

Véronique Giudicelli, Marie-Paule Lefranc
2003-09-01

Sequence-specific targeting of two bases on both DNA strands by the somatic hypermutation mechanism
1998-08-01

Predicted and inferred waiting times for key mutations in the germinal centre reaction: evidence for stochasticity in selection.

Thomas B. Kepler
1998-01-01

Conformations of the third hypervariable region in the VH domain of immunoglobulins.

Cyrus Chothia, Anna Tramontano, Arthur M. Lesk
1996-04-01

The molecular basis of somatic hypermutation of immunoglobulin genes
1996-04-01

Di- and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells
1991-12-01

Maturation of the immune response in germinal centers
1989-12-01

Mechanism of antigen-driven selection in germinal centres

Gwyn T Williams
1988-11-01

Stepwise intraclonal maturation of antibody affinity through somatic hypermutation

Klaus Rajewsky
1988-07-01

Antibody engineering for the analysis of affinity maturation of an anti-hapten response
1987-12-01

Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse
1987-08-01

The role of clonal selection and somatic mutation in autoimmunity
1984-05-01

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin
1962-06

On the probability of fixation of mutant genes in a population

Article - wd:Q42015134

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