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Fibronectin is a stress responsive gene regulated by HSF1 in response to geldanamycin.

author

Adrienne L. Edkins

William John Samson

published in: Scientific Reports

date of publication: 2017-12-15

language: English

Cites articles 77

Date

Title

Authors

2016-10-17

High expression of fibronectin is associated with poor prognosis, cell proliferation and malignancy via the NF-κB/p53-apoptosis signaling pathway in colorectal cancer
2016-03-23

Mammalian Heat Shock Response and Mechanisms Underlying Its Genome-wide Transcriptional Regulation
2015-12-26

Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration

Jörg Rahnenführer, Jan G Hengstler, Marcel Leist, Agapios Sachinidis
2015-11-09

Molecular Mechanism Responsible for Fibronectin-controlled Alterations in Matrix Stiffness in Advanced Chronic Liver Fibrogenesis

Riaz Akhtar
2015-05-22

Glucose regulates heat shock factor 1 transcription activity via mTOR pathway in HCC cell lines
2014-11-17

A community computational challenge to predict the activity of pairs of compounds

Mukesh Bansal, Tao Wang, Michela Mattioli, Julio Saez-Rodriguez, Gustavo Stolovitzky, Andrea Califano, Charles Karan, Guanghua Xiao, Ronald Realubit, Laura M Heiser
2014-10-06

High glucose forces a positive feedback loop connecting Akt kinase and FoxO1 transcription factor to activate mTORC1 kinase for mesangial cell hypertrophy and matrix protein expression
2014-07-01

The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

Marc Mendillo, Susan Lindquist, Luke Whitesell, Sandro Santagata, Dora Dias-Santagata
2014

Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells

Kyle L O'Hagan, Earl Prinsloo, Adrienne L. Edkins
2014-06-16

Inhibition of fibronectin deposition improves experimental liver fibrosis.
2014-02-05

Identification of citrullinated cellular fibronectin in synovial fluid from patients with rheumatoid arthritis
2013-08-01

Circulating fibronectin controls tumor growth

Justo Lorenzo Bermejo, Sarah Schott, Peter Sinn
2013-07-01

Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state

Angelika Amon, Marc Mendillo, Susan Lindquist, Luke Whitesell, Todd Golub, Sandro Santagata
2013-04-06

SDF-1α reduces fibronectin expression in rat mesangial cells induced by TGF-β1 and high glucose through PI3K/Akt pathway
2012-10-30

Affordable luciferase reporter assay for cell-based high-throughput screening

Michael Howell
2012-08-31

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition

Susan Lindquist, Georgios I. Karras, Can Kayatekin, Mikko Taipale, Kenneth D Westover, Irina Krykbaeva
2012-08-01

HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers

Marc Mendillo, Susan Lindquist, Luke Whitesell, George W Bell, Rulla M Tamimi, Sandro Santagata, Ernest Fraenkel
2012-06-29

mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis

Jianlin Gong
2012-03-01

S1P2 receptor mediates sphingosine-1-phosphate-induced fibronectin expression via MAPK signaling pathway in mesangial cells under high glucose condition
2012-01-01

Hsp90 molecular chaperone inhibitors: are we there yet?

Paul Workman, Len Neckers
2012-03

Quality control and fate determination of Hsp90 client proteins
2012-12-19

Heat shock protein 90 (HSP90) inhibitors activate the heat shock factor 1 (HSF1) stress response pathway and improve glucose regulation in diabetic mice
2011-12-24

HSP90 as a platform for the assembly of more effective cancer chemotherapy

Luke Whitesell, Nancy U Lin
2011-11-01

Cancer invasion and the microenvironment: plasticity and reciprocity

Peter Friedl, Stephanie Alexander
2011-12-01

Extracellular matrix degradation and remodeling in development and disease

Zena Werb, Valerie M Weaver
2011-04-03

Essential roles of fibronectin in the development of the left-right embryonic body plan

Richard Hynes
2011

Regulation of HSF1 function in the heat stress response: implications in aging and disease
2011-03

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
2011-03-15

A phase I study of the heat shock protein 90 inhibitor alvespimycin (17-DMAG) given intravenously to patients with advanced solid tumors

Paul Workman, Anthea Hardcastle, Simon Pacey, Wynne Aherne, Florence Raynaud, Ian Judson
2011-01-12

Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease

David M. Holtzman, John C. Morris, Anne M Fagan, Catherine M Roe, Richard J Perrin, D Galasko, Elaine Peskind, Rebecca Craig-Schapiro, R Reid Townsend, Joseph Quinn, Jeffrey Kaye, Petra Erdmann-Gilmore
2011-08-25

Heat shock factor 1 promotes invasion and metastasis of hepatocellular carcinoma in vitro and in vivo.
2010-11-15

KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter

Article - wd:Q46756566

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