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Integrin α4β7 expression on peripheral blood CD4+ T cells predicts HIV acquisition and disease progression outcomes.

এতে প্রকাশিত: Science Translational Medicine

তারিখে প্রকাশিত: 2018-01-01

ভাষা: ইংরেজি ভাষা

Cites articles 47

তারিখ

শিরোনাম

লেখকগণ

2017-08-17

Progress towards non-invasive diagnosis and follow-up of celiac disease in children; a prospective multicentre study to the usefulness of plasma I-FABP.
2016-02-01

Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques

Kirk Easley, Nicolas Chomont, Mirko Paiardini, Luca Micci
2016-05-30

Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

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2016-10-01

Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy

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2015-04-15

Identification of preferential CD4+ T-cell targets for HIV infection in the cervix

Lyle McKinnon
2015-04-21

Genital inflammation and the risk of HIV acquisition in women

Quarraisha Karim, W. Ian Lipkin, Anneke C. Grobler, Vivek Naranbhai, Katharina Ronacher, Mady Hornig, Gerhard Walzl, Salim Abdool Karim, Douglas A. Lauffenburger, Cheryl Baxter, Lise Werner, Carolyn Williamson, Jo-Ann S Passmore, Lindi Masson, Brent L Williams
2015-04-01

Impact of nucleic acid testing relative to antigen/antibody combination immunoassay on the detection of acute HIV infection

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2015-06-01

Soluble CD14 is a nonspecific marker of monocyte activation
2015-06-24

South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication

Quarraisha Karim, Constantinos Kurt Wibmer, পেনি মুর, Elin S Gray, Salim Abdool Karim, Simone I Richardson, Lise Werner, Lynn Morris, Carolyn Williamson, Nigel Garrett, Jo-Ann S Passmore, Lindi Masson, Daniel J Sheward, Nonhlanhla N Mkhize, Bronwen E Lambson
2015-06-29

CD4:CD8 ratio as a frontier marker for clinical outcome, immune dysfunction and viral reservoir size in virologically suppressed HIV-positive patients

Vikram Mehraj, Jean-Pierre Routy
2015-08-01

Integrin α4β7 Expression Increases HIV Susceptibility in Activated Cervical CD4+ T Cells by an HIV Attachment-Independent Mechanism
2015-10-12

Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

Jinal Bhiman, Jason Gorman, পেনি মুর, Salim Abdool Karim, John R. Mascola, Lynn Morris, Carolyn Williamson, Peter D. Kwong, Nicole Doria-Rose, Chaim A. Schramm, Nigel Garrett, Lawrence Shapiro
2015-12-01

Identification of New Regions in HIV-1 gp120 Variable 2 and 3 Loops that Bind to α4β7 Integrin Receptor

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2014-04-21

Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection

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2014-07-09

Envelope glycoprotein binding to the integrin α4β7 is not a general property of most HIV-1 strains

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2014-07-17

Rapid disease progression in HIV-1 subtype C-infected South African women

Lyle McKinnon, Clive M. Gray, Francois van Loggerenberg, Lise Werner, Lynn Morris, Carolyn Williamson, Jo-Ann S Passmore, Salim Abdool Karim, Koleka Mlisana, Nigel Garrett
2014-11-24

Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection

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2014-12-11

Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation

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2014-12-10

Binding of HIV-1 virions to α4β 7 expressing cells and impact of antagonizing α4β 7 on HIV-1 infection of primary CD4+ T cells

Robin Shattock
2013

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

Jean-Philippe Julien, Alejandra Ramos, Jeong Hyun Lee, Katie Doores, Ian Andrew Wilson, Pascal Poignard, Dennis R. Burton, অ্যান্ড্রু বি ওয়ার্ড, Rogier W Sanders, জন পি মুর, Robyn L Stanfield, Devin Sok, Albert Cupo, Robert Pejchal, Reza Khayat, Rafael S Depetris, Umesh Katpally, Andre J Marozsan
2013-05-29

A novel acute HIV infection staging system based on 4th generation immunoassay

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2013-12-01

The frequency of α₄β₇(high) memory CD4⁺ T cells correlates with susceptibility to rectal simian immunodeficiency virus infection

Natalia Guerra-Perez, James Arthos, Agegnehu Gettie, Jeffrey Lifson, Michael Piatak
2013-08-01

Vedolizumab as induction and maintenance therapy for ulcerative colitis

Gert Van Assche, Paul Rutgeerts, William Jeffery Sandborn, Brian G. Feagan, Jean-Frédéric Colombel, Gerald W Dryden, Silvio Danese, Bruce E. Sands, Stephen B Hanauer, Catherine Milch, Serap Sankoh, Asit Parikh, GEMINI 1 Study Group
2013-08-01

Vedolizumab as induction and maintenance therapy for Crohn's disease

Paul Rutgeerts, Richard N. Fedorak, Milan Lukáš, William Jeffery Sandborn, Brian G. Feagan, Jean-Frédéric Colombel, Gerald W Dryden, Bruce E. Sands, Stephen B Hanauer, Catherine Milch, Serap Sankoh, Asit Parikh, GEMINI 1 Study Group, Brian Bressler
2012-03-01

Quality and quantity: mucosal CD4+ T cells and HIV susceptibility

Lyle McKinnon, Rupert Kaul
2012-04-01

Immune-correlates analysis of an HIV-1 vaccine efficacy trial

Yunda Huang, Guido Ferrari, Jaranit Kaewkungwal, Merlin L Robb, Nelson Michael, Jerome H Kim, Supachai Rerks-Ngarm, Richard A Koup, Georgia D. Tomaras, Nicole Yates, Barton Haynes, Julie McElrath, পিটার বি গিলবার্ট, Erik A Billings, David C. Montefiori, Viseth Ngauy, Sorachai Nitayaphan, Punnee Pitisuttithum, Nicole Frahm, Nicos Karasavvas, Shreya Rosa Stephen, Kelly A Soderberg, Susan Zolla-Pazner, Munir Alam, Chitraporn Karnasuta, Youyi Fong, Allan C deCamp, Charla A Andrews, Phillip W Berman, Anthony L DeVico, জর্জ কে লুইস, Hua-Xin Liao, Mangala Rao, Abraham Pinter
2011-02-24

The genotype of early-transmitting HIV gp120s promotes α (4) β(7)-reactivity, revealing α (4) β(7) +/CD4+ T cells as key targets in mucosal transmission

অ্যান্টনি ফৌসি, Claudia Cicala, James Arthos
2011-03-07

Recruitment of high risk women for HIV prevention trials: baseline HIV prevalence and sexual behavior in the CAPRISA 004 tenofovir gel trial

Quarraisha Karim, Anneke C. Grobler, Tanuja N. Gengiah, Koleka Mlisana, Salim Abdool Karim, Cheryl Baxter, Natasha Samsunder, Sengeziwe Sibeko
2011-11-02

Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility

Lyle McKinnon, Joshua Kimani, Rupert Kaul, Claudia Cicala, James Arthos, Duncan Chege, Sanja Huibner, Lawrence J Gelmon, Makobu Kimani, Omu Anzala, Billy Nyanga, Preston Izulla
2010-06-01

Non-invasive markers for early diagnosis and determination of the severity of necrotizing enterocolitis

Boris W Kramer
2010-12-13

Blocking of α4β7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques

Aftab A. Ansari, Francois Villinger, Ann E Mayne
2011-01-27

HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV

অ্যান্টনি ফৌসি, Claudia Cicala, James Arthos

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