Inventaire - dine venner og fællesskaber er dit bedste bibliotek

Metabotropic glutamate receptor 5 positive allosteric modulators are neuroprotective in a mouse model of Huntington's disease

forfatter

Grace Schenatto Pereira

Fabiola M Ribeiro

udgivet i: British Journal of Pharmacology

dato for udgivelse: 2013-06-01

sprog: engelsk

main subject: Huntingtons chorea

Cites articles 44

Date

Titel

Forfattere

2012-06-01

Metabotropic glutamate receptors as targets for novel antipsychotic treatments

Anthony J Hannan
2012-01-10

Protective effects of mGluR5 positive modulators against traumatic neuronal injury through PKC-dependent activation of MEK/ERK pathway
2011-02-16

Preclinical profile of a novel metabotropic glutamate receptor 5 positive allosteric modulator
2011-10-31

Angiotensin-(1-7)/Mas axis integrity is required for the expression of object recognition memory

Michael Bader, Grace Schenatto Pereira, Márcio F D Moraes, Natalia Alenina
2010-12-09

Huntington's disease and Group I metabotropic glutamate receptors

Fabiola M Ribeiro
2010-10-05

Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity

Colleen M. Niswender, Craig W. Lindsley, P. Jeffrey Conn, Usha Menon, Alice L. Rodriguez, Emily L Days, Shaun R Stauffer, G Randy Smith, Carrie K Jones
2010-08-01

Animal research: reporting in vivo experiments: the ARRIVE guidelines.

Douglas G. Altman, Innes C. Cuthill
2010-08-01

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

John C. McGrath, Elspeth McLachlan, Cherry L. Wainwright
2010-11-01

Group I metabotropic glutamate receptor signalling and its implication in neurological disease
2010-04-01

Synaptic dysfunction in Parkinson's disease

Veronica Ghiglieri, Carmelo Sgobio, Barbara Picconi
2010-01-01

Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington's disease

Fabiola M Ribeiro
2009-10-01

Intrabody gene therapy ameliorates motor, cognitive, and neuropathological symptoms in multiple mouse models of Huntington's disease
2009-09-08

Effects of positive allosteric modulators on single-cell oscillatory Ca2+ signaling initiated by the type 5 metabotropic glutamate receptor

John Challiss
2009-09-01

Neuronal death in Alzheimer's disease and therapeutic opportunities

Rossen Donev, Martin Kolev, Johannes Thome
2008-12-06

Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

Craig W. Lindsley, P. Jeffrey Conn, Carrie K Jones
2008-06-01

Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice
2008-10-18

Phosphorylation of huntingtin reduces the accumulation of its nuclear fragments

Michael R. Hayden
2005-10-01

Molecular pharmacology and therapeutic prospects of metabotropic glutamate receptor allosteric modulators

Jesper M Mathiesen
2005-08-31

Allosteric potentiators of metabotropic glutamate receptor subtype 5 have differential effects on different signaling pathways in cortical astrocytes

P. Jeffrey Conn
2005-03-01

The scaffold protein Homer1b/c links metabotropic glutamate receptor 5 to extracellular signal-regulated protein kinase cascades in neurons
2005-02-03

Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease

Mutsuyuki Sugimori, Michael R. Hayden, Bruce S Kristal
2005-01-01

Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis

Morten Blaabjerg
2004-03-01

Huntingtin-protein interactions and the pathogenesis of Huntington's disease
2004-09-01

The metabotropic glutamate receptor 5 antagonist MPEP and the mGluR2 agonist LY379268 modify disease progression in a transgenic mouse model of Huntington's disease
2004-07-01

Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression
2003-11

PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis

Solomon H. Snyder
2003-07-17

Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

Michael R. Hayden
2003-07

Regulation of cell death: the calcium-apoptosis link

Sten Orrenius
2003-02

Huntingtin in health and disease
2003-10-01

Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells

Carlos A. Saura, Marcy E. MacDonald
2002-06-01

The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt.

Fabrice P Cordelières
2002-03-01

Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

Oskar Hansson, Michael R. Hayden, Sam Brundin, Blair R Leavitt, Lynn A Raymond, Cheryl L Wellington, Melinda M Zeron

Artikel - wd:Q43120924

Welcome to Inventaire

dit venne- og fællesskabs bibliotek

vil du vide mere