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Mitochondria and PGC-1α in Aging and Age-Associated Diseases

published in: Journal of Aging Research

date of publication: 2011-05-05

main subject: mitochondrion

Cites articles 144

Date

Title

Authors

2011-02-09

Telomere dysfunction induces metabolic and mitochondrial compromise

Simona Colla, Florian Muller, Darrell N Kotton, Ronald A. DePinho
2011-01-01

Sirt3 targets mPTP and prevents aging in the heart
2011-11-01

A metabolic shift induced by a PPAR panagonist markedly reduces the effects of pathogenic mitochondrial tRNA mutations
2011-04-01

Metformin induces Rab4 through AMPK and modulates GLUT4 translocation in skeletal muscle cells
2011-02-09

Metabolic factors in the development of hepatic steatosis and altered mitochondrial gene expression in vivo
2010-12-01

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy
2010

A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans

Siegfried Hekimi
2010-12-07

GABP controls a critical transcription regulatory module that is essential for maintenance and differentiation of hematopoietic stem/progenitor cells

Hai-Hui Xue
2010-12-01

Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance

Michael J. Jurczak, Peter S. Rabinovitch, Gerald I. Shulman, Varman T Samuel, Dongyan Zhang, Kitt F Petersen, François R Jornayvaz, Andreas Birkenfeld, Warren Ladiges
2010-11-10

At the crossroads of longevity and metabolism: the metabolic syndrome and lifespan determinant pathways

Gian Paolo Fadini, Giulio Ceolotto, Angelo Avogaro, Saula Vigili de Kreutzenberg
2010-10-11

Rosiglitazone attenuates age- and diet-associated nonalcoholic steatohepatitis in male low-density lipoprotein receptor knockout mice

Anisha A. Gupte
2010-10-01

PGC-1 coactivators in cardiac development and disease
2010-09-20

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

Matthew D. Hirschey, Eric Verdin, Marcia C. Haigis, Lydia Finley
2010-08-01

Dietary restriction: standing up for sirtuins

Joseph A. Baur, David Sinclair, Eric Verdin, Stefanie Dimmeler, Blanka Rogina, Junichi Sadoshima, Rafael de Cabo, Manuel Serrano, Christian Neri, Heidi A Tissenbaum, Richard Pestell
2010-08-20

Regulation of autophagy by ROS: physiology and pathology
2010-08-11

SIRT1 activation by small molecules: kinetic and biophysical evidence for direct interaction of enzyme and activator

Thomas Riera
2010-07-22

Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis
2010-07-01

Transient upregulation of PGC-1alpha diminishes cardiac ischemia tolerance via upregulation of ANT1

Edward G Lynn
2010-04-29

Mitochondrial oxidative damage and apoptosis in age-related hearing loss
2010-04-06

PGC-1alpha regulation by exercise training and its influences on muscle function and insulin sensitivity
2010-06

How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)

Kim Zarse, Michael Ristow
2010-03-21

Resveratrol as a therapeutic agent for neurodegenerative diseases
2010-02-24

Regulation of skeletal muscle cell plasticity by the peroxisome proliferator-activated receptor γ coactivator 1α

Christoph Handschin
2010-02-04

PGC-1α and myokines in the aging muscle - a mini-review

Anne-Sophie Arnold, Christoph Handschin
2010-01-25

SIRT1 regulates oxidant- and cigarette smoke-induced eNOS acetylation in endothelial cells: Role of resveratrol
2010

Mammalian sirtuins: biological insights and disease relevance
2010-11-29

Sirt1 acts in association with PPARα to protect the heart from hypertrophy, metabolic dysregulation, and inflammation

Marta Giralt, Francesc Villarroya
2009-12-23

Mechanisms of hematopoietic stem cell aging

Margaret A Goodell
2009-12-04

The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle

Glenn C. Rowe, Jorge L Ruas
2009-11-16

Retracted: Increased muscle PGC-1α expression protects from sarcopenia and metabolic disease during aging

Bruce Spiegelman
2009-11-09

Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis

Peter S. Rabinovitch, Masaru Tanokura, Tatsuya Yamasoba, Richard Weindruch, Tomas A Prolla, Christiaan Leeuwenburgh
2009-11-01

PGC-1alpha activation as a therapeutic approach in mitochondrial disease

Article - wd:Q42738266

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