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LDL receptor blockade reduces mortality in a mouse model of ischaemic stroke without improving tissue-type plasminogen activator-induced brain haemorrhage: towards pre-clinical simulation of symptomatic ICH.

forfatter

Be'eri Niego

Christopher G Sobey

Brad R S Broughton

udgivet i: Fluids and Barriers of the CNS

dato for udgivelse: 2017-11-21

Cites articles 47

Date

Titel

Forfattere

2017-05-16

Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin

Be'eri Niego, Travice De Silva
2017-01-27

Plasma kallikrein mediates brain hemorrhage and edema caused by tissue plasminogen activator therapy in mice after stroke

Fabrício Simão, Edward P Feener
2017-07-01

Regulatory T cells ameliorate tissue plasminogen activator-induced brain haemorrhage after stroke

Yanling Wang, Rehana K. Leak, Jun Chen
2017-04-20

Toll-Like Receptor 4 Mediates Hemorrhagic Transformation After Delayed Tissue Plasminogen Activator Administration in In Situ Thromboembolic Stroke.

María Ángeles Moro Sánchez, Ignacio Lizasoain, Alicia García-Culebras, María I Cuartero
2016-08-16

Hyperfibrinolysis increases blood-brain barrier permeability by a plasmin- and bradykinin-dependent mechanism

Joan Montaner, Denis Vivien, Maxime Gauberti
2016

A Review of the Mechanisms of Blood-Brain Barrier Permeability by Tissue-Type Plasminogen Activator Treatment for Cerebral Ischemia
2016-01-27

Rapid endothelial cytoskeletal reorganization enables early blood-brain barrier disruption and long-term ischaemic reperfusion brain injury

Yejie Shi, Xiaoyan Jiang, Rehana K. Leak, Richard F. Keep, Jun Chen
2015-07

Management of Postthrombolysis Hemorrhagic and Orolingual Angioedema Complications
2015-07-29

Recombinant tissue-type plasminogen activator transiently enhances blood-brain barrier permeability during cerebral ischemia through vascular endothelial growth factor-mediated endothelial endocytosis in mice
2015-02-17

Receptor-associated protein promotes t-PA expression, reduces PAI-1 expression and improves neurorecovery after acute ischemic stroke

Dan-dong Li
2014-09-01

Symptomatic intracerebral hemorrhage in acute ischemic stroke after thrombolysis with intravenous recombinant tissue plasminogen activator: a review of natural history and treatment
2014-06-04

Plasmin-dependent modulation of the blood-brain barrier: a major consideration during tPA-induced thrombolysis?

Be'eri Niego
2014-01-23

Sex-dependent effects of G protein-coupled estrogen receptor activity on outcome after ischemic stroke

Grant R. Drummond, Vanessa Brait, Hyun Ah Kim, Christopher G Sobey, Brad R S Broughton
2013-09-18

Progesterone attenuates hemorrhagic transformation after delayed tPA treatment in an experimental model of stroke in rats: involvement of the VEGF-MMP pathway
2013-03-01

Complications associated with recombinant tissue plasminogen activator therapy for acute ischaemic stroke

Brad A. Sutherland
2012-08-01

Symptomatic intracranial hemorrhage following intravenous thrombolysis for acute ischemic stroke: a critical review of case definitions

Alejandro A. Rabinstein
2012-07-20

The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans

Maithili Sashindranath, Andre L. Samson, Catriona A. McLean, Maria Cristina Morganti-Kossmann, Daniel A. Lawrence, Jeffrey V Rosenfeld
2012-06-16

A Rho kinase (ROCK) inhibitor, fasudil, prevents matrix metalloproteinase-9-related hemorrhagic transformation in mice treated with tissue plasminogen activator.
2012-01-19

t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes

Ann M. Turnley, Be'eri Niego, Till B Puschmann
2011-04-12

Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption
2010-12-06

Phosphodiesterase-III inhibitor prevents hemorrhagic transformation induced by focal cerebral ischemia in mice treated with tPA

Yasuyuki Fujiwara, Huayue Chen
2010-05-01

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

Geoffrey A. Donnan, Markku Kaste, Graham Byrnes, Christopher Levi, Thomas G Brott, Yannick Béjot, Helle K Iversen
2010-11-24

A mouse model of hemorrhagic transformation by delayed tissue plasminogen activator administration after in situ thromboembolic stroke

María del Mar Castellanos, Ignacio Lizasoain, María Ángeles Moro Sánchez
2009-08-05

Structure and function of the blood-brain barrier

Adjanie Patabendige, Siti R Yusof
2009-07-16

Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein
2009-08-12

Microglial low-density lipoprotein receptor-related protein 1 mediates the effect of tissue-type plasminogen activator on matrix metalloproteinase-9 activity in the ischemic brain.
2009-07-28

Effect of internal carotid artery reperfusion in combination with Tenecteplase on clinical scores and hemorrhage in a rabbit embolic stroke model

Paul A. Lapchak
2008-09-15

Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function

David Croucher, Andre L. Samson, Daniel A. Lawrence, Be'eri Niego
2008-07-01

LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies
2008-06-22

Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke

Christer Betsholtz
2008-12-18

Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator
2008-09-19

Effect of the duration of middle cerebral artery occlusion on the risk of hemorrhagic transformation after tissue plasminogen activator injection in rats.

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