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Virus-like infection induces human β cell dedifferentiation.

auteur

M Bugliani

Pratik Choudhary

Raphael Scharfmann

gepubliceerd in: JCI insight

publicatiedatum: 2018-02-08

Cites articles 48

Date

Titel

Auteurs

2017-04-10

Analysis of Purified Pancreatic Islet Beta and Alpha Cell Transcriptomes Reveals 11β-Hydroxysteroid Dehydrogenase (Hsd11b1) as a Novel Disallowed Gene

Timothy J Pullen, Mark O Huising, Guy A. Rutter
2017-09-11

Coxsackievirus-Induced Proteomic Alterations in Primary Human Islets Provide Insights for the Etiology of Diabetes.
2017-02-04

β Cells that Resist Immunological Attack Develop during Progression of Autoimmune Diabetes in NOD Mice.

Kevan C Herold
2016-08-30

Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice

Domenico Accili
2016-07-20

SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc

C D Oh, Zhaoping Zhang, Benoit de Crombrugghe, Hideyo Yasuda
2016-07-01

Viruses in type 1 diabetes

Heikki Hyöty
2016-06-14

Increased Hormone-Negative Endocrine Cells in the Pancreas in Type 1 Diabetes
2016-05-11

Extracellular acidification stimulates GPR68 mediated IL-8 production in human pancreatic β cells

Angeliki Karamitri, Françoise Cormier, Raphael Scharfmann
2016-03-29

Viral infections in type 1 diabetes mellitus--why the β cells?
2016-02-22

Xenotropic retrovirus Bxv1 in human pancreatic β cell lines

Philippe Ravassard, Signe Z Ingvarsen, Raphael Scharfmann
2015-12-29

Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes

Domenico Accili, Lorella Marselli
2015-10-01

Mechanisms of Beta Cell Dysfunction Associated With Viral Infection
2015-08-03

TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells

Laura Marroquí, Reinaldo Sousa dos Santos, Izortze Santin, Lorella Marselli, Flemming Pociot
2014-11-24

Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes

Heikki Hyöty, Johnny Ludvigsson, Pia Leete, Oskar Skog, Sarah J. Richardson, Bjørn Edwin, Noel G Morgan, Dag Undlien, Olle Korsgren
2014-11-12

Viral infection of engrafted human islets leads to diabetes

Bruce Barton, Jennifer P Wang
2014-11-12

Connective tissue growth factor modulates adult β-cell maturity and proliferation to promote β-cell regeneration in mice

Raymond C Pasek, Jennifer Peek, Herrera PL
2014-09-26

Human fucci pancreatic Beta cell lines: new tools to study Beta cell cycle and terminal differentiation

Corinne Cordier, Raphael Scharfmann
2014-05-10

Sox9: a master regulator of the pancreatic program

Philip Seymour
2014-05-14

PTBP1 is required for glucose-stimulated cap-independent translation of insulin granule proteins and Coxsackieviruses in beta cells
2014-05-01

MicroRNA-7a regulates pancreatic β cell function

Jean Hausser, Mihaela Zavolan, Patrik Rorsman, Lena Eliasson, François Pattou, Sofia Gargani, Benoit Hastoy, Markus Stoffel, Mathieu Latreille, Jonathan Lou S Esguerra
2013-12-01

VHL-mediated disruption of Sox9 activity compromises β-cell identity and results in diabetes mellitus
2012-11-22

When less is more: the forbidden fruits of gene repression in the adult β-cell
2012-09-01

Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure

Hua Lin, Domenico Accili
2012-10-14

Expression of the enteroviral capsid protein VP1 in the islet cells of patients with type 1 diabetes is associated with induction of protein kinase R and downregulation of Mcl-1

Sarah J. Richardson, Pia Leete, Noel G Morgan
2011-10-03

Elevated Hedgehog/Gli signaling causes beta-cell dedifferentiation in mice

Limor Landsman
2011-08-29

Connective tissue growth factor acts within both endothelial cells and beta cells to promote proliferation of developing beta cells

Aris Economides
2011-08-25

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

Philippe Ravassard
2010-08-10

Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study

Alessandro Doria, George Eisenbarth
2010-03-30

Pathogenesis of type 1 diabetes mellitus: interplay between enterovirus and host

D Hober
2009-03-06

The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes

Sarah J. Richardson, Abby Willcox, Noel G Morgan
2009-01-08

Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis

Andrew J Murphy, Aris Economides
2009-02-01

Amino acids of Coxsackie B5 virus are critical for infection of the murine insulinoma cell line, MIN-6

Haider Al-Hello, Teemu Smura, Petri Ylipaasto, Tapani Hovi, Merja Roivainen

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