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Sumoylation: Implications for Neurodegenerative Diseases

author

Jeremy M. Henley

Helena Cimarosti

published in: Advances in Experimental Medicine and Biology

date of publication: 2017-01-01

language: English

main subject: neurodegeneration

Cites articles 138

Date

Title

Authors

2016-03-02

SUMO-regulated mitochondrial function in Parkinson's disease
2016-02

Identification of new SUMO activating enzyme 1 inhibitors using virtual screening and scaffold hopping

Minoru Yoshida
2015-01-21

Extent of inhibition of α-synuclein aggregation in vitro by SUMOylation is conjugation site- and SUMO isoform-selective

Matthew R Pratt
2015-01-01

SUMO1 promotes Aβ production via the modulation of autophagy
2015-08-01

Plasma SUMO1 Protein is Elevated in Alzheimer's Disease.
2015-01-20

Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease

Jorge Iñiguez-lluhí
2015-01-20

Fighting polyglutamine disease by wrestling with SUMO.

Jeremy M. Henley, Tim J Craig
2015-09

SUMOylation: Novel Neuroprotective Approach for Alzheimer's Disease?

Helena Cimarosti
2015-03-17

Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation

Armin Giese, Wiebke Möbius, Markus Zweckstetter, Ruth Geiss-Friedlander, Mikael Simons, Johannes Levin, Brit Mollenhauer, Albert C. Ludolph, Anja Schneider, Sebastian Kügler
2015-07-31

Battling Alzheimer's Disease: Targeting SUMOylation-Mediated Pathways

Carla I Tasca, Helena Cimarosti
2015-07-24

Direct and/or Indirect Roles for SUMO in Modulating Alpha-Synuclein Toxicity

Shamini Vijayakumaran, Mathew B Wong
2014-04-21

Sumoylation of the astroglial glutamate transporter EAAT2 governs its intracellular compartmentalization
2014-05-29

A cellular system that degrades misfolded proteins and protects against neurodegeneration

James Shorter, Aaron D Gitler
2014-10-01

Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction

Jeremy M. Henley, Tim J Craig, Kevin A Wilkinson
2014-02-19

Identification of 1,2,5-oxadiazoles as a new class of SENP2 inhibitors using structure based virtual screening

Minoru Yoshida
2014-12-02

Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease

Mauro Fà, Ottavio Arancio
2014-06-27

SUMO3 modification accelerates the aggregation of ALS-linked SOD1 mutants

Yoichiro Abe
2014-09-17

Interplay between sumoylation and phosphorylation for protection against α-synuclein inclusions

Gerhard H Braus, Blagovesta Popova, Tiago Fleming Outeiro
2014-06-25

The Role of SUMO-Conjugating Enzyme Ubc9 in the Neuroprotection of Isoflurane Preconditioning Against Ischemic Neuronal Injury

Yu Zong Chen
2013-08-25

SUMO and Parkinson's disease
2013-12

Sumoylation of critical proteins in amyotrophic lateral sclerosis: emerging pathways of pathogenesis
2013-03-22

SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia

Jeremy M. Henley, Laura Dearden, Kevin A Wilkinson
2013-05-04

SUMO-1 conjugation blocks beta-amyloid-induced astrocyte reactivity

Marcus Rattray, Helena Cimarosti
2013-06-18

SUMO and ischemic tolerance
2013-07-19

Molecular targets underlying SUMO-mediated neuroprotection in brain ischemia
2013-04-11

Increased SUMO-1 expression in the unilateral rotenone-lesioned mouse model of Parkinson's disease

Mathew B Wong
2012-09-25

Sumoylation in neurodegenerative diseases
2012-09-12

Moderate hypothermia induces marked increase in levels and nuclear accumulation of SUMO2/3-conjugated proteins in neurons
2012-04-30

Correlation of increased hippocampal Sumo3 with spatial learning ability in old C57BL/6 mice.
2012-09-11

SUMO1 modulates Aβ generation via BACE1 accumulation

Keejung Yoon, Rudolph E. Tanzi, Eui-Ju Choi
2012-07-03

Discovery of 1-[4-(N-benzylamino)phenyl]-3-phenylurea derivatives as non-peptidic selective SUMO-sentrin specific protease (SENP)1 inhibitors

Hyun Seung Ban, Hiroyuki Nakamura
2012-03-15

SENP1 deficiency promotes ER stress-induced apoptosis by increasing XBP1 SUMOylation

Article - wd:Q47799714

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