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Animal models of monoclonal immunoglobulin-related renal diseases.

著者

Christophe Sirac

Michel Cogné

Vincent Javaugue

Frank Bridoux

この作品が含まれる作品: Nature Reviews Nephrology

出版日: 2018-02-19

言語: 英語

Cites articles 134

Date

タイトル

著者

2017-03-16

Regulated expression of amyloidogenic immunoglobulin light chains in mice

Silvia Sorce, Paola Rognoni, Mario Nuvolone, Giovanni Palladini, Adriano Aguzzi, Giampaolo Merlini
2017-03-24

Encouraging impact of doxycycline on early mortality in cardiac light chain (AL) amyloidosis
2017-03-03

Cardiac Light Chain Amyloidosis: The Role of Metal Ions in Oxidative Stress and Mitochondrial Damage

Paola Rognoni, Marten Beeg, Claudia Foray, Giovanni Palladini, Giampaolo Merlini
2017-01-27

The amyloidogenic light chain is a stressor that sensitizes plasma cells to proteasome inhibitor toxicity

Giovanni Palladini, Paolo Milani, Simone Cenci, Enrico Milan, Paola Rognoni, Thierry Touvier, Giampaolo Merlini, Laura Cristina Luna Oliva, Fulvia Cerruti, Ugo Orfanelli, Andrea Raimondi, Massimo Resnati, Magda Marcatti, Fabio Ciceri
2017-01-11

Differences in Protein Concentration Dependence for Nucleation and Elongation in Light Chain Amyloid Formation

Luis M Blancas-Mejia, Pinaki P Misra
2016-04-21

[Randall-type monoclonal immunoglobulin deposition disease: From diagnosis to treatment]

Arnaud Jaccard, Christophe Sirac
2016-10-20

Unravelling the immunopathological mechanisms of heavy chain deposition disease with implications for clinical management

Amélie Bonaud, Patrick Trouillas, Florent Di Meo, Michel Cogné, Christophe Sirac, Jean-Michel Goujon, Nathalie Quellard, Vincent Javaugue, Sébastien Bender, Pierre Aucouturier, Frank Bridoux
2016-02-08

First-in-Human Phase I/II Study of NEOD001 in Patients With Light Chain Amyloidosis and Persistent Organ Dysfunction

Giampaolo Merlini, Stefan Schönland, Morie A Gertz
2016-07-25

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

Mohamed-Amine Hamouda, Arnaud Jacquel, Guillaume Robert, Alexandre Puissant, Sandrine Roulland, Jerome Gilleron, Emmanuel Griessinger, Alix Dubois, Béatrice Bailly-Maitre, Diogo Goncalves, Pascal Colosetti, Sandrine Marchetti, Nathalie Rochet, Marcel Deckert, Herve Avet-Loiseau, Paul Hofman, Claudine Blin-Wakkach, Bertrand Nadel, Thomas Cluzeau, Kenneth C. Anderson, Patrick Auberger, Frédéric Luciano
2016-01-22

Animal Models of Light Chain Deposition Disease Provide a Better Understanding of Nodular Glomerulosclerosis.
2015-01-21

Diagnosis of monoclonal gammopathy of renal significance

Giampaolo Merlini, Angela Dispenzieri, Murielle Roussel, Efstathios Kastritis, Nelson Leung, ロバート・A・カイル, Frank Bridoux, Sanjeev Sethi, Jean Paul Fermand, Maria M Picken, Fernando C Fervenza
2015-11-27

Impaired Lysosomal Function Underlies Monoclonal Light Chain-Associated Renal Fanconi Syndrome

Christophe Sirac, Amélie Bonaud, Michel Cogné, Vincent Javaugue, Sébastien Bender, Pierre Aucouturier, Frank Bridoux
2015-06-25

A mouse model recapitulating human monoclonal heavy chain deposition disease evidences the relevance of proteasome inhibitor therapy

Amélie Bonaud, Sébastien Bender, Laurent Delpy, Anne Druilhe, Michel Cogné, Christophe Sirac, Nathalie Quellard, Nivine Srour, Vincent Javaugue, Frank Bridoux
2015-07-15

Bortezomib produces high hematological response rates with prolonged renal survival in monoclonal immunoglobulin deposition disease.

Arnaud Jaccard, Sylvie Chevret
2015-04-09

Circulating monoclonal light chains and acute kidney injury: the role of the renal biopsy with emphasis on ultrastructural evaluation in assessing and understanding renal injury
2015-07-15

Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component

Mark Pepys, James Moon
2015-12-14

A plasma cell differentiation quality control ablates B cell clones with biallelic Ig rearrangements and truncated Ig production

Guillaume Chemin, Mohamad Omar Ashi, Sophie Peron, Christophe Sirac, Michel Cogné, Laurent Delpy, Nivine Srour, Aurélien Tinguely
2014-10-01

Proximal tubulopathies associated with monoclonal light chains: the spectrum of clinicopathologic manifestations and molecular pathogenesis
2014-08-04

Decreased amyloidogenicity caused by mutational modulation of surface properties of the immunoglobulin light chain BRE variable domain

Daizo Hamada
2014-04-30

An animal model of glomerular light-chain-associated amyloidogenesis depicts the crucial role of lysosomes
2014-03-24

A Caenorhabditis elegans-based assay recognizes immunoglobulin light chains causing heart amyloidosis

Paola Rognoni, Francesca Lavatelli, Margherita Romeo, Elena del Favero, Giovanni Palladini, Mario Salmona, Giampaolo Merlini
2014-04-10

One siRNA pool targeting the λ constant region stops λ light-chain production and causes terminal endoplasmic reticulum stress
2014-01-24

Extrusion of amyloid fibrils to the extracellular space in experimental mesangial AL-amyloidosis: transmission and scanning electron microscopy studies and correlation with renal biopsy observations
2014-01-22

Phagocyte depletion inhibits AA amyloid accumulation in AEF-induced huIL-6 transgenic mice

Jonathan S Wall
2014-11-01

Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity

Lawreen H Connors
2014-07-16

A matched comparison of cyclophosphamide, bortezomib and dexamethasone (CVD) versus risk-adapted cyclophosphamide, thalidomide and dexamethasone (CTD) in AL amyloidosis

Helen J Lachmann
2014-07-25

Melphalan and dexamethasone with or without bortezomib in newly diagnosed AL amyloidosis: a matched case-control study on 174 patients

Giovanni Palladini, Paolo Milani, Francesca Lavatelli, Mario Nuvolone, Laura Obici, Stefano Perlini, Giampaolo Merlini
2014-05-23

Efficacy of bortezomib, cyclophosphamide and dexamethasone in treatment-naïve patients with high-risk cardiac AL amyloidosis (Mayo Clinic stage III)

Arnaud Jaccard, Parameswaran Hari, Murielle Roussel
2013-10-09

How I treat monoclonal gammopathy of renal significance (MGRS).

Angela Dispenzieri, Mark Cook, Efstathios Kastritis, Nelson Leung, ロバート・A・カイル
2013-02-28

Systemic amyloidoses
2013-01-09

The diagnosis and characteristics of renal heavy-chain and heavy/light-chain amyloidosis and their comparison with renal light-chain amyloidosis

Angela Dispenzieri, Morie A Gertz, Francis K Buadi, Sanjeev Sethi, Bonnie Lynn Valant-Spaight, Anthony M Valeri, Jason D Theis, Julie A Vrana, Samar Said
2013-09-27

A strategy for synthesis of pathogenic human immunoglobulin free light chains in E. coli

Paola Rognoni, Francesca Lavatelli, Giovanni Palladini, Paolo Pedrazzoli, Giampaolo Merlini

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