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Identification of two reactive cysteine residues in the tumor suppressor protein p53 using top-down FTICR mass spectrometry

著者

David J Clarke

この作品が含まれる作品: Journal of the American Society for Mass Spectrometry

出版日: 2011-02-24

Cites articles 51

Date

タイトル

著者

2010-01-01

Differential regulation of p53 target genes: it's (core promoter) elementary

Nathan Gomes, Joaquín M Espinosa
2010-03-16

Targeted quantitation of site-specific cysteine oxidation in endogenous proteins using a differential alkylation and multiple reaction monitoring mass spectrometry approach

Jason M. Held, Judith Campisi
2010-03-08

15-Deoxy-Delta(12,14)-prostaglandin J(2) stabilizes, but functionally inactivates p53 by binding to the cysteine 277 residue
2010-12-01

Stabilization of mutant p53 via alkylation of cysteines and effects on DNA binding

Alan Fersht, Andreas C Joerger
2009-10-01

The first 30 years of p53: growing ever more complex

Moshe Oren
2009-09-01

Effect of thioredoxin deletion and p53 cysteine replacement on human p53 activity in wild-type and thioredoxin reductase null yeast
2009-08-29

Mutant p53 rescue and modulation of p53 redox state

Pierre Hainaut, Klas Wiman, Vladimir J N Bykov
2009-05-01

PRIMA-1 reactivates mutant p53 by covalent binding to the core domain

Alan Fersht, Klas Wiman, Pierre Hainaut, Dmitry B Veprintsev, Vladimir J N Bykov
2009-08-21

Effects of stability on the biological function of p53.

Alan Fersht
2009-01-01

Tandem mass spectrometry with ultrahigh mass accuracy clarifies peptide identification by database retrieval

Craig D Wenger, Neil Kelleher
2008-01-01

Structural biology of the tumor suppressor p53.

Alan Fersht, Andreas C Joerger
2008-01-26

ROS and p53: a versatile partnership
2008-02-09

The p73 DNA binding domain displays enhanced stability relative to its homologue, the tumor suppressor p53, and exhibits cooperative DNA binding.

Franca Fraternali
2008-08-02

Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax.

Franca Fraternali, John E. Ladbury
2007-04-01

p53 in health and disease

David P. Lane, Karen Vousden
2007-11-19

A role for DNA-mediated charge transport in regulating p53: Oxidation of the DNA-bound protein from a distance

ジャクリン・バートン
2007-10-01

Decoding protein modifications using top-down mass spectrometry
2007-03

Structure of the human p53 core domain in the absence of DNA

Hartmut Luecke
2007-06-08

Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress

Kalkunte Srivenugopal
2007-03-05

The MDM2 ubiquitination signal in the DNA-binding domain of p53 forms a docking site for calcium calmodulin kinase superfamily members
2007-10

ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
2006-07-01

Quantitative analysis of modified proteins and their positional isomers by tandem mass spectrometry: human histone H4

James J Pesavento
2005-08

Complicating the complexity of p53

Karen Vousden
2005

Proteomics by FTICR mass spectrometry: top down and bottom up

Richard D. Smith
2005-03-01

Detection and localization of protein modifications by high resolution tandem mass spectrometry
2005-07-01

Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs

Galina Selivanova, Klas Wiman, Vladimir J N Bykov, Natalia Issaeva, Alexandre Shilov
2005

Collision-induced dissociation (CID) of peptides and proteins,Collision‐Induced Dissociation (CID) of Peptides and Proteins
2004-07-01

ProSight PTM: an integrated environment for protein identification and characterization by top-down mass spectrometry
2004-01-09

Crystal structure of a superstable mutant of human p53 core domain. Insights into the mechanism of rescuing oncogenic mutations

Alan Fersht, Andreas C Joerger
2004-06-01

Top-down proteomics
2003-10-01

Formation of disulfide bond in p53 correlates with inhibition of DNA binding and tetramerization
2003-01-01

Thiol alkylation inhibits the mitogenic effects of platelet-derived growth factor and renders it proapoptotic via activation of STATs and p53 and induction of expression of caspase1 and p21(waf1/cip1).

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