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Effect of CYP1A2 deficiency on heterocyclic amine DNA adduct levels in mice

publicerad i: Food and Chemical Toxicology

utgivningsår: 2002-10-01

Refererar artiklar 26

Datum

Titel

Författare

2001-01-01

Carcinogen substrate specificity of human COX-1 and COX-2.
2000-08-01

2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, a carcinogen in high-temperature-cooked meat, and breast cancer risk

James R Cerhan, Martin Kulldorff
1999-12-01

A new approach to risk estimation of food-borne carcinogens--heterocyclic amines--based on molecular information
1999-03-01

DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis
1997-04-01

Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes
1995-11-01

Possible mechanisms for PhIP-DNA adduct formation in the mammary gland of female Sprague-Dawley rats
1995-01-01

Metabolic polymorphisms and carcinogen-DNA adduct formation in human populations
1995-01-01

Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research
1995-07-01

Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
1995-09-01

Procarcinogen activation by cytochrome P450 3A4 and 3A5 expressed in Escherichia coli and by human liver microsomes.

F. Peter Guengerich
1994-05-01

Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human
1994-08-01

Metabolic activation pathway for the formation of DNA adducts of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat extrahepatic tissues.
1994-08-01

Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes.
1993-01-01

Mutagenic activation of IQ, PhIP and MeIQx by hepatic microsomes from rat, monkey and man: low mutagenic activation of MeIQx in cynomolgus monkeys in vitro reflects low DNA adduct levels in vivo.
1993-10

Expression of CYP1A1 and CYP1A2 genes in human liver
1993-07-01

32P-postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx- and PhIP-treated monkeys.
1993-06-01

Effect of 3-methylcholanthrene induction on the distribution and DNA adduction of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in F344 rats.
1992-12-01

Formation of DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in male Fischer-344 rats
1991-08-01

A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
1991-03-01

Carcinogenicities of heterocyclic amines in cooked food
1990-03-01

Glutathione S-transferase and glutathione peroxidase expression in normal and tumour human tissues

John D. Hayes
1989-01-01

Mutagen activation by cDNA-expressed P(1)450, P(3)450, and P450a
1989-10

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

F. Peter Guengerich
1989-02-01

Selective mutagenic activation by cytochrome P3-450 of carcinogenic arylamines found in foods.
1988-08-01

DNA adduct formation of the carcinogen 2-amino-3-methylimidazo[4,5-f]-quinoline in target tissues of the F-344 rat
1988-11-01

Metabolic activation of pyrolysate arylamines by human liver microsomes; possible involvement of a P-488-H type cytochrome P-450.

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