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BRCA1 is a histone-H2A-specific ubiquitin ligase

published in: Cell Reports

date of publication: 2014-08-14

Cites articles 30

Date

Title

Authors

2014-03-06

Nucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling

Poonam Agarwal
2014-01-01

The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A

Francesca Mattiroli, Michael Uckelmann, Titia Sixma
2012-10-18

Shaping chromatin for repair

Anastas Gospodinov
2012-09-14

RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling

Wim Vermeulen, Titia Sixma
2012-05-15

Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation

Dante Neculai, Curtis D Hodge
2011-10-01

BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity
2011-09-07

BRCA1 tumour suppression occurs via heterochromatin-mediated silencing

Hoonkyo Suh, Fred Gage
2011-08-17

Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex

Andrea Cochran
2011-02-18

The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection
2010-03

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

Maria Jasin, Mary Ellen Moynahan
2009-02-06

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

Daniel Durocher, Stephanie Panier, Jan Ellenberg, Jiří Bártek, Jiří Lukáš, Dorthe H Larsen, Claudia Lukas, Simon Bekker-Jensen, Rainer Pepperkok
2009-02-06

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

Daniel Durocher, Stephanie Panier, Grant S Stewart, Anne Durandy, Shinichiro Nakada, Jan Wildenhain, Nadine Kolas, Hakim Ben Abdallah, Jarkko Ylanko, Megan Mendez
2008-12-16

E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks
2007-10

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages
2007-10-01

A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin.

Goedele Maertens, Haruhiko Koseki
2006-07-21

Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex
2006-06-07

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b

Oliver Weichenrieder, Anastassis Perrakis, Titia Sixma
2006-03-01

A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination
2004-10-14

Role of histone H2A ubiquitination in Polycomb silencing

Hediye Erdjument-Bromage, Paul Tempst, Miguel Vidal, Yi Zhang
2004-04-15

BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair

Ellen Solomon
2002-12-16

Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains
2002-04-01

Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase

James L. Manley
2001-10-01

Functions of BRCA1 and BRCA2 in the biological response to DNA damage
2001-10-01

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

Mary-Claire King
2001-05-22

Direct DNA binding by Brca1
2001-04-01

Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity
2001-05-01

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation
2001-05-04

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation
1996-12

Identification of a RING protein that can interact in vivo with the BRCA1 gene product
1980-11-01

Size-dependence of a stable higher-order structure of chromatin.

Article - wd:Q43212891

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