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Gi- and Gs-coupled GPCRs show different modes of G-protein binding.

author

Scott A Hollingsworth

Ron Ofer Dror

Oliver Ernst

published in: Proceedings of the National Academy of Sciences of the United States of America

date of publication: 2018-02-20

language: English

Cites articles 59

Date

Title

Authors

2017-05-24

Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein

Georgios Skiniotis, Brian Kobilka, Yan Zhang, Tong Sun Kobilka
2017-04-03

Conformational equilibria of light-activated rhodopsin in nanodiscs

Wayne L. Hubbell, Klaus Peter Hofmann
2017-05-10

Selectivity determinants of GPCR-G-protein binding.

David E. Gloriam, Tilman Flock, Alexander S Hauser
2017-04-24

Phase-plate cryo-EM structure of a class B GPCR-G-protein complex

Thomas Coudrat, Denise Wootten, Georgios Skiniotis, Brian Kobilka, Yan Zhang, David M Thal, Arthur Christopoulos, Alisa Glukhova
2016-11-07

CHARMM36m: an improved force field for folded and intrinsically disordered proteins

Jing Huang, Michael Feig, Alexander D. MacKerell
2016-07-27

Structure of the adenosine A(2A) receptor bound to an engineered G protein

Byron Carpenter, Tony Warne
2016-05-04

Activation of the A2A adenosine G-protein-coupled receptor by conformational selection

Oliver Ernst
2015-06-01

SIGNAL TRANSDUCTION. Structural basis for nucleotide exchange in heterotrimeric G proteins

David W. Borhani, Brian Kobilka, Aashish Manglik, Wayne L. Hubbell, Ron Ofer Dror
2015-05-14

Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling

Brian Kobilka, Aashish Manglik, Wayne L. Hubbell, Tong Sun Kobilka
2015-03-30

Long-Time-Step Molecular Dynamics through Hydrogen Mass Repartitioning.

Adrian Roitberg
2015-08-05

Structural insights into µ-opioid receptor activation

Jan Steyaert, Evan N Feinberg, Hideaki E. Kato, William I Weis, Stephen M. Husbands, Peter Gmeiner, Brian Kobilka, Aashish Manglik, Ron Ofer Dror
2015-03-21

Rapid and facile recombinant expression of bovine rhodopsin in HEK293S GnTI(-) cells using a PiggyBac inducible system.

Zhijie Li
2015-01-20

The guanine nucleotide exchange factor Ric-8A induces domain separation and Ras domain plasticity in Gαi1.

Wayne L. Hubbell
2014-07-31

Position of transmembrane helix 6 determines receptor G protein coupling specificity.

Alexander S Rose, Ulrich Zachariae, Patrick Scheerer, Klaus Peter Hofmann
2014-03-18

Mapping protein conformational heterogeneity under pressure with site-directed spin labeling and double electron-electron resonance

Wayne L. Hubbell
2013-08-20

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald
2013-06-25

PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data

Thomas E. Cheatham, III
2012-11-28

Automation of the CHARMM General Force Field (CGenFF) I: bond perception and atom typing

Kenno Vanommeslaeghe, Alex MacKerell
2012-11-28

Automation of the CHARMM General Force Field (CGenFF) II: assignment of bonded parameters and partial atomic charges

Kenno Vanommeslaeghe, Alex MacKerell
2012-01-23

Structure and activation of rhodopsin

Karsten Melcher
2011-09-29

Crystal structure of the β2 adrenergic receptor-Gs protein complex

Jan Steyaert, Els Pardon, Joseph A Lyons, Martin Caffrey, William I Weis, Jesper M Mathiesen, Georgios Skiniotis, Brian Kobilka, Tong Sun Kobilka, Pil Seok Chae, Søren G. F. Rasmussen, Roger K Sunahara, Foon Sun Thian, Samuel H. Gellman, Yaozhong Zou
2011-05-23

Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit

Jens Meiler, Anita Preininger, Wayne L. Hubbell
2011-03-09

Crystal structure of metarhodopsin II

Emil F. Pai, Norbert Krauß, Patrick Scheerer, Oliver Ernst, Klaus Peter Hofmann
2010-06-01

Update of the CHARMM all-atom additive force field for lipids: validation on six lipid types
2010-03-01

CHARMM general force field: A force field for drug-like molecules compatible with the CHARMM all-atom additive biological force fields

Kenno Vanommeslaeghe, Alex MacKerell
2009-11-06

Structural evidence for a sequential release mechanism for activation of heterotrimeric G proteins
2009-05

Structural origin of weakly ordered nitroxide motion in spin-labeled proteins

Duilio Cascio, Wayne L. Hubbell
2008-11-07

Two protonation switches control rhodopsin activation in membranes
2008-09-01

Crystal structure of opsin in its G-protein-interacting conformation

Patrick Scheerer, Norbert Krauß, Oliver Ernst, Klaus Peter Hofmann
2008-06-18

Crystal structure of the ligand-free G-protein-coupled receptor opsin

Patrick Scheerer, Oliver Ernst, Klaus Peter Hofmann
2008-05-19

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

Wayne L. Hubbell, Klaus Peter Hofmann
2007-10-05

Crystal Structure of a Thermally Stable Rhodopsin Mutant

Jörg Standfuss

Article - wd:Q49790548

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