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Exploring the pathophysiology of hypogonadism in men with type 2 diabetes: kisspeptin-10 stimulates serum testosterone and LH secretion in men with type 2 diabetes and mild biochemical hypogonadism

author

Jyothis T George

Manuel Tena-Sempere

Robert P. Millar

1944 -

Johannes D Veldhuis

published in: Clinical Endocrinology

date of publication: 2013-04-19

main subject: type 2 diabetes, hypogonadism, pathophysiology, testosterone, testosterone

Cites articles 17

Date

Title

Authors

2012-05-21

Emerging medication for the treatment of male hypogonadism.

Giovanni Corona, Mario Maggi, Giulia Rastrelli, Linda Vignozzi
2012-09-19

Analysis of the impact of intravenous LH pulses versus continuous LH infusion on testosterone secretion during GnRH-receptor blockade

Johannes D Veldhuis
2012-09-26

Kisspeptin and the hypothalamic control of reproduction: lessons from the human

Jyothis T George, Stephanie B Seminara
2011-09-01

Update: Hypogonadotropic hypogonadism in type 2 diabetes and obesity
2011-06-01

Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men

Jyothis T George, Antonia K Roseweir, Claire Newton, Elena Faccenda, Robert P. Millar
2010-06-10

Hypothesis: kisspeptin mediates male hypogonadism in obesity and type 2 diabetes

Jyothis T George, Robert P. Millar
2010

Human GnRH deficiency: a unique disease model to unravel the ontogeny of GnRH neurons

Andrew A Dwyer, Nelly Pitteloud, Stephanie B Seminara, William F. Crowley, Ravikumar Balasubramanian
2009-06-16

Sensitivity and specificity of pulse detection using a new deconvolution method

Johannes D Veldhuis
2008-07-01

Decreased expression of kisspeptin mediates acute immune/inflammatory stress-induced suppression of gonadotropin secretion in female rat.
2008-10-21

Motivations and methods for analyzing pulsatile hormone secretion

Johannes D Veldhuis
2006-09-01

Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats.

Juan Manuel Castellano, Juan Roa, Manuel Tena-Sempere
2004-11-01

Frequent occurrence of hypogonadotropic hypogonadism in type 2 diabetes
2004-04

Gonadotropin-releasing hormone receptors

Zhi-Liang Lu, Colleen A Flanagan, Adam J Pawson, Robert P. Millar
2004-07-08

Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide

Juan Roa, Manuel Tena-Sempere, Juan Manuel Castellano
2003-10-23

The GPR54 gene as a regulator of puberty

Wendy Kuohung, Alan Hendrick, William H. Colledge, Stephen O'Rahilly, James F. Gusella, Stephanie B Seminara, William F. Crowley
2003-09-16

Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54

Edwin Milgrom
2000-12-01

Long-term pharmacokinetics of transdermal testosterone gel in hypogonadal men.

Article - wd:Q45359713

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