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Essential role of MD-2 in LPS responsiveness and TLR4 distribution.

author

Yoichiro Iwakura

published in: Nature Immunology

date of publication: 2002-06-10

language: English

main subject: toll-like receptor

Cites articles 36

Date

Title

Authors

2002

Innate immune recognition

Ruslan Medzhitov
2002-03-01

Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide

Yoichiro Iwakura
2002-03-01

Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells

Teresa Frisan, Agneta Richter-Dahlfors
2002-03-25

Human Toll-like receptor 4 recognizes host-specific LPS modifications

Adeline Hajjar, S I Miller
2001-11-12

MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor
2001-09-15

N-linked glycosylations at Asn(26) and Asn(114) of human MD-2 are required for toll-like receptor 4-mediated activation of NF-kappaB by lipopolysaccharide
2001-07-02

Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling
2001-10-09

Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4
2001-10-01

Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability
2001-01-01

Cutting edge: Gln22 of mouse MD-2 is essential for species-specific lipopolysaccharide mimetic action of taxol
2001-12

Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition
2000-08-17

Toll-like receptors in the induction of the innate immune response
2000-07-01

Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1.
2000-04-01

Cutting edge: cell surface expression and lipopolysaccharide signaling via the toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages.
2000-03-01

ER-Tracker dye and BODIPY-brefeldin A differentiate the endoplasmic reticulum and golgi bodies from the tubular-vacuole system in living hyphae of Pisolithus tinctorius

Louise Cole, Geoffrey J. Hyde
2000-01-28

Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol
2000-02-29

Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation

Bruce Beutler
2000-02-01

Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide
2000-04-01

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

Jun-ichi Miyazaki
2000-07-03

The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells

Klaus Rajewsky
2000-06

Plat-E: an efficient and stable system for transient packaging of retroviruses
1999-02-01

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

Danielle Malo, Philippe Gros
1999-06-07

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
1999-10-01

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
1999-08-01

Transport of bacterial lipopolysaccharide to the golgi apparatus
1999-10-01

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens

David M Underhill, Adeline Hajjar
1998-01-20

A family of human receptors structurally related to Drosophila Toll
1998-12-11

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene,Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene

Bruce Beutler
1998-07-01

The molecular mechanism of B cell activation by toll-like receptor protein RP-105

Klaus Rajewsky
1997-07-24

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
1996-04-01

The instructive role of innate immunity in the acquired immune response
1995-01-01

Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin

Article - wd:Q50109313

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