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The Role of PAR2 in TGF-β1-Induced ERK Activation and Cell Motility.

автор

Frank Gieseler

1958 -

Bernhard H Rauch

опубликовано в: International Journal of Molecular Sciences

дата публикации: 2017-12-20

язык: английский язык

Cites articles 36

Дата

Заголовок

Авторы

2017-08-25

Transforming Growth Factor-β1/Activin Receptor-like Kinase 5-Mediated Cell Migration is Dependent on the Protein Proteinase-Activated Receptor 2 but not on Proteinase-Activated Receptor 2-Stimulated Gq-Calcium Signaling

Bernhard H Rauch, Frank Gieseler
2017-04-03

TGFβ engages MEK/ERK to differentially regulate benign and malignant pancreas cell function

Carolina Torres, Ming-Sound Tsao
2017-12-11

Negative regulation of TGF-β1-induced MKK6-p38 and MEK-ERK signalling and epithelial-mesenchymal transition by Rac1b
2017-02-07

Biased Signaling by Agonists of Protease Activated Receptor 2.

Junxian Lim, Jacky Y. Suen, David P. Fairlie
2016-11-30

Proteinase-Activated Receptor 2 Is a Novel Regulator of TGF-β Signaling in Pancreatic Cancer

Frank Gieseler, Bernhard H Rauch
2016-08-04

Extracellular vesicles from malignant effusions induce tumor cell migration: inhibitory effect of LMWH tinzaparin

Frank Gieseler
2016

Mechanisms of TGFβ-Induced Epithelial-Mesenchymal Transition
2016-05-27

Proteinase-activated receptor 2 promotes TGF-β-dependent cell motility in pancreatic cancer cells by sustaining expression of the TGF-β type I receptor ALK5.

Bernhard H Rauch
2016-03-04

Presenilin 1 promotes trypsin-induced neuroprotection via the PAR2/ERK signaling pathway. Effects of presenilin 1 FAD mutations

Angeliki Nikolakopoulou
2016

Role of EMT in Metastasis and Therapy Resistance
2015-11-30

Factor VII promotes hepatocellular carcinoma progression through ERK-TSC signaling

Anthony Dorling
2015-05-25

Transforming growth factor-β1 induces EMT by the transactivation of epidermal growth factor signaling through HA/CD44 in lung and breast cancer cells
2014-07-12

Vicious cycle of TGF-β signaling in tumor progression and metastasis
2014-07-02

Pathway-selective antagonism of proteinase activated receptor 2.

Jacky Y. Suen, Rink-Jan Lohman, Junxian Lim, Mei-Kwan Yau, Ligong Liu, Matthew A. Cooper, David A Vesey, David P. Fairlie
2014-01-01

Perspectives of TGF-β inhibition in pancreatic and hepatocellular carcinomas

Louis de Mestier, Jérôme Cros, Sandrine Faivre
2013-11-19

Proteinase-activated receptor-2 transactivation of epidermal growth factor receptor and transforming growth factor-β receptor signaling pathways contributes to renal fibrosis

Rithwik Ramachandran
2013-11-11

Proteinase-activated receptors (PARs) - focus on receptor-receptor-interactions and their physiological and pathophysiological impact

Frank Gieseler
2013-04-25

TF/FVIIa/PAR2 promotes cell proliferation and migration via PKCα and ERK-dependent c-Jun/AP-1 pathway in colon cancer cell line SW620.
2012-12-12

Involvement of PKCα activation in TF/VIIa/PAR2-induced proliferation, migration, and survival of colon cancer cell SW620.
2012-08-06

Tgf-beta induced Erk phosphorylation of smad linker region regulates smad signaling
2012-01-03

Targeting proteinase-activated receptors: therapeutic potential and challenges

Rithwik Ramachandran
2012-03-01

Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110)

Jacky Y. Suen, Rink-Jan Lohman, David P. Fairlie
2011-11-24

Tumor-promoting functions of transforming growth factor-β in progression of cancer

Shogo Ehata
2011-05-28

Involvement of ERK1/2/NF-κB signal transduction pathway in TF/FVIIa/PAR2-induced proliferation and migration of colon cancer cell SW620.
2011-05-16

Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2)

Rithwik Ramachandran, Michel Bouvier
2011-01-26

Structure, function and pathophysiology of protease activated receptors

Rithwik Ramachandran, Mei-Kwan Yau, Jacky Y. Suen, David P. Fairlie, John D Hooper
2010-06-01

TGFbeta signalling: a complex web in cancer progression
2010-06-01

PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology
2010-11-01

Phosphorylation of ERK in the spinal dorsal horn following pancreatic pronociceptive stimuli with proteinase-activated receptor-2 agonists and hydrogen sulfide in rats: evidence for involvement of distinct mechanisms
2009-01-01

Roles of TGFbeta in metastasis
2008-09-05

Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: a novel paradigm for receptor cooperativity

Alessio Fasano, Stefanie N. Vogel
2007-09-05

TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

David Warburton

Статья - wd:Q47277683

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